PE20001070A1 - METHODS AND COMPOSITIONS TO TREAT SINUSITIS, OTITIS MEDIA AND OTHER RELATED DISORDERS USING ANTIHISTAMINES - Google Patents

METHODS AND COMPOSITIONS TO TREAT SINUSITIS, OTITIS MEDIA AND OTHER RELATED DISORDERS USING ANTIHISTAMINES

Info

Publication number
PE20001070A1
PE20001070A1 PE1999000911A PE00091199A PE20001070A1 PE 20001070 A1 PE20001070 A1 PE 20001070A1 PE 1999000911 A PE1999000911 A PE 1999000911A PE 00091199 A PE00091199 A PE 00091199A PE 20001070 A1 PE20001070 A1 PE 20001070A1
Authority
PE
Peru
Prior art keywords
otitis media
antihistamines
compositions
methods
treat sinusitis
Prior art date
Application number
PE1999000911A
Other languages
Spanish (es)
Inventor
Alan G Harris
Richard R Lorber
Melvyn R Danzig
Domenic G Iezzoni
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of PE20001070A1 publication Critical patent/PE20001070A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE a)UNA ANTIHISTAMINA ANTICOLINERGICA DE FORMULA 1, LORATADINA, DESCARBOETOXILORATADINA; DONDE X ES HALOGENO, H; Y ES H, COOR1 O SO2R2; R1 ES ALQUILO, CICLOALQUILO, ALQUENILO, ARILO, HETEROCICLO; R2 ES CICLOALQUILO, ARILO; UTILIZANDOSE 2,5 mg A 20 mg POR DOSIS; b)UN PORTADOR FARMACEUTICAMENTE ACEPTABLE TAL COMO LACTOSA, SUCROSA, AZUCAR, CELULOSA, ESTEARATO DE MAGNESIO, FOSFATO DICALCICO, SULFATO DE CALCIO, MANITOL, ALCOHOL ETILICO; c)DESCONGESTIVO TAL COMO PSEUDOEFEDRINA; d)UN SUPRESOR DE TOS TAL COMO DEXTROMETORFANO; e)UN EXPECTORANTE TAL COMO GUAIFENASINA; f)UN ESTEROIDE NASAL TAL COMO FUROATO DE MOMETASONA; g)UN ANALGESICO NO NARCOTICO TAL COMO ACETAMINOFENO. LA COMPOSICION PUEDE SER UTIL PARA TRATAR SINUSITIS, OTITIS MEDIA NO INFECCIOSAIT REFERS TO A PHARMACEUTICAL COMPOSITION INCLUDING a) AN ANTICHOLINERGIC ANTIHISTAMINE OF FORMULA 1, LORATADINE, DESCARBOETOXYLORATADINE; WHERE X IS HALOGEN, H; Y IS H, COOR1 OR SO2R2; R1 IS ALKYL, CYCLOALKYL, ALKENYL, ARYL, HETEROCYCLE; R2 IS CYCLOALKYL, ARYL; USING 2.5 mg TO 20 mg PER DOSE; b) A PHARMACEUTICALLY ACCEPTABLE CARRIER SUCH AS LACTOSE, SUCROSA, SUGAR, CELLULOSE, MAGNESIUM STEARATE, DICALCICO PHOSPHATE, CALCIUM SULPHATE, MANNITOL, ETHYL ALCOHOL; c) DECONGESTIVE SUCH AS PSEUDOEPHEDRINE; d) A COUGH SUPPRESSOR SUCH AS DEXTROMETORPHANE; e) AN EXPECTORANT SUCH AS GUAIFENASIN; f) A NASAL STEROID SUCH AS MOMETASONE FUROATE; g) A NON-NARCOTIC ANALGESIC SUCH AS ACETAMINOPHENE. THE COMPOSITION MAY BE USEFUL TO TREAT SINUSITIS, NON-INFECTIOUS OTITIS MEDIA

PE1999000911A 1998-09-10 1999-09-09 METHODS AND COMPOSITIONS TO TREAT SINUSITIS, OTITIS MEDIA AND OTHER RELATED DISORDERS USING ANTIHISTAMINES PE20001070A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15084298A 1998-09-10 1998-09-10

Publications (1)

Publication Number Publication Date
PE20001070A1 true PE20001070A1 (en) 2000-10-19

Family

ID=22536220

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1999000911A PE20001070A1 (en) 1998-09-10 1999-09-09 METHODS AND COMPOSITIONS TO TREAT SINUSITIS, OTITIS MEDIA AND OTHER RELATED DISORDERS USING ANTIHISTAMINES

Country Status (6)

Country Link
AR (1) AR022378A1 (en)
AU (1) AU6018899A (en)
CO (1) CO5271713A1 (en)
PA (1) PA8481801A1 (en)
PE (1) PE20001070A1 (en)
WO (1) WO2000015226A1 (en)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4829064A (en) * 1987-06-08 1989-05-09 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4990535A (en) * 1989-05-03 1991-02-05 Schering Corporation Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
US5314697A (en) * 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
US5595997A (en) * 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
EP0780127A1 (en) * 1995-12-19 1997-06-25 The Procter & Gamble Company A nasal spray containing a steroid and a antihistamine
AU732671B2 (en) * 1996-02-08 2001-04-26 Merck & Co., Inc. Method of treatment and pharmaceutical composition
CO4910128A1 (en) * 1996-10-31 2000-04-24 Schering Corp ASTHMA TREATMENT AND USEFUL COMPOUNDS FOR THIS COMBINATION TREATMENT AND A KIT OF THIS COMBINATION

Also Published As

Publication number Publication date
AR022378A1 (en) 2002-09-04
WO2000015226A1 (en) 2000-03-23
AU6018899A (en) 2000-04-03
CO5271713A1 (en) 2003-04-30
PA8481801A1 (en) 2000-09-29

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