PA8593701A1 - [4- (3-AMINOMETILPHENYL) PIPERIDIN-1-IL] - [5- (2-FLUOROPHENYL-ETINYL) FURAN-2-IL] -METANOMA AS A MASTOCYT TRIPTASE INHIBITOR - Google Patents
[4- (3-AMINOMETILPHENYL) PIPERIDIN-1-IL] - [5- (2-FLUOROPHENYL-ETINYL) FURAN-2-IL] -METANOMA AS A MASTOCYT TRIPTASE INHIBITORInfo
- Publication number
- PA8593701A1 PA8593701A1 PA20038593701A PA8593701A PA8593701A1 PA 8593701 A1 PA8593701 A1 PA 8593701A1 PA 20038593701 A PA20038593701 A PA 20038593701A PA 8593701 A PA8593701 A PA 8593701A PA 8593701 A1 PA8593701 A1 PA 8593701A1
- Authority
- PA
- Panama
- Prior art keywords
- triptase
- inhibitor
- metanoma
- mastocyt
- aminometilphenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
LA PRESENTE INVENCION SE EXTIENDE AL COMPUESTO DE FORMULA (I): O UN PROFARMACO, SAL FARMACEUTICAMENTE ACEPTABLE, O SOLVATO DE DICHO COMPUESTO; A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UNA CANTIDAD FARMACEUTICAMENTE EFECTIVA DEL COMPUESTO DE FORMULA (I), Y UN VEHICULO FARMACEUTICAMENTE ACEPTABLE; AL USO DE UN COMPUESTO DE FORMULA (I) COMO UN INHIBIDOR DE TRIPTASA, QUE COMPRENDE INTRODUCIR EL COMPUESTO EN UNA COMPOSICION QUE COMPRENDE TRIPTASA.THE PRESENT INVENTION EXTENDS TO THE FORMULA COMPOUND (I): OR A PROFARMACO, PHARMACEUTICALLY ACCEPTABLE SALT, OR SOLVATE OF SUCH COMPOUND; TO A PHARMACEUTICAL COMPOSITION THAT INCLUDES A PHARMACEUTICALLY EFFECTIVE AMOUNT OF THE FORMULA COMPOUND (I), AND A PHARMACEUTICALLY ACCEPTABLE VEHICLE; TO THE USE OF A FORMULA COMPOUND (I) AS A TRIPTASE INHIBITOR, WHICH INCLUDES INTRODUCING THE COMPOUND IN A COMPOSITION THAT INCLUDES TRIPTASE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43653402P | 2002-12-26 | 2002-12-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8593701A1 true PA8593701A1 (en) | 2005-05-24 |
Family
ID=23732791
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20038593701A PA8593701A1 (en) | 2002-12-26 | 2003-12-23 | [4- (3-AMINOMETILPHENYL) PIPERIDIN-1-IL] - [5- (2-FLUOROPHENYL-ETINYL) FURAN-2-IL] -METANOMA AS A MASTOCYT TRIPTASE INHIBITOR |
Country Status (9)
Country | Link |
---|---|
US (1) | US20040192734A1 (en) |
AR (1) | AR042674A1 (en) |
AU (1) | AU2003301137A1 (en) |
GB (1) | GB0308613D0 (en) |
PA (1) | PA8593701A1 (en) |
PE (1) | PE20040931A1 (en) |
TW (1) | TW200508227A (en) |
UY (1) | UY28152A1 (en) |
WO (1) | WO2004060884A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1571150A1 (en) * | 2004-03-02 | 2005-09-07 | Aventis Pharma Deutschland GmbH | Process for the preparation of tryptase inhibitors |
WO2006044133A1 (en) * | 2004-09-24 | 2006-04-27 | Axys Pharmaceuticals, Inc. | Active ketone inhibitors of tryptase |
JP2011504499A (en) | 2007-11-21 | 2011-02-10 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Spiropiperidine for use as a tryptase inhibitor |
CN111568894B (en) * | 2020-05-18 | 2021-07-27 | 中国医学科学院肿瘤医院 | Use of 2- (ethylaminomethyl) -5- (phenyl) furan for the preparation of a medicament for inhibiting TLR7/8 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2409827C (en) * | 2000-05-22 | 2010-06-01 | Aventis Pharmaceuticals Products Inc. | Arylmethylamine derivatives for use as tryptase inhibitors |
-
2003
- 2003-04-15 GB GBGB0308613.9A patent/GB0308613D0/en not_active Ceased
- 2003-12-18 WO PCT/US2003/040653 patent/WO2004060884A1/en not_active Application Discontinuation
- 2003-12-18 AU AU2003301137A patent/AU2003301137A1/en not_active Abandoned
- 2003-12-22 US US10/743,618 patent/US20040192734A1/en not_active Abandoned
- 2003-12-23 PA PA20038593701A patent/PA8593701A1/en unknown
- 2003-12-25 TW TW092136784A patent/TW200508227A/en unknown
- 2003-12-26 UY UY28152A patent/UY28152A1/en unknown
- 2003-12-29 AR ARP030104855A patent/AR042674A1/en unknown
-
2004
- 2004-01-05 PE PE2004000016A patent/PE20040931A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2003301137A1 (en) | 2004-07-29 |
UY28152A1 (en) | 2004-07-30 |
TW200508227A (en) | 2005-03-01 |
AR042674A1 (en) | 2005-06-29 |
GB0308613D0 (en) | 2003-05-21 |
US20040192734A1 (en) | 2004-09-30 |
PE20040931A1 (en) | 2004-12-24 |
WO2004060884A1 (en) | 2004-07-22 |
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