PH22224A - Phosphorus containing amide compounds and pharmaceutical compositions containing them - Google Patents
Phosphorus containing amide compounds and pharmaceutical compositions containing themInfo
- Publication number
- PH22224A PH22224A PH30157A PH30157A PH22224A PH 22224 A PH22224 A PH 22224A PH 30157 A PH30157 A PH 30157A PH 30157 A PH30157 A PH 30157A PH 22224 A PH22224 A PH 22224A
- Authority
- PH
- Philippines
- Prior art keywords
- pharmaceutical compositions
- amide compounds
- phosphorus
- compositions containing
- phosphorus containing
- Prior art date
Links
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 title 1
- -1 amide compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229910052698 phosphorus Inorganic materials 0.000 title 1
- 239000011574 phosphorus Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/32—Esters thereof
- C07F9/3205—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/3211—Esters of acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3882—Arylalkanephosphonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46189583A | 1983-01-28 | 1983-01-28 | |
| US54432283A | 1983-10-21 | 1983-10-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH22224A true PH22224A (en) | 1988-07-01 |
Family
ID=27040169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH30157A PH22224A (en) | 1983-01-28 | 1984-01-24 | Phosphorus containing amide compounds and pharmaceutical compositions containing them |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0117429B1 (da) |
| AU (1) | AU569719B2 (da) |
| CA (1) | CA1223266A (da) |
| DE (1) | DE3465740D1 (da) |
| DK (1) | DK31784A (da) |
| GR (1) | GR81744B (da) |
| HU (1) | HU191987B (da) |
| IE (1) | IE56605B1 (da) |
| IL (1) | IL70780A (da) |
| NZ (1) | NZ206920A (da) |
| PH (1) | PH22224A (da) |
| PT (1) | PT78003B (da) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5217963A (en) * | 1985-05-24 | 1993-06-08 | Ciba-Geigy Corporation | Certain phosphonic acid quinoline-2-carboxylic acids, esters or amides useful for treatment of disorders responsive to N-methyl D-aspartate receptor blockade |
| US4906621A (en) * | 1985-05-24 | 1990-03-06 | Ciba-Geigy Corporation | Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade |
| US4746653A (en) * | 1986-02-28 | 1988-05-24 | Ciba-Geigy Corporation | Certain hetero phosphonic acid derivatives of 2-piperidine or 2-tetrahydropyridinecarboxylates and esters thereof which are useful for the treatment of disorders responsive to blockade of the NMDA receptor in mammals |
| EP0254032A3 (en) | 1986-06-20 | 1990-09-05 | Schering Corporation | Neutral metalloendopeptidase inhibitors in the treatment of hypertension |
| US4749688A (en) * | 1986-06-20 | 1988-06-07 | Schering Corporation | Use of neutral metalloendopeptidase inhibitors in the treatment of hypertension |
| CA1337400C (en) * | 1987-06-08 | 1995-10-24 | Norma G. Delaney | Inhibitors of neutral endopeptidase |
| US4963539A (en) * | 1987-09-10 | 1990-10-16 | E. R. Squibb & Sons, Inc. | Phosphonate and phosphonamide endopeptidase inhibitors |
| WO1990001940A1 (en) * | 1988-08-18 | 1990-03-08 | California Biotechnology Inc. | Atrial natriuretic peptide clearance inhibitors |
| DK244090D0 (da) * | 1990-10-09 | 1990-10-09 | Novo Nordisk As | Kemiske forbindelser |
| US5294632A (en) * | 1991-05-01 | 1994-03-15 | Ciba-Geigy Corporation | Phosphono/biaryl substituted dipetide derivatives |
| US5155100A (en) * | 1991-05-01 | 1992-10-13 | Ciba-Geigy Corporation | Phosphono/biaryl substituted dipeptide derivatives |
| US5250522A (en) * | 1992-10-09 | 1993-10-05 | Ciba-Geigy Corporation | Phosphono/biaryl substituted amino acid derivatives |
| US5473092A (en) * | 1992-11-20 | 1995-12-05 | Monsanto Company | Synthesis of optically-active phosphono analogs of succinates |
| IT1266570B1 (it) * | 1993-07-30 | 1997-01-09 | Zambon Spa | Derivati della propanammide n-eteroaril sostituiti utili nel trattamento delle malattie cardiovascolari |
| ATE253073T1 (de) * | 1997-03-07 | 2003-11-15 | Metabasis Therapeutics Inc | Neue benzimidazol inhibitoren der fructose-1,6- bisphosphatase |
| US6284748B1 (en) | 1997-03-07 | 2001-09-04 | Metabasis Therapeutics, Inc. | Purine inhibitors of fructose 1,6-bisphosphatase |
| DE102005022843A1 (de) * | 2005-05-18 | 2006-11-23 | Construction Research & Technology Gmbh | Phosphor-haltige Monomere, Verfahren zu ihrer Herstellung sowie deren Verwendung |
| MA33364B1 (fr) | 2009-05-28 | 2012-06-01 | Novartis Ag | Dérivés aminobutyriques substitués en tant qu'inhibiteurs de néprilysine |
| EA019511B1 (ru) | 2009-05-28 | 2014-04-30 | Новартис Аг | Замещенные производные аминопропионовой кислоты в качестве ингибиторов неприлизина |
| JO2967B1 (en) | 2009-11-20 | 2016-03-15 | نوفارتس ايه جي | Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors |
| SI2956464T1 (en) | 2013-02-14 | 2018-08-31 | Novartis Ag | Substituted bisphenyl butanoic phosphonic acid derivatives as NEP inhibitors (neutral endopeptidases) |
| JP6301371B2 (ja) | 2013-02-14 | 2018-04-11 | ノバルティス アーゲー | インビボ効力が改善されたｎｅｐ阻害剤としての置換ビスフェニルブタン酸誘導体 |
| GB201704476D0 (en) | 2017-03-21 | 2017-05-03 | Antabio Sas | Chemical compounds |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH584232A5 (da) * | 1973-07-26 | 1977-01-31 | Ciba Geigy Ag | |
| US4191552A (en) * | 1979-02-02 | 1980-03-04 | Stauffer Chemical Company | Amine salts of substituted N-phosphonomethylureas and their use as plant growth regulators |
| US4272528A (en) * | 1980-08-14 | 1981-06-09 | Abbott Laboratories | Phosphonoacetyl aminoacids |
| IE53128B1 (en) * | 1981-06-19 | 1988-07-06 | Monsanto Co | Herbicidally active monoesters and diesters of n-alkyl substituted amino methyl phosphonic acid and process for preparing the diesters |
| AU8571982A (en) * | 1981-07-09 | 1983-01-13 | Analytical Research Pharmaceuticals Pty. Ltd. | Phosphonoalkanoyl-amino acids |
| EP0070131A1 (en) * | 1981-07-09 | 1983-01-19 | Analytical Research Pharmaceuticals Pty. Ltd. | Phosphonoalkanoylamino acids |
| US4396772A (en) * | 1981-11-23 | 1983-08-02 | F. R. Squibb & Sons, Inc. | Phosphinylalkanoyl amino acids |
-
1984
- 1984-01-24 AU AU23736/84A patent/AU569719B2/en not_active Ceased
- 1984-01-24 GR GR73604A patent/GR81744B/el unknown
- 1984-01-24 NZ NZ206920A patent/NZ206920A/en unknown
- 1984-01-24 DK DK31784A patent/DK31784A/da not_active Application Discontinuation
- 1984-01-24 PH PH30157A patent/PH22224A/en unknown
- 1984-01-24 IE IE155/84A patent/IE56605B1/xx unknown
- 1984-01-25 CA CA000445993A patent/CA1223266A/en not_active Expired
- 1984-01-25 DE DE8484100746T patent/DE3465740D1/de not_active Expired
- 1984-01-25 IL IL70780A patent/IL70780A/xx unknown
- 1984-01-25 EP EP84100746A patent/EP0117429B1/en not_active Expired
- 1984-01-25 PT PT78003A patent/PT78003B/pt not_active IP Right Cessation
- 1984-01-26 HU HU84328A patent/HU191987B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT78003A (en) | 1984-02-01 |
| DK31784D0 (da) | 1984-01-24 |
| PT78003B (en) | 1986-06-18 |
| HUT34511A (en) | 1985-03-28 |
| IL70780A (en) | 1988-02-29 |
| EP0117429A1 (en) | 1984-09-05 |
| DK31784A (da) | 1984-07-29 |
| DE3465740D1 (en) | 1987-10-08 |
| IL70780A0 (en) | 1984-04-30 |
| GR81744B (da) | 1984-12-12 |
| IE840155L (en) | 1984-07-28 |
| NZ206920A (en) | 1986-10-08 |
| AU569719B2 (en) | 1988-02-18 |
| AU2373684A (en) | 1984-08-02 |
| EP0117429B1 (en) | 1987-09-02 |
| CA1223266A (en) | 1987-06-23 |
| HU191987B (en) | 1987-04-28 |
| IE56605B1 (en) | 1991-10-09 |
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