PE20140200A1 - Metodo para producir y usar un copolimero de carboximetilcelulosa sodica y gosipol - Google Patents
Metodo para producir y usar un copolimero de carboximetilcelulosa sodica y gosipolInfo
- Publication number
- PE20140200A1 PE20140200A1 PE2013000829A PE2013000829A PE20140200A1 PE 20140200 A1 PE20140200 A1 PE 20140200A1 PE 2013000829 A PE2013000829 A PE 2013000829A PE 2013000829 A PE2013000829 A PE 2013000829A PE 20140200 A1 PE20140200 A1 PE 20140200A1
- Authority
- PE
- Peru
- Prior art keywords
- sodium
- gosipol
- weight
- carboximethyl
- carboximethylcellulose
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/02—Alkyl or cycloalkyl ethers
- C08B11/04—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
- C08B11/10—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals substituted with acid radicals
- C08B11/12—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals substituted with acid radicals substituted with carboxylic radicals, e.g. carboxymethylcellulose [CMC]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
- C08B15/02—Oxycellulose; Hydrocellulose; Cellulosehydrate, e.g. microcrystalline cellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
METODO DE PRODUCCION DE UN COPOLIMERO DE CARBOXIMETILCELULOSA SODICA CON UN GRADO DE SUSTITUCION DE 0,35 A 0,80 Y GOSIPOL, DE FORMULA 1, DONDE: a ES 1; b ES 3 A 6; c ES 5 A 7; n ES 40 A 50; CON UN PESO MOLECULAR DE 120.000-130.000. DICHO METODO COMPRENDE HACER REACCIONAR UNA DISOLUCION ACUOSA DE CARBOXIMETILCELULOSA SODICA CON UNA DISOLUCION ACUOSA DE ACIDO PERYODICO O PERYODATO DE SODIO MIENTRAS SE HACE PASAR DIOXIDO DE CARBONO HASTA ALCANZAR UN pH de 3,0 A 4,5, AISLAR DIALDEHIDO-CARBOXIMETILCELULOSA, TRATAR EL PRODUCTO RESULTANTE CON GOSIPOL O ACIDO ACETICO-GOSIPOL Y LUEGO CON UNA DISOLUCION ALCALINA ACUOSA, AISLAR EL PRODUCTO MEDIANTE PRECIPITACION CON UN DISOLVENTE ORGANICO. TAMBIEN ESTA REFERIDA A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: a) 10% A 16% EN PESO DE PRINCIPIO ACTIVO DE FORMULA 1, b) 10% A 20 % EN PESO DE ALIMIDON, c) 0.6% A 0.8% EN PESO DE ESTEARATO DE CALCIO O MAGNESIO
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2010141697/05A RU2453559C1 (ru) | 2010-10-11 | 2010-10-11 | Способ получения сополимера натрийкарбоксиметилцеллюлозы и госсипола и его применение в комплексной терапии пациентов с аутистическими расстройствами и когнитивными нарушениями |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20140200A1 true PE20140200A1 (es) | 2014-02-21 |
Family
ID=45938511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2013000829A PE20140200A1 (es) | 2010-10-11 | 2011-10-06 | Metodo para producir y usar un copolimero de carboximetilcelulosa sodica y gosipol |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US9078916B2 (es) |
| EP (1) | EP2628754B8 (es) |
| JP (1) | JP5690944B2 (es) |
| CN (1) | CN103189393B (es) |
| AU (1) | AU2011314406B2 (es) |
| BR (1) | BR112013008888B1 (es) |
| CA (2) | CA2896450A1 (es) |
| CL (2) | CL2013000962A1 (es) |
| CO (1) | CO6731081A2 (es) |
| CY (1) | CY1119413T1 (es) |
| DK (1) | DK2628754T3 (es) |
| EA (2) | EA024810B1 (es) |
| EC (1) | ECSP13012613A (es) |
| ES (1) | ES2643167T3 (es) |
| GE (1) | GEP201706607B (es) |
| HR (1) | HRP20171330T1 (es) |
| HU (1) | HUE034920T2 (es) |
| LT (1) | LT2628754T (es) |
| PE (1) | PE20140200A1 (es) |
| PL (1) | PL2628754T3 (es) |
| PT (1) | PT2628754T (es) |
| RS (1) | RS56257B1 (es) |
| RU (1) | RU2453559C1 (es) |
| SI (1) | SI2628754T1 (es) |
| UA (2) | UA108126C2 (es) |
| WO (1) | WO2012050483A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2499002C1 (ru) * | 2012-06-14 | 2013-11-20 | Общество С Ограниченной Ответственностью "Ниармедик Плюс" | Конъюгаты госсипола и натрийкарбоксиметилцеллюлозы, способы их получения и противовирусные средства на их основе |
| RU2577539C2 (ru) * | 2014-06-17 | 2016-03-20 | Общество С Ограниченной Ответственностью "Ниармедик Плюс" | Полимерные производные госсипола, способ их получения и фармацевтическая композиция на их основе |
| RU2754067C2 (ru) * | 2018-05-18 | 2021-08-25 | Общество с ограниченной ответственностью "НИАРМЕДИК ФАРМА" | Противомикробная композиция на основе полифенолов и полисахаридов, способ ее получения и применение |
| RU2746504C1 (ru) * | 2020-02-27 | 2021-04-14 | Ниармедик Интернэшнл Лимитед | Противомикробные средства на основе бета-глюканов, способы их получения и применения |
| JP7207364B2 (ja) | 2020-05-19 | 2023-01-18 | Ｊｆｅスチール株式会社 | ロッドミルのロッド交換装置及び方法 |
| CN114622407B (zh) * | 2022-04-01 | 2023-09-19 | 浙江隆腾医用新材料有限公司 | 一种羧甲基纤维素钠纤维的洗脱方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2002755C1 (ru) * | 1991-02-04 | 1993-11-15 | Научно-исследовательский институт эпидемиологии и микробиологии им.Н.Ф.Гамалеи РАМН | Производное целлюлозы и госсипола, обладающее интерферониндуцирующим и противовирусным действием |
| RU2222548C2 (ru) * | 2000-07-21 | 2004-01-27 | Зао "Ниармедик Плюс" | Применение производного целлюлозы и госсипола в качестве радиопротекторного, противоинфекционного и потенциирующего средства, усовершенствованный способ его получения и фармацевтическая композиция на его основе |
| JP4445853B2 (ja) * | 2002-06-10 | 2010-04-07 | ワイス エルエルシー | 新規ｏ−デスメチルベンラファクシンギ酸塩 |
| DE10226494A1 (de) * | 2002-06-14 | 2004-01-08 | Lts Lohmann Therapie-Systeme Ag | Filmförmige mucoadhäsive Darreichungsformen zur Verabreichung von Cannabis-Wirkstoffen |
| RU2238122C1 (ru) * | 2003-01-20 | 2004-10-20 | Ооо "Ниармедик Плюс" | Противоинфекционный фармацевтический препарат |
| RU2270708C1 (ru) * | 2004-05-26 | 2006-02-27 | Ооо "Ниармедик Плюс" | Натриевая соль сополимера карбоксиметилцеллюлозы и госсипола, фармацевтическая композиция и способ профилактики или лечения вирусных заболеваний |
| US20060144723A1 (en) * | 2004-11-02 | 2006-07-06 | Mary Fuller | Device for securing valuables |
| US20070003621A1 (en) * | 2005-06-23 | 2007-01-04 | Spherics, Inc. | Dosage forms for movement disorder treatment |
| US20090285865A1 (en) * | 2008-05-14 | 2009-11-19 | Shalaby Shalaby W | Palatable, solid oral formulations for male chemical sterilization |
-
2010
- 2010-10-11 RU RU2010141697/05A patent/RU2453559C1/ru active
-
2011
- 2011-06-10 UA UAA201305876A patent/UA108126C2/ru unknown
- 2011-10-06 AU AU2011314406A patent/AU2011314406B2/en not_active Ceased
- 2011-10-06 EA EA201390530A patent/EA024810B1/ru active IP Right Revival
- 2011-10-06 CA CA2896450A patent/CA2896450A1/en not_active Abandoned
- 2011-10-06 ES ES11832823.6T patent/ES2643167T3/es active Active
- 2011-10-06 GE GEAP201113083A patent/GEP201706607B/en unknown
- 2011-10-06 RS RS20170877A patent/RS56257B1/sr unknown
- 2011-10-06 SI SI201131286T patent/SI2628754T1/en unknown
- 2011-10-06 PL PL11832823T patent/PL2628754T3/pl unknown
- 2011-10-06 WO PCT/RU2011/000785 patent/WO2012050483A1/ru active Application Filing
- 2011-10-06 JP JP2013533814A patent/JP5690944B2/ja not_active Expired - Fee Related
- 2011-10-06 US US13/877,416 patent/US9078916B2/en not_active Expired - Fee Related
- 2011-10-06 LT LTEP11832823.6T patent/LT2628754T/lt unknown
- 2011-10-06 BR BR112013008888-5A patent/BR112013008888B1/pt not_active IP Right Cessation
- 2011-10-06 HU HUE11832823A patent/HUE034920T2/en unknown
- 2011-10-06 UA UAA201411350A patent/UA108975C2/ru unknown
- 2011-10-06 EA EA201690544A patent/EA031316B1/ru active IP Right Revival
- 2011-10-06 PT PT118328236T patent/PT2628754T/pt unknown
- 2011-10-06 DK DK11832823.6T patent/DK2628754T3/da active
- 2011-10-06 PE PE2013000829A patent/PE20140200A1/es active IP Right Grant
- 2011-10-06 CA CA2811583A patent/CA2811583C/en not_active Expired - Fee Related
- 2011-10-06 EP EP11832823.6A patent/EP2628754B8/en active Active
- 2011-10-06 CN CN201180048898.4A patent/CN103189393B/zh not_active Expired - Fee Related
-
2013
- 2013-04-10 CL CL2013000962A patent/CL2013000962A1/es unknown
- 2013-05-09 EC ECSP13012613 patent/ECSP13012613A/es unknown
- 2013-05-10 CO CO13117014A patent/CO6731081A2/es unknown
-
2015
- 2015-05-05 CL CL2015001180A patent/CL2015001180A1/es unknown
-
2017
- 2017-09-05 HR HRP20171330TT patent/HRP20171330T1/hr unknown
- 2017-09-14 CY CY20171100974T patent/CY1119413T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20140200A1 (es) | Metodo para producir y usar un copolimero de carboximetilcelulosa sodica y gosipol | |
| MY156938A (en) | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | |
| AU2018236805B2 (en) | Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives | |
| MX2020005956A (es) | Sales organicas de acido sulfonico de esteres de aminoacidos y proceso para su preparacion. | |
| EA201591639A1 (ru) | Обработка гидроксикарбоновых кислот с получением полимеров | |
| MY158663A (en) | Fermentation broth formulations | |
| MY183859A (en) | Gastroretentive drug formulation and delivery systems and their method of preparation using functionalized calcium carbonate | |
| NZ603762A (en) | Production of soluble protein solutions from pulses | |
| UA105229C2 (uk) | Фармацевтичний склад | |
| MX2013003034A (es) | Lactamas piperidinilo-substituidas como moduladores de gpr119. | |
| AU2013328639A8 (en) | Fast disintegrating solid dosage form formulation comprising functionalized calcium carbonate and method of their manufacture | |
| BR112012028766A2 (pt) | processo para a preparação de complexos de insulina e zinco | |
| BR112013000282A2 (pt) | derivados do ácido (2-arilóxi-acetilamino)-fenil-propiônico, método para produzir o mesmo e a utilização dos mesmos como produtos farmacêuticos | |
| MX2010008051A (es) | Nuevos derivados de fluoroglicosidos aromaticos, productos farmaceuticos que comprenden dichos compuestos y uso de los mismos. | |
| CY1115590T1 (el) | Σουλφοξιμινυποκατεστημενα παραγωγα ανιλινοπυριμιδινης ως cdk-αναστολεις, η παραγωγη αυτων και η χρηση αυτων ως φαρμακευτικα μεσα | |
| AR063747A1 (es) | Definilazetidinona sustituida con acido piperazina-1-sulfonico y que tiene propiedades farmacologicas mejoradas | |
| NZ602450A (en) | Agomelatine hydrochloride hydrate and preparation thereof | |
| NZ593787A (en) | Lyophilised dabigatran | |
| AR088963A1 (es) | Complejo obtenido a partir de mezclas de acido hialuronico o una sal del mismo y sulfato de condroitina | |
| BR112013018298A2 (pt) | compostos para a redução da produção de beta-amiloides | |
| AR082965A1 (es) | Metodo de preparacion de amidas de acido hialuronico altamente sustituidas | |
| GEP20156312B (en) | Improved process for preparing soluble granules of salts of pyridine – carboxylic acids | |
| MX2013003581A (es) | Proceso para producir granulos que comprende una o mas sales de agentes complejas. | |
| PE20121481A1 (es) | Formulacion de liberacion sostenida | |
| EA200900836A1 (ru) | Способ получения высокочистой внутренней соли 3-карбокси-n,n,n-триметил-1-пропанаминий гидроксида |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |