PE20010576A1 - USE OF A COMBINATION OF A NON-SEDATING ANTIHISTAMINE WITH AN EXPECTORANT TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH COUGH - Google Patents

USE OF A COMBINATION OF A NON-SEDATING ANTIHISTAMINE WITH AN EXPECTORANT TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH COUGH

Info

Publication number
PE20010576A1
PE20010576A1 PE2000000839A PE0008392000A PE20010576A1 PE 20010576 A1 PE20010576 A1 PE 20010576A1 PE 2000000839 A PE2000000839 A PE 2000000839A PE 0008392000 A PE0008392000 A PE 0008392000A PE 20010576 A1 PE20010576 A1 PE 20010576A1
Authority
PE
Peru
Prior art keywords
combination
cough
expectorant
inflammatory conditions
treat allergic
Prior art date
Application number
PE2000000839A
Other languages
Spanish (es)
Inventor
Lugo Sergio Rolando Ulloa
Ramos Jose De Jesus Villacampa
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of PE20010576A1 publication Critical patent/PE20010576A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE AL USO DE UNA COMBINACION DE: a)DE 5mg A 15mg DE UN ANTIHISTAMINICO NO SEDANTE TAL COMO LORATADINA; b)DE 30mg A 90mg DE UN EXPECTORANTE TAL COMO AMBROXOL. LA COMBINACION PROVEE ALREDEDOR DE 0.1mg/kg A 0.3mg/kg DE LORATADINA AL DIA EN DOSIS INDIVIDUALES O DIVIDIDAS Y DE O.5mg/kg A 2.0mg/kg DE AMBROXOL AL DIA EN DOSIS INVIVIDUALES O DIVIDIDAS. LA COMBINACION PUEDE SER UTIL PARA TRATAR O PREVENIR CONDICIONES ALERGICAS O INFLAMATORIAS CON TOS TAL COMO RINITIS ALERGICA ASOCIADA CON TOS, ASMA BRONQUIAL, BRONQUITIS, SINUSITIS, OTITIS, NEUMONIAIT REFERS TO THE USE OF A COMBINATION OF: a) FROM 5mg TO 15mg OF A NON-SEDATING ANTIHISTAMINIC SUCH AS LORATADINE; b) FROM 30mg TO 90mg OF AN EXPECTORANT SUCH AS AMBROXOL. THE COMBINATION PROVIDES ABOUT 0.1mg / kg TO 0.3mg / kg OF LORATADINE PER DAY IN INDIVIDUAL OR DIVIDED DOSES AND O.5mg / kg TO 2.0mg / kg OF AMBROXOL PER DAY IN INVIVIDUAL OR DIVIDED DOSES. THE COMBINATION MAY BE USEFUL TO TREAT OR PREVENT ALLERGIC OR INFLAMMATORY CONDITIONS WITH COUGH SUCH AS ALLERGIC RHINITIS ASSOCIATED WITH COUGH, BRONCHIAL ASTHMA, BRONCHITIS, SINUSITIS, OTITIS, PNEUMONIA

PE2000000839A 2000-03-30 2000-08-17 USE OF A COMBINATION OF A NON-SEDATING ANTIHISTAMINE WITH AN EXPECTORANT TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH COUGH PE20010576A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19331000P 2000-03-30 2000-03-30

Publications (1)

Publication Number Publication Date
PE20010576A1 true PE20010576A1 (en) 2001-05-08

Family

ID=22713096

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000000839A PE20010576A1 (en) 2000-03-30 2000-08-17 USE OF A COMBINATION OF A NON-SEDATING ANTIHISTAMINE WITH AN EXPECTORANT TO TREAT ALLERGIC AND INFLAMMATORY CONDITIONS WITH COUGH

Country Status (13)

Country Link
CN (1) CN1422162A (en)
AR (1) AR025308A1 (en)
AU (2) AU2001247867B2 (en)
BR (1) BR0003648A (en)
CO (1) CO5200779A1 (en)
CR (1) CR6232A (en)
NZ (1) NZ520826A (en)
PA (1) PA8500101A1 (en)
PE (1) PE20010576A1 (en)
SG (1) SG96611A1 (en)
TW (1) TWI243671B (en)
WO (1) WO2001074341A2 (en)
ZA (1) ZA200102605B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005123052A1 (en) * 2004-06-18 2005-12-29 Jiangsu Hengrui Medicine Co., Ltd. Drug composition containing ambroxol and erdosteine or acetylcysteine
CN1323662C (en) * 2004-06-18 2007-07-04 江苏恒瑞医药股份有限公司 Pharmaceutical composition containing ambroxol and erdosteine or acetylcysteine and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552899A (en) * 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4783465A (en) * 1984-04-09 1988-11-08 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4829064A (en) * 1987-06-08 1989-05-09 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
BR9407414A (en) * 1993-09-07 1996-11-12 Procter & Gamble Compositions containing a non-steroidal propionic acid anti-inflammatory agent amino acid salt and at least one decongestant an expectorant an antihistamine and an antitussive
US6160020A (en) * 1996-12-20 2000-12-12 Mcneill-Ppc, Inc. Alkali metal and alkaline-earth metal salts of acetaminophen

Also Published As

Publication number Publication date
AR025308A1 (en) 2002-11-20
TWI243671B (en) 2005-11-21
WO2001074341A2 (en) 2001-10-11
BR0003648A (en) 2002-01-02
AU4786701A (en) 2001-10-15
CR6232A (en) 2008-12-01
CN1422162A (en) 2003-06-04
PA8500101A1 (en) 2002-09-17
ZA200102605B (en) 2001-10-03
WO2001074341A3 (en) 2002-05-16
AU2001247867B2 (en) 2005-09-01
NZ520826A (en) 2004-07-30
CO5200779A1 (en) 2002-09-27
SG96611A1 (en) 2003-06-16

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