PA8488001A1 - 3-AZABICICLO DERIVATIVES [3.1.0.] USEFUL HEXANE IN THERAPY - Google Patents

3-AZABICICLO DERIVATIVES [3.1.0.] USEFUL HEXANE IN THERAPY

Info

Publication number
PA8488001A1
PA8488001A1 PA19998488001A PA8488001A PA8488001A1 PA 8488001 A1 PA8488001 A1 PA 8488001A1 PA 19998488001 A PA19998488001 A PA 19998488001A PA 8488001 A PA8488001 A PA 8488001A PA 8488001 A1 PA8488001 A1 PA 8488001A1
Authority
PA
Panama
Prior art keywords
useful
azabiciclo
hexane
therapy
derivatives
Prior art date
Application number
PA19998488001A
Other languages
Spanish (es)
Inventor
Bernard Joseph Banks
Stephen Paul Gibson
Graham Lunn
Alan John Pettman
Robert James Crook
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9828485.4A external-priority patent/GB9828485D0/en
Priority claimed from GBGB9912425.7A external-priority patent/GB9912425D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of PA8488001A1 publication Critical patent/PA8488001A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/12—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

SE DESCRIBEN COMPUESTOS DE FORMULA (I), SUS SALES Y LOS PROFARMACOS DE LOS MISMOS, EN LOS QUE LOS SUSTITUYENTES SON COMO SE HAN DEFINIDO EN ESTE DOCUMENTO, COMO AGENTES DE UNION A OPIACEOS UTILES EN EL TRATAMIENTO DE AFECCIONES MEDIADAS POR OPIACEOS. TAMBIEN SE DESCRIBEN PROCEDIMIENTOS PARA PREPARAR TALES SUSTANCIAS.FORMULA COMPOUNDS (I), THEIR SALTS AND THE PROFARMS OF THE SAME ARE DESCRIBED, IN WHICH THE SUBSTITUTES ARE LIKE THEY HAVE BEEN DEFINED IN THIS DOCUMENT, AS AGENTS OF UNION TO USEFUL OPISONS IN THE TREATMENT OF CONDITIONS OPTIZED. PROCEDURES TO PREPARE SUCH SUBSTANCES ARE ALSO DESCRIBED.

PA19998488001A 1998-12-23 1999-12-23 3-AZABICICLO DERIVATIVES [3.1.0.] USEFUL HEXANE IN THERAPY PA8488001A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9828485.4A GB9828485D0 (en) 1998-12-23 1998-12-23 Compounds useful in therapy
GBGB9912425.7A GB9912425D0 (en) 1999-05-27 1999-05-27 Compounds useful in therapy

Publications (1)

Publication Number Publication Date
PA8488001A1 true PA8488001A1 (en) 2002-10-28

Family

ID=40257194

Family Applications (1)

Application Number Title Priority Date Filing Date
PA19998488001A PA8488001A1 (en) 1998-12-23 1999-12-23 3-AZABICICLO DERIVATIVES [3.1.0.] USEFUL HEXANE IN THERAPY

Country Status (10)

Country Link
KR (1) KR100504647B1 (en)
AR (1) AR035157A1 (en)
CO (1) CO5261495A1 (en)
IL (1) IL142697A (en)
MY (1) MY130771A (en)
PA (1) PA8488001A1 (en)
PE (1) PE20001318A1 (en)
PT (1) PT1140828E (en)
RS (1) RS50051B (en)
TN (1) TNSN99235A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2651857A1 (en) 2006-05-31 2007-12-06 F. Hoffmann-La Roche Ag Aryl-4-ethynyl-isoxazole derivatives

Also Published As

Publication number Publication date
PE20001318A1 (en) 2000-12-01
CO5261495A1 (en) 2003-03-31
AR035157A1 (en) 2004-05-05
KR20010086462A (en) 2001-09-12
PT1140828E (en) 2006-12-29
IL142697A (en) 2009-05-04
YU41501A (en) 2004-03-12
KR100504647B1 (en) 2005-07-29
RS50051B (en) 2008-11-28
TNSN99235A1 (en) 2005-11-10
MY130771A (en) 2007-07-31

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