PE20011099A1 - COMPOSITIONS FOR THE TOPICAL DELIVERY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED OXIDATION - Google Patents

COMPOSITIONS FOR THE TOPICAL DELIVERY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED OXIDATION

Info

Publication number
PE20011099A1
PE20011099A1 PE2001000151A PE2001000151A PE20011099A1 PE 20011099 A1 PE20011099 A1 PE 20011099A1 PE 2001000151 A PE2001000151 A PE 2001000151A PE 2001000151 A PE2001000151 A PE 2001000151A PE 20011099 A1 PE20011099 A1 PE 20011099A1
Authority
PE
Peru
Prior art keywords
active agent
compositions
acid
pharmaceutically active
topical delivery
Prior art date
Application number
PE2001000151A
Other languages
Spanish (es)
Inventor
Jeffrey Warren Clymer
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of PE20011099A1 publication Critical patent/PE20011099A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/51—Chelating agents

Abstract

SE REFIERE A UNA COMPOSICION DE USO TOPICO QUE COMPRENDE: a)DE 1% A 50% DE UN FOSFOLIPIDO INSATURADO, PARCIALMENTE SATURADO COMO LECITINA, FOSFATIDILCOLINA, FOSFATIDILETANOLAMINA, FOSFATIDILSERINA, FOSFATIDILINOSITOL, ACIDO FOSFATIDICIO, ESFINGOMIELINAS; b)DE 0,01% A 10% DE UN AGENTE ACTIVO; c)DE 0,01% A 0,5% DE UN AGENTE QUELANTE COMO ACIDO ETILENDIAMINOTETRAACETICO, EDETATO DE SODIO, HEXAMETAFOSFATO, ACIDO GENTISICO, ENTRE OTROS; d)UN ANTIOXIDANTE COMO ACIDO BENCENOSULFONICO, 4-[(3-(3,5-BIS(1,1-DIMETILETIL)-4-HIDROXIFENIL)-1-OXOPROPIL)AMINO] SAL MONOSODICA, ACIDO ASCORBICO, PALMITATO DE ASCORBILO, HIDROXIANISOL, ENTRE OTROS. LA OXIDACION DE COMPOSICIONES QUE TIENE MAS DE 1% EN PESO DE FOSFOLIPIDO Y UN AGENTE ACTIVO SE PUEDE REDUCIR O PREVENIR MEDIANTE ADICION DE QUELANTEIT REFERS TO A COMPOSITION FOR TOPICAL USE THAT INCLUDES: a) FROM 1% TO 50% OF AN UNSATURATED PHOSPHOLIPID, PARTIALLY SATURATED SUCH AS LECITHIN, PHOSPHATIDYLCHOLINE, PHOSPHATIDYLETHANOLAMINE, PHOSPHATIDYLSERINE, PHOSPHATIDYLINOSITOLINE, PHOSPHATIDYLINOSITOLINE; b) FROM 0.01% TO 10% OF AN ACTIVE AGENT; c) FROM 0.01% TO 0.5% OF A CHELATING AGENT SUCH AS ETHYLENEDIAMINOTETRAACETIC ACID, SODIUM EDETATE, HEXAMETHOSPHATE, GENTISIC ACID, AMONG OTHERS; d) AN ANTIOXIDANT SUCH AS BENZENOSULPHONIC ACID, 4 - [(3- (3,5-BIS (1,1-DIMETHYLETHYL) -4-HYDROXYPHENYL) -1-OXOPROPYL) AMINO] MONOSODIUM SALT, ASCORBIC ACID, ASCORBYL PALMITATE, HYDROXYSOL , AMONG OTHERS. THE OXIDATION OF COMPOSITIONS THAT HAVE MORE THAN 1% BY WEIGHT OF PHOSPHOLIPID AND AN ACTIVE AGENT CAN BE REDUCED OR PREVENTED BY ADDITION OF CHELANT

PE2001000151A 2000-02-14 2001-02-12 COMPOSITIONS FOR THE TOPICAL DELIVERY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED OXIDATION PE20011099A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50434200A 2000-02-14 2000-02-14
US50379300A 2000-02-14 2000-02-14

Publications (1)

Publication Number Publication Date
PE20011099A1 true PE20011099A1 (en) 2001-11-23

Family

ID=27054619

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2001000151A PE20011099A1 (en) 2000-02-14 2001-02-12 COMPOSITIONS FOR THE TOPICAL DELIVERY OF A PHARMACEUTICALLY ACTIVE AGENT THAT HAS REDUCED OXIDATION

Country Status (4)

Country Link
AU (1) AU2001236997A1 (en)
CO (1) CO5261580A1 (en)
PE (1) PE20011099A1 (en)
WO (1) WO2001060337A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005022616D1 (en) * 2004-12-22 2010-09-09 Basf Se MEDIUM AGAINST RADICALS
KR20080099279A (en) 2006-02-24 2008-11-12 말린크로트, 인코포레이티드 Bifunctional resorcinol, thioresorcinol, and dithioresorcinol derivative metal chelating conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797285A (en) * 1985-12-06 1989-01-10 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Lipsome/anthraquinone drug composition and method
CA1283864C (en) * 1986-08-11 1991-05-07 Richard H. Roydhouse Body lubricating and cleansing fluid
DE4201527A1 (en) * 1992-01-21 1993-07-22 Knoll Ag LECITHIN SOLUTIONS WITH LEVEMOPAMIL

Also Published As

Publication number Publication date
CO5261580A1 (en) 2003-03-31
WO2001060337A1 (en) 2001-08-23
AU2001236997A1 (en) 2001-08-27

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Legal Events

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