PE20120527A1 - PEPTIDOMIMETICS DERIVED FROM METHIONINE AND ITS USE IN THE PROTECTION OF MITOCHONDRIAS IN SKIN CELLS - Google Patents
PEPTIDOMIMETICS DERIVED FROM METHIONINE AND ITS USE IN THE PROTECTION OF MITOCHONDRIAS IN SKIN CELLSInfo
- Publication number
- PE20120527A1 PE20120527A1 PE2011001659A PE2011001659A PE20120527A1 PE 20120527 A1 PE20120527 A1 PE 20120527A1 PE 2011001659 A PE2011001659 A PE 2011001659A PE 2011001659 A PE2011001659 A PE 2011001659A PE 20120527 A1 PE20120527 A1 PE 20120527A1
- Authority
- PE
- Peru
- Prior art keywords
- methionine
- agents
- mitochondrias
- protection
- skin cells
- Prior art date
Links
Landscapes
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A UN PEPTIDOMIMETICO DERIVADO DE LA METIONINA DE FORMULA (II) DONDE R ES X-C(O)-NH-, EN DONDE X ES ALQUIL O ALQUILOXI(C1-C8); R' ES H. SIENDO UN COMPUESTO PREFERIDO EL N-ACETIL-(DL)-METIONIL-4-(METILTIO)PROPILAMINA. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA PARA ADMINISTRACION POR VIA TOPICA CUTANEA QUE CONTIENE i) EL PEPTIDOMIMETICO DERIVADO DE LA METIONINA EN UNA CANTIDAD DE 0.1% A 10% EN PESO DE LA COMPOSICION; E ii) ACTIVOS ADICIONALES TALES COMO AGENTES QUE ESTIMULAN LA PRODUCCION DE FACTORES DE CRECIMIENTO, AGENTES QUE AUMENTAN LA SINTESIS DE ELASTINA O PREVIENEN SU DANO, AGENTES QUE AUMENTAN LA PROLIFERACION O LA DIFERENCIACION DE LOS QUERATINOCITOS, ENTRE OTROS. DICHO COMPUESTO ES UTIL EN CONTRA DE LOS DESORDENES CUTANEOS ASOCIADOS A UNA DISFUNCION MITOCONDRIALREFERS TO A PEPTIDOMIMETIC DERIVED FROM THE METHIONINE OF FORMULA (II) WHERE R IS X-C (O) -NH-, WHERE X IS ALKYL OR ALKYLOXY (C1-C8); R 'IS H. N-ACETYL- (DL) -MEthionyl-4- (METHYLTHI) PROPYLAMINE BEING A PREFERRED COMPOUND. IT ALSO REFERS TO A PHARMACEUTICAL COMPOSITION FOR ADMINISTRATION BY TOPICAL CUTANEOUS ROUTE THAT CONTAINS i) THE PEPTIDOMIMETIC DERIVED FROM METHIONINE IN AN AMOUNT OF 0.1% TO 10% BY WEIGHT OF THE COMPOSITION; AND ii) ADDITIONAL ASSETS SUCH AS AGENTS THAT STIMULATE THE PRODUCTION OF GROWTH FACTORS, AGENTS THAT INCREASE THE SYNTHESIS OF ELASTIN OR PREVENT ITS DAMAGE, AGENTS THAT INCREASE THE PROLIFERATION OR DIFFERENTIATION OF KERATINOCITS, AMONG OTHERS. SAID COMPOUND IS USEFUL AGAINST SKIN DISORDERS ASSOCIATED WITH MITOCHONDRIAL DYSFUNCTION
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MC2573A MC200132A1 (en) | 2010-09-17 | 2010-09-17 | Peptidomimetics derived from methionine and their use in the protection of cutaneous cell mitochondria. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20120527A1 true PE20120527A1 (en) | 2012-05-17 |
Family
ID=43859585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2011001659A PE20120527A1 (en) | 2010-09-17 | 2011-09-16 | PEPTIDOMIMETICS DERIVED FROM METHIONINE AND ITS USE IN THE PROTECTION OF MITOCHONDRIAS IN SKIN CELLS |
Country Status (7)
| Country | Link |
|---|---|
| CN (1) | CN102442931B (en) |
| AR (1) | AR083004A1 (en) |
| BR (1) | BRPI1104914B1 (en) |
| CO (1) | CO6640060A1 (en) |
| MC (1) | MC200132A1 (en) |
| MX (1) | MX2011009741A (en) |
| PE (1) | PE20120527A1 (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2623396B1 (en) * | 1987-11-25 | 1990-03-30 | Sanofi Sa | USE OF ADEMETIONINE AGAINST AGING SKIN |
| CN101232877A (en) * | 2005-04-21 | 2008-07-30 | 格伦·A·戈尔茨坦 | N-acetylcysteine amide (NAC amide) for the treatment of diseases and conditions associated with oxidative stress |
-
2010
- 2010-09-17 MC MC2573A patent/MC200132A1/en unknown
-
2011
- 2011-09-15 MX MX2011009741A patent/MX2011009741A/en active IP Right Grant
- 2011-09-15 CN CN201110274029.5A patent/CN102442931B/en not_active Expired - Fee Related
- 2011-09-16 CO CO11120638A patent/CO6640060A1/en unknown
- 2011-09-16 PE PE2011001659A patent/PE20120527A1/en not_active Application Discontinuation
- 2011-09-16 AR ARP110103374 patent/AR083004A1/en active IP Right Grant
- 2011-09-16 BR BRPI1104914-6A patent/BRPI1104914B1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| MX2011009741A (en) | 2012-06-22 |
| MC200132A1 (en) | 2011-03-30 |
| CN102442931B (en) | 2015-06-03 |
| BRPI1104914A2 (en) | 2013-03-19 |
| CN102442931A (en) | 2012-05-09 |
| AR083004A1 (en) | 2013-01-23 |
| BRPI1104914B1 (en) | 2019-06-18 |
| CO6640060A1 (en) | 2013-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |