PE20010665A1 - A PHARMACEUTICAL COMPOSITION OF DROSPIRENONE AND ETHINYLESTRADIOL TO BE USED AS A CONTRACEPTIVE - Google Patents

A PHARMACEUTICAL COMPOSITION OF DROSPIRENONE AND ETHINYLESTRADIOL TO BE USED AS A CONTRACEPTIVE

Info

Publication number
PE20010665A1
PE20010665A1 PE2000000895A PE0008952000A PE20010665A1 PE 20010665 A1 PE20010665 A1 PE 20010665A1 PE 2000000895 A PE2000000895 A PE 2000000895A PE 0008952000 A PE0008952000 A PE 0008952000A PE 20010665 A1 PE20010665 A1 PE 20010665A1
Authority
PE
Peru
Prior art keywords
ethinylestradiol
drospirenone
pharmaceutical composition
composition
contraceptive
Prior art date
Application number
PE2000000895A
Other languages
Spanish (es)
Inventor
Wolfgang Heil
Ralph Lipp
Jurgen Hilmann
Renate Heithecker
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8240592&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20010665(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Ag filed Critical Schering Ag
Publication of PE20010665A1 publication Critical patent/PE20010665A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: a)UN AGENTE ACTIVO 6ß,7ß; 15ß,16ß-DIMETILEN-3-OXO-17O-PREGN-4-EN-21, 17-CARBOLACTONA (DROSPIRENONA, UTILIZANDOSE 2mg A 4mg; b)17O-ETINILESTRADIOL (ETINILESTRADIOL) UTILIZANDOSE 0,01 mg A 0,05mg; c)EXCIPIENTES QUE PROMUEVEN LA DISOLUCION RAPIDA DE LOS AGENTES ACTIVOS; LA COMPOSICION SE CARACTERIZA PORQUE LOS AGENTES SE ENCUENTRAN EN FORMA MICRONIZADA O PULVERIZADA EN UNA SOLUCION SOBRE PARTICULAS DE SOPORTE INERTE, EL 70% DE LAS SUSTANCIAS ACTIVAS ES LIBERADA DENTRO DE LOS 30 MINUTOS DESDE LA ADMINISTRACION DE LA MISMA. LA COMPOSICION PUEDE SER UTIL PARA INHIBIR LA OVULACION, TRATAR TRASTORNOS INDUCIDOS POR ANDROGENOS COMO ACNEIT REFERS TO A PHARMACEUTICAL COMPOSITION THAT INCLUDES: a) AN ACTIVE AGENT 6ß, 7ß; 15ß, 16ß-DIMETHYLENE-3-OXO-17O-PREGN-4-EN-21, 17-CARBOLACTONE (DROSPIRENONE, USING 2mg TO 4mg; b) 17O-ETHINYLESTRADIOL (ETHINYLESTRADIOL) USING 0.01mg TO 0.05mg; c) EXCIPIENTS THAT PROMOTE THE RAPID DISSOLUTION OF THE ACTIVE AGENTS; THE COMPOSITION IS CHARACTERIZED BECAUSE THE AGENTS ARE IN MICRONIZED OR POWDERED FORM IN A SOLUTION ON INERT SUPPORT PARTICLES, 70% OF THE ACTIVE SUBSTANCES ARE RELEASED WITHIN 30 MINUTES FROM THE ADMINISTRATION OF THE SAME. THE COMPOSITION MAY BE USEFUL TO INHIBIT OVULATION, TREAT ANDROGEN-INDUCED DISORDERS SUCH AS ACNE

PE2000000895A 1999-08-31 2000-08-31 A PHARMACEUTICAL COMPOSITION OF DROSPIRENONE AND ETHINYLESTRADIOL TO BE USED AS A CONTRACEPTIVE PE20010665A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99202826 1999-08-31

Publications (1)

Publication Number Publication Date
PE20010665A1 true PE20010665A1 (en) 2001-06-19

Family

ID=8240592

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000000895A PE20010665A1 (en) 1999-08-31 2000-08-31 A PHARMACEUTICAL COMPOSITION OF DROSPIRENONE AND ETHINYLESTRADIOL TO BE USED AS A CONTRACEPTIVE

Country Status (6)

Country Link
CN (1) CN1879632A (en)
AR (2) AR025443A1 (en)
CO (1) CO5200771A1 (en)
EC (1) ECSP003721A (en)
PE (1) PE20010665A1 (en)
ZA (2) ZA200201668B (en)

Also Published As

Publication number Publication date
CO5200771A1 (en) 2002-09-27
AR043470A2 (en) 2005-07-27
ZA200404083B (en) 2006-02-22
CN1879632A (en) 2006-12-20
AR025443A1 (en) 2002-11-27
ECSP003721A (en) 2002-05-23
ZA200201668B (en) 2004-06-24

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