PE20030602A1 - PHARMACEUTICAL COMPOSITION INCLUDING A MACROLIDE - Google Patents

PHARMACEUTICAL COMPOSITION INCLUDING A MACROLIDE

Info

Publication number
PE20030602A1
PE20030602A1 PE2002000948A PE2002000948A PE20030602A1 PE 20030602 A1 PE20030602 A1 PE 20030602A1 PE 2002000948 A PE2002000948 A PE 2002000948A PE 2002000948 A PE2002000948 A PE 2002000948A PE 20030602 A1 PE20030602 A1 PE 20030602A1
Authority
PE
Peru
Prior art keywords
pharmaceutical composition
macrolide
composition including
rapamycin
disintegrant
Prior art date
Application number
PE2002000948A
Other languages
Spanish (es)
Inventor
Barbara Haeberlin
Andrea Kramer
Silvia Heuerding
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9922916&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20030602(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PE20030602A1 publication Critical patent/PE20030602A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: a) UNA DISPERSION DE MACROLIDO SOLIDO SELECIONADO DE UN DERIVADO DE RAPAMICINA 40-O-(2-HIDROXI)ETIL-RAPAMICINA; b) UN DESINTEGRANTE; c) DE 1% A 5% DE DIOXIDO DE SILICIO COLOIDAL EN PESO. LA COMPOSICION ESTA EN FORMA DE TABLETA DISPERSABLE Y TIENE UN TIEMPO DE DESINTEGRACIN DE 90 SEGUNDOS/FK 506IT REFERS TO A PHARMACEUTICAL COMPOSITION INCLUDING: a) A DISPERSION OF MACROLIDE SOLID SELECTED FROM A DERIVATIVE OF RAPAMYCIN 40-O- (2-HYDROXY) ETHYL-RAPAMYCIN; b) A DISINTEGRANT; c) FROM 1% TO 5% OF COLLOIDAL SILICON DIOXIDE BY WEIGHT. THE COMPOSITION IS IN THE FORM OF A DISPERSIBLE TABLET AND HAS A DISINTEGRATION TIME OF 90 SECONDS / FK 506

PE2002000948A 2001-09-28 2002-09-26 PHARMACEUTICAL COMPOSITION INCLUDING A MACROLIDE PE20030602A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0123400.4A GB0123400D0 (en) 2001-09-28 2001-09-28 Organic compounds

Publications (1)

Publication Number Publication Date
PE20030602A1 true PE20030602A1 (en) 2003-08-27

Family

ID=9922916

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002000948A PE20030602A1 (en) 2001-09-28 2002-09-26 PHARMACEUTICAL COMPOSITION INCLUDING A MACROLIDE

Country Status (31)

Country Link
US (4) US20040254210A1 (en)
EP (2) EP2193788B1 (en)
JP (2) JP2005507897A (en)
KR (1) KR100626785B1 (en)
CN (3) CN101912392A (en)
AR (2) AR036643A1 (en)
AT (1) ATE485813T1 (en)
BR (2) BRPI0212922B1 (en)
CA (1) CA2458455C (en)
CO (1) CO5390072A1 (en)
CY (2) CY1111119T1 (en)
DE (1) DE60238131D1 (en)
DK (2) DK1432408T3 (en)
EC (1) ECSP024323A (en)
ES (2) ES2560106T3 (en)
GB (1) GB0123400D0 (en)
HK (2) HK1067036A1 (en)
HU (1) HU229991B1 (en)
IL (2) IL160498A0 (en)
MX (1) MXPA04002814A (en)
MY (1) MY150060A (en)
NO (1) NO333892B1 (en)
NZ (2) NZ531599A (en)
PE (1) PE20030602A1 (en)
PL (1) PL209704B1 (en)
PT (2) PT2193788E (en)
RU (1) RU2322970C2 (en)
SI (1) SI1432408T1 (en)
TW (1) TWI242449B (en)
WO (1) WO2003028705A1 (en)
ZA (1) ZA200401300B (en)

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