PE14795A1 - POLYMERIC MATRIX OF ETHYLENE POLYCARBONATE AND ITS USE IN PHARMACEUTICAL COMPOSITIONS - Google Patents

POLYMERIC MATRIX OF ETHYLENE POLYCARBONATE AND ITS USE IN PHARMACEUTICAL COMPOSITIONS

Info

Publication number
PE14795A1
PE14795A1 PE1994249355A PE24935594A PE14795A1 PE 14795 A1 PE14795 A1 PE 14795A1 PE 1994249355 A PE1994249355 A PE 1994249355A PE 24935594 A PE24935594 A PE 24935594A PE 14795 A1 PE14795 A1 PE 14795A1
Authority
PE
Peru
Prior art keywords
polymeric matrix
pharmaceutical compositions
units
ethylene carbonate
ethylene
Prior art date
Application number
PE1994249355A
Other languages
Spanish (es)
Inventor
Siegfried Bantle
David Bodmer
Murat Acemoglu
Salvatore Cammisuli
Peter Hiestand
Fritz Nimmerfall
Georg Stoll
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of PE14795A1 publication Critical patent/PE14795A1/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA DE LIBERACION PROLONGADA EN FORMA DE MICROPARTICULAS O DE UN IMPLANTE, QUE COMPRENDE: A) UN COMPUESTO ACTIVO, DE PREFERENCIA UNA INTERLEUCINA QUE PUEDE SER UTIL EN EL TRATAMIENTO DE CONDICIONES INFLAMATORIAS INDUCIDAS POR PATOGENOS, DESMIELINACION, CHOQUE SEPTICO; B) UNA MATRIZ POLIMERICA BIODEGRADABLE FORMADA POR UNIDADES DE CARBONATO DE ETILENO DE FORMULA -(-C(O)-O-CH2-CH2O-)- Y POR UNIDADES DE OXIDO DE ETILENO DE FORMULA -(-CH2-CH2-O-)-; QUE TIENE UN CONTENIDO DE CARBONATO DE ETILENO DE 70% A 100% EN MOL, UNA VISCOSIDAD INTRINSECA DE 0,4 dl/g A 4,0 dl/g EN CLOROFORMO Y UNA TEMPERATURA DE TRANSICION VITREA DESDE 15°C A 50°C; DICHA MATRIZ SE DEGRADA POR EROSION SUPERFICIAL NO HIDROLITICAIT REFERS TO A PHARMACEUTICAL COMPOSITION OF PROLONGED RELEASE IN THE FORM OF MICROPARTICLES OR AN IMPLANT, WHICH INCLUDES: A) AN ACTIVE COMPOUND, PREFERRED AN INTERLEUKIN THAT MAY BE USEFUL IN THE TREATMENT OF INFLAMMATORY CONDITIONS, SEIZED BY PATHOGENES; B) A BIODEGRADABLE POLYMERIC MATRIX FORMED BY UNITS OF FORMULA ETHYLENE CARBONATE - (- C (O) -O-CH2-CH2O -) - AND BY UNITS OF FORMULA ETHYLENE OXIDE - (- CH2-CH2-O-) -; WHICH HAS AN ETHYLENE CARBONATE CONTENT OF 70% TO 100% IN MOL, AN INTRINSIC VISCOSITY OF 0.4 dl / g TO 4.0 dl / g IN CHLOROFORM AND A GLASS TRANSITION TEMPERATURE FROM 15 ° C TO 50 ° C; THE MATRIX IS DEGRADED BY NON-HYDROLYTIC SURFACE EROSION

PE1994249355A 1993-08-27 1994-08-26 POLYMERIC MATRIX OF ETHYLENE POLYCARBONATE AND ITS USE IN PHARMACEUTICAL COMPOSITIONS PE14795A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939317822A GB9317822D0 (en) 1993-08-27 1993-08-27 Organic compounds

Publications (1)

Publication Number Publication Date
PE14795A1 true PE14795A1 (en) 1995-06-08

Family

ID=10741118

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1994249355A PE14795A1 (en) 1993-08-27 1994-08-26 POLYMERIC MATRIX OF ETHYLENE POLYCARBONATE AND ITS USE IN PHARMACEUTICAL COMPOSITIONS

Country Status (4)

Country Link
GB (1) GB9317822D0 (en)
PE (1) PE14795A1 (en)
RU (1) RU2190634C2 (en)
ZA (1) ZA946536B (en)

Also Published As

Publication number Publication date
GB9317822D0 (en) 1993-10-13
RU2190634C2 (en) 2002-10-10
ZA946536B (en) 1996-02-26

Similar Documents

Publication Publication Date Title
ATE527000T1 (en) BIODEGRADABLE POLYMER SYSTEM
PT1075258E (en) NEW FATAL ANALOGS FOR THE TREATMENT OF OBESITY
CO5440227A1 (en) ANTIHELMITIC AND INJECTABLE COMPOSITION IMPROVED GROWTH
ATE166906T1 (en) REINFORCED BIODEGRADABLE POLYMER
KR920009293A (en) Aqueous composition
CA2247848A1 (en) Nitric oxide donors capable of reducing toxicity from drugs
KR950702419A (en) INJECTION AND INJECTION KIT CONTAINING OMEPRAZOLE AND ITS ANALOGS Containing Omeprazole and Its Homologs
DE60114209D1 (en) MEDICAMENT FORMING WITH A CELL REGULATING FACTOR AND / OR A PROMOTER FOR PROLIFERING CELLS
BR9916881A (en) Methods for treating ovarian cancer, poly (phosphoester) compositions and biodegradable articles
BR9915469A (en) Compositions of propylene polycrystalline copolymers having improved sealing and optical properties and reduced solubility
PT1589949E (en) Stabilized lyophilized compositions comprising tissue factor pathway inhibitor or tissue factor pathway inhibitor variants
NO996042L (en) Biocidal salts with organic acids of a polymeric biguanide
PE20030402A1 (en) PRODUCTS FOR THE ARM WITH WATER LOCKING COMPONENTS
DK1284943T3 (en) Extrusion of ceramic compositions and ceramic compositions therefor
BRPI0410133A (en) molded or extruded articles comprising short annealing cycle polyhydroxyalkanoate copolymer compositions
ES2095658T3 (en) COMPOSITION FOR THE CONTROLLED RELEASE OF AN ACTIVE SUBSTANCE AND METHOD FOR THE PREPARATION OF SUCH COMPOSITION.
AR009376A1 (en) PHARMACEUTICAL COMPOSITION COMPRISING A TIAZOL DERIVATIVE FOR THE PREVENTION AND TREATMENT OF DISEASES CAUSED BY THE ABNORMAL PRODUCTION OF CYTOKINES AND / OR THE ACCELERATION OF THE ADHESION OF NEUTROPHILS AND / OR THE ABNORMAL PRODUCTION OF TNF-ALPHA AND THE USE OF DICH-ALPHA TIAZOL FOR LA PREPARAC
ATE329959T1 (en) ANTISTATIC COMPOSITION
ATE420918T1 (en) OXYGEN BARRIER REFORMULATIONS
ES2190655T3 (en) USE OF POLYESTER RESINS FOR THE PRODUCTION OF ARTICLES THAT HAVE GOOD BARRIER PROPERTIES REGARDING WATER VAPOR.
BR9406414A (en) Compositions in the form of solid process solutions to prepare the same application of the same and granular powders tablets pellets suppositories and injectable solutions from them
PE14795A1 (en) POLYMERIC MATRIX OF ETHYLENE POLYCARBONATE AND ITS USE IN PHARMACEUTICAL COMPOSITIONS
DK0715646T3 (en) surfactants
BR9808722A (en) Pharmaceutical compositions of tizoxanide and nitazoxanide
HK1081213A1 (en) Compositions comprising polycarbonates

Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed