PH12016501529B1 - Internal liquid agent - Google Patents
Internal liquid agentInfo
- Publication number
- PH12016501529B1 PH12016501529B1 PH12016501529A PH12016501529A PH12016501529B1 PH 12016501529 B1 PH12016501529 B1 PH 12016501529B1 PH 12016501529 A PH12016501529 A PH 12016501529A PH 12016501529 A PH12016501529 A PH 12016501529A PH 12016501529 B1 PH12016501529 B1 PH 12016501529B1
- Authority
- PH
- Philippines
- Prior art keywords
- liquid agent
- internal liquid
- inhibited
- pigment
- caused
- Prior art date
Links
- 239000007788 liquid Substances 0.000 title abstract 3
- QNVKOSLOVOTXKF-UHFFFAOYSA-N 4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;hydron;chloride Chemical compound Cl.NC1=C(Br)C=C(Br)C=C1CNC1CCC(O)CC1 QNVKOSLOVOTXKF-UHFFFAOYSA-N 0.000 abstract 2
- 229960000985 ambroxol hydrochloride Drugs 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 abstract 2
- 239000000049 pigment Substances 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 229960005174 ambroxol Drugs 0.000 abstract 1
- JBDGDEWWOUBZPM-XYPYZODXSA-N ambroxol Chemical compound NC1=C(Br)C=C(Br)C=C1CN[C@@H]1CC[C@@H](O)CC1 JBDGDEWWOUBZPM-XYPYZODXSA-N 0.000 abstract 1
- 235000019658 bitter taste Nutrition 0.000 abstract 1
- 238000002845 discoloration Methods 0.000 abstract 1
- 229940074391 gallic acid Drugs 0.000 abstract 1
- 235000004515 gallic acid Nutrition 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
An internal liquid agent containing ambroxol hydrochloride, a pigment, polyethylene glycol, and optional gallic acid or a derivative thereof,is an internal liquid agent, in which changes in color of the ambroxol hydhrochloride caused by irradiation of light are inhibited, no precipitate is formed, discoloration of the pigment caused by heat is inhibited, and bitter taste of ambroxol hydrochloride is suppressed.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014028361 | 2014-02-18 | ||
PCT/JP2015/054207 WO2015125757A1 (en) | 2014-02-18 | 2015-02-17 | Internal liquid agent |
Publications (2)
Publication Number | Publication Date |
---|---|
PH12016501529B1 true PH12016501529B1 (en) | 2017-02-06 |
PH12016501529A1 PH12016501529A1 (en) | 2017-02-06 |
Family
ID=53878259
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH12016501529A PH12016501529A1 (en) | 2014-02-18 | 2016-08-03 | Internal liquid agent |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP6372559B2 (en) |
PH (1) | PH12016501529A1 (en) |
WO (1) | WO2015125757A1 (en) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3949184B2 (en) * | 1995-06-13 | 2007-07-25 | テイコクメディックス株式会社 | Ambroxol hydrochloride aqueous solution |
JP2000007561A (en) * | 1998-06-18 | 2000-01-11 | Nissho Corp | Ambroxol hydrochloride aqueous solution preparation |
US20050075403A1 (en) * | 2003-10-02 | 2005-04-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol for the treatment of inflammation in the pharynx |
ITMI20032463A1 (en) * | 2003-12-16 | 2005-06-17 | Advance Holdings Ltd | AQUEOUS CONCENTRATED AMBROXOL SOLUTION |
DE102004021992A1 (en) * | 2004-05-03 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Topical preparation containing ambroxol |
-
2015
- 2015-02-17 WO PCT/JP2015/054207 patent/WO2015125757A1/en active Application Filing
- 2015-02-17 JP JP2016504098A patent/JP6372559B2/en active Active
-
2016
- 2016-08-03 PH PH12016501529A patent/PH12016501529A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
JPWO2015125757A1 (en) | 2017-03-30 |
PH12016501529A1 (en) | 2017-02-06 |
WO2015125757A1 (en) | 2015-08-27 |
JP6372559B2 (en) | 2018-08-15 |
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