PE20240149A1 - Compuestos de lactivicina, su preparacion y uso como agentes antibacterianos - Google Patents
Compuestos de lactivicina, su preparacion y uso como agentes antibacterianosInfo
- Publication number
- PE20240149A1 PE20240149A1 PE2023002758A PE2023002758A PE20240149A1 PE 20240149 A1 PE20240149 A1 PE 20240149A1 PE 2023002758 A PE2023002758 A PE 2023002758A PE 2023002758 A PE2023002758 A PE 2023002758A PE 20240149 A1 PE20240149 A1 PE 20240149A1
- Authority
- PE
- Peru
- Prior art keywords
- compounds
- lactivicin
- preparation
- antibacterial agents
- beta
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title abstract 3
- ZUEKKUYIXILDAF-WKEGUHRASA-N (2s)-2-[(4s)-4-acetamido-3-oxo-1,2-oxazolidin-2-yl]-5-oxooxolane-2-carboxylic acid Chemical class O=C1[C@@H](NC(=O)C)CON1[C@]1(C(O)=O)OC(=O)CC1 ZUEKKUYIXILDAF-WKEGUHRASA-N 0.000 title abstract 2
- 229940088710 antibiotic agent Drugs 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 239000003782 beta lactam antibiotic agent Substances 0.000 abstract 1
- 239000003781 beta lactamase inhibitor Substances 0.000 abstract 1
- 229940126813 beta-lactamase inhibitor Drugs 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002132 β-lactam antibiotic Substances 0.000 abstract 1
- 229940124586 β-lactam antibiotics Drugs 0.000 abstract 1
- 150000003952 β-lactams Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Se proporcionan compuestos de lactivicina de formula (I) y sales farmaceuticamente aceptables de los compuestos de formula (I), en donde los compuestos comprenden antibioticos adecuados para su uso solos o en combinacion con inhibidores de beta-lactamasa y/u otros antibioticos (incluidos antibioticos beta-lactamicos y no beta-lactamicos) en el tratamiento o prevencion de infecciones bacterianas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163168406P | 2021-03-31 | 2021-03-31 | |
| PCT/IB2022/052900 WO2022208356A1 (en) | 2021-03-31 | 2022-03-29 | Lactivicin compounds, their preparation and use as antibacterial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20240149A1 true PE20240149A1 (es) | 2024-02-06 |
Family
ID=83458148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2023002758A PE20240149A1 (es) | 2021-03-31 | 2022-03-29 | Compuestos de lactivicina, su preparacion y uso como agentes antibacterianos |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US11780832B2 (es) |
| EP (1) | EP4313980A1 (es) |
| JP (1) | JP2024509643A (es) |
| KR (1) | KR20230163532A (es) |
| CN (1) | CN117500802A (es) |
| AU (1) | AU2022250095B2 (es) |
| BR (1) | BR112023020056A2 (es) |
| CA (1) | CA3213971A1 (es) |
| CL (1) | CL2023002933A1 (es) |
| CO (1) | CO2023013362A2 (es) |
| CR (1) | CR20230510A (es) |
| EC (1) | ECSP23080267A (es) |
| IL (1) | IL307344A (es) |
| MA (1) | MA62917A1 (es) |
| MX (1) | MX2023011616A (es) |
| PE (1) | PE20240149A1 (es) |
| WO (1) | WO2022208356A1 (es) |
-
2022
- 2022-03-29 EP EP22779276.9A patent/EP4313980A1/en active Pending
- 2022-03-29 KR KR1020237037362A patent/KR20230163532A/ko active Search and Examination
- 2022-03-29 IL IL307344A patent/IL307344A/en unknown
- 2022-03-29 CA CA3213971A patent/CA3213971A1/en active Pending
- 2022-03-29 JP JP2023560998A patent/JP2024509643A/ja active Pending
- 2022-03-29 MA MA62917A patent/MA62917A1/fr unknown
- 2022-03-29 CN CN202280039243.9A patent/CN117500802A/zh active Pending
- 2022-03-29 BR BR112023020056A patent/BR112023020056A2/pt unknown
- 2022-03-29 AU AU2022250095A patent/AU2022250095B2/en active Active
- 2022-03-29 US US17/707,297 patent/US11780832B2/en active Active
- 2022-03-29 WO PCT/IB2022/052900 patent/WO2022208356A1/en active Application Filing
- 2022-03-29 CR CR20230510A patent/CR20230510A/es unknown
- 2022-03-29 PE PE2023002758A patent/PE20240149A1/es unknown
- 2022-03-29 MX MX2023011616A patent/MX2023011616A/es unknown
-
2023
- 2023-09-29 CL CL2023002933A patent/CL2023002933A1/es unknown
- 2023-10-06 CO CONC2023/0013362A patent/CO2023013362A2/es unknown
- 2023-10-20 EC ECSENADI202380267A patent/ECSP23080267A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO2023013362A2 (es) | 2024-01-25 |
| AU2022250095A1 (en) | 2023-11-02 |
| CR20230510A (es) | 2024-03-21 |
| JP2024509643A (ja) | 2024-03-04 |
| US20220324858A1 (en) | 2022-10-13 |
| IL307344A (en) | 2023-11-01 |
| CL2023002933A1 (es) | 2024-04-12 |
| CA3213971A1 (en) | 2022-10-06 |
| BR112023020056A2 (pt) | 2024-01-23 |
| WO2022208356A1 (en) | 2022-10-06 |
| KR20230163532A (ko) | 2023-11-30 |
| MX2023011616A (es) | 2023-10-30 |
| CN117500802A (zh) | 2024-02-02 |
| NZ804243A (en) | 2024-01-26 |
| MA62917A1 (fr) | 2024-02-29 |
| EP4313980A1 (en) | 2024-02-07 |
| AU2022250095B2 (en) | 2023-11-23 |
| ECSP23080267A (es) | 2024-01-31 |
| US11780832B2 (en) | 2023-10-10 |
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