OA16732A - Oil dispersion of sulfoximines for the control of insects. - Google Patents

Abstract

The invention relates to oil dispersions of sulfoximine insecticides, such as sulfoxaflor, and methods of using these dispersions to control insects such as whitefly.

Description

OIL DISPERSION OF SULFOXIMINES FOR

THE CONTROL OF INSECTS

PRIORITY CLAIM

This application claims the benefit of the filing date of United States Provisional Patent Application Serial No. 61/494,178, filed June 7, 2011, for Oil Dispersion of Sulfoximines for the Control of Insects.”

TECHNICAL FIELD

This invention relates generally to formulation of the active ingrédient [methyl(oxo) {1-[6trifluoromethyl)-3-pyridyl]ethyl}-D⁶-sulfanylidene]cyanamide and similar compounds dispersed in water-immiscible solvents.

BACKGROUND

Sulfoximines with insecticidal activity hâve widespread utility for the control of insect. One particularly useful sulfoximine in this regard is a compound called sulfoxaflor, which is its common name, [methyl(oxo){1 -[6-trifluoromethyl)-3-pyridyl]ethyl}-D^e-sulfanylidene]cyanamide, which is its IUPAC name, and A/-[methyloxido[1-[6-(trifluoromethyl)-3-pyridinyl]ethyl]-A'’sulfanylidenejcyanamide, which is its CAS Name. It has the following structure.

Despite the utility of sulfoximines, the ability of these compounds to efficiently control insect varies with a large number of parameters including, but not limited to, the species of insect to be controlled, the types of plant to be protected and the ambient conditions, such as température, humidity, hydration, length of day, biological diversity of the micro environment, and the like. Accordingly, there is a need for formulations of sulfoximines that extend the utility and/or increase the efficacy of these compounds. One object of the invention is to address this need.

-2DISCLOSURE

Some aspects of the invention include sulfoximines with insecticidal activity, such as sulfoxaflor, formulated into oil dispersion using water-immiscible solvents for the control of insects, Insects that can be controlled using these formulations include, but are not limited to, suckîng insects such as aphids. In some embodiments, the formulation may further include one or more of the following compounds: emulsifiers, coolants, dispersants, thickening agents, bactéricides, bacteriostats, antioxidants, ultra violet light absorbing molécules, and other agriculturally active ingrédients such as other insecticides, miticides, fungicides, herbicides, and the like.

Still other aspects of the invention include methods of controlling insect infestations by applying formulations that include sulfoximines, such as [methyl(oxo) [1-[6-trifluoromethyl)-3pyridyl]ethyl}-n⁶-sulfanylidene]cyanamide, formulated into oil dispersion using water-immiscible solvents by applying these formulations to areas adjacent to or susceptible to insect infestation.

MODE(S) FOR CARRYING OUT THE INVENTION

For the purposes of describing the principles of the novel technology, reference will now be made to the particular embodiments thereof, and spécifie language will be used to describe the same. It will, nevertheless, be understood that no limitation of the scope of the novel technology is thereby intended, such alterations, modifications, and further applications of the principles of the novel technology being contemplated as would normally occur to one skilled in the art to which the novel technology relates.

Pests, such as whiteflies of the genus Bemisia, are responsible for crop damage in many parts of world. Particularly damaging species include B. tabaci and B. argenifoliï. Whiteflies infect a wide variety of very important crop plants, such as beans, tomatoes, cassava, cotton, potatoes, and sweet potatoes. Historically, these insects hâve been especially problematic in the tropical and subtropical régions. These insects feed by inserting their mouthparts into the phloem of the plant and sucking water and nutrients from the plant, thereby depriving the plant of nutrients and reducing its turgor. Additionally, the wounds that they create in the plants from which they feed provide an avenue for viral infection. In fact, many very harmful plant viruses may hâve evolved an abilîty to exist in whitefly sécrétions as their presence there provides them with ready access to plants that they are able to infect.

Whiteflies, like many insects that infest crop plants, hâve demonstrated a remarkable abilîty to evolve résistance to frequently used insecticides. Accordingly, the introduction of sulfoximines, such as sulfoxaflor, with insecticidal activity towards these types of insects is a l ·

-3welcome addition to the ranks of compounds that can be used to treat infestations of these and other susceptible insects. For additional information on these insecticides, see, for example, U. S. Patent No. 7,687,634 issued on March 30, 2010.

In order to minimize the amount of insecticide that needs to be applied to a given area to control, rollback, contain, or prevent an infestation of damaging insects and thereby reduce the cost of using the insecticide, it may be useful to formulate the insecticide in a formulation that increases its ability to control the target insect. Additional design considérations that go into providing an insecticidal formulation with increased utility include its stability both in storage and after application, ease of dispersion, and rate of insect control.

Given the vast array of additives that can be combined with an insecticide to produce formulations of a new insecticide that has advantageous properties, the development of these formulations may require extensive, expensive and commercially risky investment in time and resources. Additionally, the complex interplay between agriculturally active ingrédients, other components in a given formulation as well the interplay between the various plant species and the insects that attack those plants make success in this field unlikely. Aspects of the invention disclosed herein include formulation of compounds, such as Sulfoxaflor, and water-immiscible components to create an Oil Dispersion (OD) of Sulfoxaflor in a suitable carrier.

Sulfoximines for use with the présent invention can be utilized in suffîcient amounts to provide insecticidal activity. According to a partîcular embodiment of the invention, about 10% to about 50% by weight of the total insecticidal formulation of sulfoximine can be used at any spécifie amount within the stated range. In another embodiment of the invention, about 12% to about 48% by weight of sulfoximine can be used at any spécifie amount within the stated range. In yet another embodiment, about 20% to about 40% of sulfoximine can be used at any spécifie amount within the stated range.

Various non-water-miscible solvents that can be used in these formulations include, but are not limited to, one or more petroleum distillâtes, such as; aromatic hydrocarbons derived from benzene, such as toluene, xylenes, other alkylated benzenes and the like, and naphthalene dérivatives, aliphatic hydrocarbons such as hexane, octane, cyclohexane, and the like, minerai oils from the aliphatic or îsoparaffinic sériés, and mixtures of aromatic and aliphatic hydrocarbons; halogenated aromatic or aliphatic hydrocarbons; vegetable, seed or animal oils such as soybean oil, râpe seed oil, olive oil, castor oil, sunflower seed oil, coconut oil, corn oil, cotton seed oil, linseed oil, palm oil, peanut oil, safflower oil, sesame oil, tung oil and the like, and CpCe mono-esters derived from vegetable, seed or animal oils; C^-Ce dialkyl amides of C_eC₂₀ saturated and unsaturated aliphatic carboxylîc acids, such as, N-N-dimethyl alkyl amide; C,C₁₂ esters of aromatic carboxylîc acids and dicarboxylic acids and Cî-C^ esters of aliphatic and

-4cyclo-aliphatic carboxylic acids; C₄-C₁₂ polyesters of dihydric, trihydric, or other lower polyalcohols such as, propylene glycol dioleate, di-octyl succinate, di-butyl adipate, di-octyl phthalate and the like.

These formulations may also include other additives as may be added to such compositions to increase their stability such as bactéricides and bacteriostats. Still other additives that may be added to the foundation include dyes, thickening agents, emulsifiers, defoamers, wetting agents, dispersants, and in some instance other agriculturally active ingrédients including, for example, other insecticides, or herbicides, miticides, fungicides and the like.

The formulations may include an emulsïfier in an amount from about 1% to about 30% by weight. Suitable emulsifiers include, but are not limited to, lecithin and modified lecithins, mono- and diglycerides, sorbitan monopalmitate, sorbitan monooleate, sorbitan monolaurate, polyoxyethylene-sorbitan monooleate, fatty acids, lipids, etc. The emulsifiers added to a formulation may provide or improve the émulsification properties of the composition. Emulsifiers can be used and may be selected from many products which are well known in the art including, but not limited to, sorbitan monolaurate (anhydrosorbitol stéarate, molecular formula C₂4l-UOe), ARLACEL 60, ARMOTAN MS, CRILL 3, CRILL K3, DREWSORB 60, DURTAN 60, EMSORB 2505, GLYCOMUL S, HODAG SMS, IONET S 60, LIPOSORB S, LIPOSORB S-20, MONTANE 60, MS 33, MS33F, NEWCOL 60, NIKKOL SS 30, NISSAN NONION SP 60, NONION SP 60, NONION SP 60R, RIKEMAL S 250, sorbitan c, sorbitan stéarate, SORBON 60, SORGEN 50, SPAN 55, AND SPAN 60. Still other sorbitan fatty acid ester that may be used in these formulations include, for example, sorbitan monopalmitate, sorbitan monostearate, sorbitan tristearate, sorbitan monooleate, sorbitan sesquioleate, sorbitan trioleate, sorbitan monooleate, sorbitan trioleate.

A variety of additives may be included in the formulations. These additives typically change and/or enhance the physical characteristics of the carrier material and are, therefore, suitable for designing compositions having spécifie requirements such as release rates, the amount of semiochemicals/attractants and/or repellents released, protection of the wax composition from various weather conditions, etc. These additional additives include, among others, plasticizers, volatility suppressants, antioxidants, lipids, various ultraviolet blockers and absorbers, or antimicrobiais, typically added in amounts from about 0.001% to about 10%, more typically between 0.1-5%, by weight.

Plasticizers, such as glycerin or soy oil that affect the physical properties of the composition and may extend its résistance to environmental destruction may also be added.

i’A > i

-5Antioxidants, such as vitamin E, BHA (butylated hydroxyanisole), BHT (butylated hydroxytoluene), and other antioxidants which protect the bioactive agent from dégradation, may be added to the formulation in amounts from about 0.1% to about 3%, by weight.

Ultraviolet blockers, such as beta-carotene or p-aminobenzoic acid that protect the bioactive agents from light dégradation may be added to the formulation in amounts ranging from about 1% to about 3%, by weight.

Antimicrobiais, such as potassium sorbate, nitrates, nitrites, and propylene oxide, which protect the bioactive agents from microbial destruction, may be also added to the formulation in amounts ranging from 0.1% to about 2% by weight.

The formulations of the présent invention may be applied in conjunction with one or more other agriculturally active ingrédients, such as other insecticides, fongicides, or herbicides to obtain control over a wider variety of insects, diseases and weeds. When used in conjunction with other agriculturally active ingrédients, the presentiy claimed compounds can be formulated with the other insecticides, or fongicides, or herbicides, tank mixed with the other insecticides or fongicides or herbicides, or applied sequentially with the other insecticides or fongicides or herbicides.

Some of the insecticides that can be employed beneficially in combination with the formulations of the présent invention include: antibiotic insecticides, such as allosamidîn and thuringiensin; macrocyclic lactone insecticides, such as spinosad, spinetoram, and other spinosyns including the 21-butenyl spinosyns and their dérivatives; avermectin insecticides, such as abamectin, doramectin, emamectin, eprinomectin, ivermectin and selamectin; milbemycin insecticides, such as lepimectin, milbemectin, milbemycin oxime and moxidectin; arsenical insecticides, such as calcium arsenate, copper acetoarsenite, copper arsenate, lead arsenate, potassium arsenite and sodium arsenite; biological Insecticides such as Bacillus popilliae, B. sphaericus, B. thuringiensis subsp. aizawai, B. thuringiensis subsp. kurstaki, B. thuringiensis subsp. tenebrionis, Beauveria bassiana, Cydia pomonella granulosis virus, Douglas fir tussock moth NPV, gypsy moth NPV, Helicoverpa zea NPV, Indian meal moth granulosis virus, Metarhizium anisopliae, Nosema locustae, Paecilomyces fumosoroseus, P. lilacinus, Photorhabdus luminescens, Spodoptera exigua NPV, trypsin modulating oostatic factor, Xenorhabdus nematophilus, and X. bovienii, plant incorporated protectant insecticides such as CrylAb, CrylAc, Cry1F, Cry1A.1O5, Cry2Ab2, Cry3A, mir Cry3A, Cry3Bb1, Cry34, Cry35, and VIP3A; botanical insecticides, such as anabasine, azadirachtin, d-limonene, nicotine, pyrethrins, cinerins, cinerin I, cinerin II, jasmolin I, jasmolin II, pyrethrin I, pyrethrin II, quassia, rotenone, ryania and sabadilla; carbamate insecticides such as bendiocarb and carbaryl; benzofuranyl methylcarbamate insecticides, such as benfuracarb, carbofuran,

-6carbosulfan, decarbofuran and furathiocarb; dimethylcarbamate insecticides dimitan, dimetilan, hyquincarb and pirimicarb; oxime carbamate insecticides, such as alanycarb, aldicarb, aldoxycarb, butocarboxim, butoxycarboxim, methomyl, nitrilacarb, oxamyl, tazimcarb, thiocarboxime, thiodicarb and thiofanox; phenyl methylcarbamate insecticides, such as allyxycarb, aminocarb, bufencarb, butacarb, carbanolate, cloethocarb, dicresyl, dioxacarb, EMPC, ethiofencarb, fenethacarb, fenobucarb, isoprocarb, methiocarb, metolcarb, mexacarbate, promacyl, promecarb, propoxur, trimethacarb, XMC and xylylcarb; dinitrophenol insecticides, such as dinex, dinoprop, dinosam and DNOC; fluorine insecticides, such as barium hexafluorosilicate, cryolite, sodium fluoride, sodium hexafluorosiiicate and sulfluramid; formamidine insecticides, such as amitraz, chlordimeform, formetanate and formparanate; fumigant insecticides, such as acrylonitrile, carbon disulfide, carbon tetrachloride, chloroform, chloropicrin, para-dichlorobenzene, 1,2-dichloropropane, ethyl formate, ethylene dibromide, ethylene dichloride, ethylene oxide, hydrogen cyanide, iodomethane, methyl bromide, methylchloroform, methylene chloride, naphthalene, phosphine, sulfuryl fluoride and tetrachloroethane; inorganic insecticides, such as borax, calcium polysulfide, copper oleate, mercurous chloride, potassium thiocyanate and sodium thiocyanate; chitin synthesis inhibitors such as bistrifluron, buprofezin, chlorfluazuron, cyromazine, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, penfluron, teflubenzuron and triflumuron; juvénile hormone mimics, such as epofenonane, fenoxycarb, hydroprene, kinoprene, methoprene, pyriproxyfen and triprene; juvénile hormones such as juvénile hormone I, juvénile hormone II and juvénile hormone III; moulting hormone agonists, such as chromafenozide, halofenozide, methoxyfenozide and tebufenozide; moulting hormones such as σ-ecdysone and ecdysterone; moulting inhibitors, such as diofenolan; precocenes, such as precocene I, precocene II and precocene III; unclassified insect growth regulators, such as dicyclanil; nereistoxin analogue insecticides, such as bensultap, cartap, thiocyclam and thiosultap; nicotinoid insecticides, such as flonicamid; nitroguanidine insecticides, such as clothianidin, dinotefuran, imidacloprid and thiamethoxam; aminofuranone neonicotinoids such as BYI-02960; semisynthetic fermentation products such as cypropen; nitromethylene insecticides, such as nitenpyram and nithiazine; pyridylmethylamine insecticides, such as acetamiprid, imidacloprid, nitenpyram and thiacloprid; organochlorine insecticides, such as bromo-DDT, camphechlor, DDT, pp'-DDT, ethyl-DDD, HCH, gamma-HCH, lindane, methoxychlor, pentachlorophenol and TDE; cyclodiene insecticides such as aldrin, bromocyclen, chlorbicyclen, chlordane, chlordecone, dieldrin, dilor, endosulfan, endrin, HEOD, heptachlor, HHDN, isobenzan, isodrin, kelevan and mirex; organophosphate insecticides, such as bromfenvinfos, chlorfenvinphos, crotoxyphos, dichlorvos, dicrotophos, dimethylvinphos,

-7fospirate, heptenophos, methocrotophos, mevînphos, monocrotophos, naled, naftalofos, phosphamidon, propaphos, TEPP and tetrachlorvinphos; organothiophosphate insecticides, such as dioxabenzofos, fosmethilan and phenthoate; aliphatic organothiophosphate insecticides, such as acethion, amiton, cadusafos, chlorethoxyfos, chlormephos, demephion, demephion-O, demephion-S, demeton, demeton-O, demeton-S, demeton-methyl, demeton-Omethyl, demeton-S-methyl, demeton-S-methylsulphon, disulfoton, ethion, ethoprophos, IPSP, isothioate, malathion, methacrifos, oxydemeton-methyl, oxydeprofos, oxydisulfoton, phorate, sulfotep, terbufos and thiometon; aliphatic amide organothiophosphate insecticides, such as amîdithion, cyanthoate, dimethoate, ethoate-methyl, formothion, mecarbam, omethoate, prothoate, sophamide and vamidothion; oxime organothiophosphate insecticides, such as chlorphoxim, phoxim and phoxim-methyl; heterocyclic organothiophosphate insecticides, such as azamethiphos, coumaphos, coumithoate, dioxathion, endothion, menazon, morphothion, phosalone, pyraclofos, pyridaphenthion and quinothion; benzothiopyran organothiophosphate insecticides, such as dithicrofos and thicrofos; benzotriazine organothiophosphate insecticides such as azinphos-ethyl and azinphos-methyl; isoindole organothiophosphate insecticides, such as dialifos and phosmet; isoxazole organothiophosphate insecticides, such as isoxathion and zolaprofos; pyrazolopyrimidine organothiophosphate insecticides, such as chlorprazophos and pyrazophos; pyridine organothiophosphate insecticides, such as chlorpyrifos and chlorpyrifosmethyl; pyrimidine organothiophosphate insecticides, such as butathiofos, diazinon, etrimfos, lirimfos, pirimiphos-ethyl, pirimiphos-methyl, primidophos, pyrimitate and tebupirimfos; quinoxaline organothiophosphate insecticides, such as quinalphos and quinalphos-methyl; thiadiazole organothiophosphate insecticides, such as athidathion, lythidathion, methidathion and prothidathion; triazole organothiophosphate insecticides, such as isazofos and triazophos; phenyl organothiophosphate insecticides, such as azothoate, bromophos, bromophos-ethyl, carbophenothion, chlorthiophos, cyanophos, cythioate, dicapthon, dichlofenthion, etaphos, famphur, fenchlorphos, fenitrothion fensulfothion, fenthion, fenthion-ethyl, heterophos, jodfenphos, mesulfenfos, parathion, parathion-methyl, phenkapton, phosnichlor, profenofos, prothiofos, sulprofos, temephos, trichlormetaphos-3 and trifenofos; phosphonate insecticides, such as butonate and trichlorfon; phosphonothioate insecticides, such as mecarphon; phenyl ethylphosphonothioate insecticides, such as fonofos and trichloronat; phenyl phenylphosphonothioate insecticides, such as cyanofenphos, EPN and leptophos; phosphoramidate insecticides such as crufomate, fenamiphos, fosthietan, mephosfolan, phosfolan and pirimetaphos; phosphoramidothioate insecticides such as acephate, isocarbophos, isofenphos, methamidophos and propetamphos; phosphorodiamide insecticides, such as dimefox, mazidox, mipafox and schradan; oxadiazine insecticides, such as indoxacarb;

/VTIWOJOA

-8phthalimide insecticides, such as dialifos, phosmet and tetramethrîn; pyrazole insecticides, such as acetoprole, ethiprole, fipronil, pyrafluprole, pyriprole, tebufenpyrad, tolfenpyrad and vaniliprole; pyrethroid ester insecticides, such as acrinathrin, allethrin, bioallethrin, barthrin, bifenthrin, bioethanomethrin, cyclethrin, cycloprothrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, gamma-cyhalothrin, lambda-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, dimefluthrin, dimethrin, empenthrin, fenfluthrin, fenpirithrin, fenpropathrin, fenvalerate, esfenvalerate, flucythrinate, fluvalinate, tau-fluvalinate, furethrin, imiprothrin, metofluthrin, permethrin, biopermethrin, transpermethrin, phenothrin, prallethrin, profluthrin, pyresmethrin, resmethrin, bioresmethrin, cismethrin, tefluthrin, terallethrin, tetramethrîn, tralomethrin and transfluthrin; pyrethroid ether insecticides, such as etofenprox, flufenprox, halfenprox, protrifenbute and silafluofen; pyrimidinamine insecticides, such as flufenerim and pyrimidifen; pyrrole insecticides, such as chlorfenapyr; tetronic acid insecticides, such as spirodiclofen, spiromesifen and spirotetramat; thiourea insecticides such as diafenthiuron; urea insecticides, such as flucofuron and sulcofuron; and unclassified insecticides, such as AKD-3088, closantel, crotamiton, cyflumetofen, EXD, fenazaflor, fenazaquin, fenoxacrim, fenpyroximate, FKI-1033, flubendiamide, cyazypyr (cyantraniliprole), hydramethylnon, IKI-2002, isoprothiolane, malonoben, metaflumizone, metoxadiazone, nifiuridide, NNI-9850, NN1-0101 (pyrifluquinazon), pymetrozine, pyridaben, pyridalyl, Qcide, rafoxanide, rynaxypyr (chlorantraniliprole), SYJ-159, triarathene, and triazamate, and any combinations thereof.

Some of the fungicides that can be employed beneficially in combination with the formulations of the présent invention include: 2-(thiocyanatomethylthio)-benzothiazole, 2phenylphenol, 8-hydroxyquinoline sulfate, Ampelomyces, quisqualis, azaconazole, azoxystrobin, Bacillus subti/is, benalaxyl, benomyl, benthiavalicarb-isopropyl, benzylaminobenzene-sulfonate (BABS) sait, bicarbonates, biphenyl, bismerthiazol, bitertanol, blasticidin-S, borax, Bordeaux mixture, boscalid, bromuconazole, bupirimate, calcium polysulfide, captafol, captan, carbendazim, carboxin, carpropamid, carvone, chloroneb, chlorothalonil, chlozolinate, Coniothyrium minitans, copper hydroxide, copper octanoate, copper oxychloride, copper sulfate, copper sulfate (tribasic), cuprous oxide, cyazofamid, cyflufenarnid, cymoxanil, cyproconazole, cyprodinil, dazomet, debacarb, diammonium ethylenebis(dithiocarbamate), dichlofluanid, dichlorophen, diclocymet, diclomezine, dichloran, diethofencarb, difenoconazole, difenzoquat ion, diflumetorim, dimethomorph, dimoxystrobin, diniconazole, diniconazole-M, dinobuton, dinocap, diphenylamine, dithianon, dodemorph, dodemorph acetate, dodine, dodine free base, edifenphos, epoxiconazole, ethaboxam, ethoxyquin, etridiazole, famoxadone, fenamidone, fenarimol, fenbuconazole, fenfuram,

-9fenhexamid, fenoxanil, fenpiclonil, fenpropidin, fenpropimorph, fentin, fentin acetate, fentin hydroxide, ferbam, ferimzone, fluazinam, fludioxonil, flumorph, fluopicolide, fluoroimide, fluoxastrobin, fluquinconazole, flusilazole, flusulfamide, flutolanil, flutriafol, folpet, formaldéhyde, fosetyl, fosetyl-aluminîum, fuberidazole, furalaxyl, furametpyr, guazatine, guazatine acétates, GY-81, hexachlorobenzene, hexaconazole, hymexazol, imazalil, imazalil sulfate, imibenconazole, iminoctadine, ïminoctadine triacetate, iminoctadine tris(albesilate), ipconazole, iprobenfos, iprodione, iprovalicarb, isoprothiolane, kasugamycin, kasugamycin hydrochloride hydrate, kresoxim-methyl, mancopper, mancozeb, maneb, mepanipyrim, mepronil, mercuric chloride, mercuric oxide, mercurous chloride, metalaxyl, mefenoxam, metalaxyl-M, metam, metam-ammonium, metam-potassium, metam-sodium, metconazole, methasulfocarb, methyl iodide, methyl isothiocyanate, metiram, metominostrobin, metrafenone, mildiomycin, myclobutanil, nabam, nitrothal-isopropyl, nuarimol, octhilinone, ofurace, oleic acid (fatty acids), orysastrobin, oxadixyl, oxine-copper, oxpoconazole fumarate, oxycarboxin, pefurazoate, penconazole, pencycuron, pentachlorophenol, pentachlorophenyl laurate, penthiopyrad, phenylmercury acetate, phosphonic acid, phthalide, picoxystrobin, polyoxin B, polyoxins, polyoxorim, potassium bicarbonate, potassium hydroxyquinoline sulfate, probenazole, prochloraz, procymldone, propamocarb, propamocarb hydrochloride, propiconazole, propineb, proquinazid, prothioconazole, pyraclostrobin, pyrazophos, pyributicarb, pyrifenox, pyrimethanil, pyroquilon, quinoclamine, quinoxyfen, quintozene, Reynoutria sachalinensis extract, silthiofam, simeconazole, sodium 2-phenylphenoxide, sodium bicarbonate, sodium pentachlorophenoxide, spiroxamine, sulfur, SYP-Z071, taroils, tebuconazole, tecnazene, tetraconazole, thiabendazole, thifluzamide, thiophanate-methyl, thiram, tiadinil, tolclofos-methyl, tolylfluanid, triadimefon, triadimenol, triazoxide, tricyclazole, tridemorph, trifloxystrobin, triflumizole, triforine, triticonazole, validamycin, vinclozolin, zineb, ziram, zoxamide, Candida oleophila, Fusarium oxysporum, Gliocladium spp., Phlebiopsis gigantean, Streptomyces griseoviridis, Trichoderma spp., (RS)— N-(3,5-dichlorophenyl)-2-(methoxymethyl)-succinimide, 1,2-dichloropropane, 1,3-dichloro1,1,3,3-tetrafluoroacetone hydrate, 1-chloro-2,4-dinitronaphthalene, 1-chloro-2-nitropropane, 2(2-heptadecyl-2-imidazolin-1-yl)ethanol, 2,3-dihydro-5-phenyl-1,4-dithi-ine 1,1,4,4-tetraoxide, 2methoxyethylmercury acetate, 2-methoxyethylmercury chloride, 2-methoxyethylmercury silicate, 3-(4-chlorophenyl)-5-methylrhodanine, 4-(2-nitroprop-1 -enyl)phenyl thiocyanateme: ampropylfos, anilazine, azithiram, barium polysulfide, Bayer 32394, benodanil, benquinox, bentaluron, benzamacril; benzamacril-isobutyl, benzamorf, binapacryl, bis(methylmercury) sulfate, bis(tributyltin) oxide, buthiobate, cadmium calcium copper zinc chromate sulfate, carbamorph, CECA, chlobenthiazone, chloraniformethan, chlorfenazole, chlorquinox, climbazole, copper bis(3-phenylsalicylate), copper zinc chromate, cufraneb, cupric hydrazinium

-10sulfate, cuprobam, cyclafuramid, cypendazole, cyprofuram, decafentin, dichlone, dichlozoline, diclobutrazol, dimethirimol, dinocton, dinosulfon, dinoterbon, dîpyrithione, dîtalimfos, dodicin, drazoxolon, EBP, ESBP, etaconazole, etem, ethirim, fenaminosulf, fenapanîl, fenîtropan, fluotrimazole, furcarbanil, furconazole, furcortazole-cis, furmecyclox, furophanate, glyodine, griseofulvin, halacrinate, Hercules 3944, hexylthiofos, ICIA0858, isopamphos, isovaledione, mebenil, mecarbinzid, metazoxolon, methfuroxam, methylmercury dicyandiamide, metsulfovax, milneb, mucochloric anhydride, myclozolin, N-3,5-dichlorophenyl-succinimide, N-3nitrophenylitaconimide, natamycin, N-ethylmercurio-4-toluenesulfonanilide, nickel bis(dimethyldîthiocarbarnate), OCH, phenylmercury dimethyldithiocarbamate, phenylmercury nitrate, phosdiphen, prothiocarb; prothiocarb hydrochloride, pyracarbolîd, pyridinitrîl, pyroxychlor, pyroxyfur, quinacetol; quinacetol sulfate, quinazamid, quinconazole, rabenzazole, salicylanilide, SSF-109, sultropen, tecoram, thiadifluor, thicyofen, thiochlorfenphim, thiophanate, thioquinox, tioxymid, triamiphos, triarimol, triazbutil, trichlamide, urbacid, XRD-563, and zarilamid, and any combinations thereof.

Some of the herbicides that can be employed in conjunction with the formulations of the présent invention include: amide herbicides such as allidochlor, beflubutamid, benzadox, benzipram, bromobutide, cafenstrole, CDEA, chlorthiamid, cyprazole, dimethenamid, dimethenamid-P, diphenamid, epronaz, etnipromid, fentrazamide, flupoxam, fomesafen, halosafen, isocarbamid, îsoxaben, napropamide, naptalam, pethoxamid, propyzamide, quinonamid and tebutam; anilide herbicides such as chloranocryl, cisanilide, clomeprop, cypromid, diflufenican, etobenzanid, fenasulam, flufenacet, flufenican, mefenacet, mefluidide, metamifop, monalide, naproanilide, pentanochlor, picolinafen and propanil; arylalanine herbicides, such as benzoylprop, flamprop and flamprop-M; chloroacetanilide herbicides, such as acetochlor, alachlor, butachlor, butenachlor, delachlor, diethatyl, dimethachlor, metazachlor, metolachlor, S-metolachlor, pretilachlor, propachlor, propisochlor, prynachlor, terbuchlor, thenylchlor and xylachlor; sulfonanilide herbicides, such as benzofluor, perfluidone, pyrimisulfan and profluazol; sulfonamide herbicides, such as asulam, carbasulam, fenasulam and oryzalin; antibiotic herbicides, such as bilanafos; benzoic acid herbicides, such as chloramben, dicamba, 2,3,6-TBA and tricamba; pyrimidinyloxybenzoic acid herbicides, such as bispyribac and pyriminobac; pyrimidinylthiobenzoic acid herbicides, such as pyrithiobac; phthalic acid herbicides, such as chlorthal; picolinic acid herbicides such as aminopyralid, clopyralid and picloram; quinolinecarboxylic acid herbicides, such as quinclorac and quinmerac; arsenical herbicides, such as cacodylic acid, CMA, DSMA, hexaflurate, MAA, ΜΑΜΑ, MSMA, potassium arsenite and sodium arsenite; benzoylcyclohexanedione herbicides, such as mesotrione, sulcotrione, tefuryltrione and tembotrione; benzofuranyl alkylsulfonate herbicides, such as benfuresate and ethofumesate; carbamate herbicides, such as asulam, carboxazole chlorprocarb, dichlormate, fenasulam, karbutilate and terbucarb; carbanilate herbicides, such as barban, BCPC, carbasulam, carbetamide, CEPC, chlorbufam, chlorpropham, CPPC, desmedipham, phenisopham, phenmedipham, phenmedipham-ethyl, propham and swep; cyclohexene oxime herbicides, such as alloxydim, butroxydim, clethodim, cloproxydim, cycloxydim, profoxydim, sethoxydim, tepraloxydim and tralkoxydim; cyclopropylisoxazole herbicides, such as isoxachlortole and isoxaflutole; dicarboximide herbicides, such as benzfendizone, cinidon-ethyl, flumezin, flumiclorac, flumioxazin and flumipropyn; dinitroaniline herbicides, such as benfluralin, butralin, dinitramine, ethalfluralin, fluchloralin, isopropalin, methalpropalin, nitralin, oryzalin, pendimethalin, prodiamine, profluralin and trifluralin; dinitrophenol herbicides, such as dinofenate, dinoprop, dinosam, dinoseb, dinoterb, DNOC, etinofen and medinoterb; diphenyl ether herbicides, such as ethoxyfen; nitrophenyl ether herbicides, such as acifluorfen, aclonifen, bifenox, chlomethoxyfen, chlornitrofen, etnipromid, fluorodifen, fluoroglycofen, fluoronitrofen, fomesafen, furyloxyfen, halosafen, lactofen, nitrofen, nitrofluorfen and oxyfluorfen; dithiocarbamate herbicides, such as dazomet and metam; halogenated aliphatic herbicides, such as alorac, chloropon, dalapon, flupropanate, hexachloroacetone, îodomethane, methyl bromide, monochloroacetic acid, SMA and TCA; imidazolinone herbicides, such as imazamethabenz, imazamox, imazapic, imazapyr, imazaquin and imazethapyr; inorganic herbicides, such as ammonium sulfamate, borax, calcium chlorate, copper sulfate, ferrous sulfate, potassium azide, potassium cyanate, sodium azide, sodium chlorate and sulfuric acid; nitrile herbicides, such as bromobonil, bromoxynil, chloroxynil, dichlobenil, iodobonil, ioxynil and pyraclonil; organophosphorus herbicides, such as amiprofosmethyl, anilofos, bensulide, bilanafos, butamifos, 2,4-DEP, DMPA, EBEP, fosamine, glufosinate, glyphosate and piperophos; phenoxy herbicides, such as bromofenoxim, clomeprop, 2,4-DEB,

2,4-DEP, difenopenten, disul, erbon, etnipromid, fenteracol and trifopsime; phenoxyacetic herbicides, such as 4-CPA, 2,4-D, 3,4-DA, MCPA, MCPA-thioethyl and 2,4,5-T; phenoxybutyric herbicides, such as 4-CPB, 2,4-DB, 3,4-DB, MCPB and 2,4,5-TB; phenoxypropionic herbicides, such as cloprop, 4-CPP, dichlorprop, dichlorprop-P, 3,4-DP, fenoprop, mecoprop and mecoprop-P; aryloxyphenoxypropionic herbicides, such as chlorazifop, clodinafop, clofop, cyhalofop, diclofop, fenoxaprop, fenoxaprop-P, fenthiaprop, fluazifop, fluazifop-P, haloxyfop, haîoxyfop-P, isoxapyrifop, metamifop, propaquizafop, quizalofop, quizalofop-P and trifop; phenylenediamine herbicides, such as dinitramine and prodiamine; pyrazolyl herbicides, such as benzofenap, pyrazolynate, pyrasulfotole, pyrazoxyfen, pyroxasulfone and topramezone; pyrazolylphenyl herbicides, such as fluazolate and pyraflufen; pyridazine herbicides, such as credazine, pyridafol and pyrîdate; pyridazinone herbicides, such as brompyrazon, chloridazon, dimidazon, flufenpyr, metflurazon, norflurazon, oxapyrazon and pydanon; pyridine herbicides such as aminopyralid, cliodinate, clopyralid, dithiopyr, fluroxypyr, haloxydine, picloram, picolinafen, pyriclor, thiazopyr and triclopyr; pyrimidinediamine herbicides, such as iprymidam and tioclorim; quatemary ammonium herbicides, such as cyperquat, diethamquat, difenzoquat, diquat, morfamquat and paraquat; thiocarbamate herbicides, such as butylate, cycloate, diallate, EPTC, esprocarb, ethiolate, isopolinate, methiobencarb, molinate, orbencarb, pebulate, prosulfocarb, pyributicarb, sulfallate, thiobencarb, tiocarbazil, tri-allate and vemolate; thiocarbonate herbicides, such as dimexano, EXD and proxan; thiourea herbicides such as methiuron; triazine herbicides, such as dipropetryn, triaziflam and trihydroxytriazine; chlorotriazine herbicides, such as atrazine, chlorazine, cyanazine, cyprazine, eglinazine, ipazine, mesoprazine, procyazine, proglinazine, propazine, sebuthylazine, simazine, terbuthylazine and trietazine; methoxytriazine herbicides, such as atraton, methometon, prometon, secbumeton, simeton and terbumeton; methylthiotriazine herbicides, such as ametryn, aziprotryne, cyanatryn, desmetryn, dimethametryn, methoprotryne, prometryn, simetryn and terbutryn; triazinone herbicides, such as ametridione, amibuzin, hexazinone, isomethiozin, metamitron and metribuzin; triazole herbicides, such as amitrole, cafenstrole, epronaz and flupoxam; triazolone herbicides, such as amicarbazone, bencarbazone, carfentrazone, flucarbazone, propoxycarbazone, sulfentrazone and thiencarbazone-methyl; triazolopyrimidine herbicides, such as cloransulam, diclosulam, florasulam, flumetsulam, metosulam, penoxsulam and pyroxsulam; uracil herbicides, such as butafenacil, bromacil, flupropacil, isocil, lenacil and terbacil; 3-phenyluracils; urea herbicides, such as benzthiazuron, cumyluron, cycluron, dichloralurea, diflufenzopyr, isonoruron, isouron, methabenzthiazuron, monisouron and noruron; phenylurea herbicides, such as anisuron, buturon, chlorbromuron, chloreturon, chlorotoluron, chloroxuron, daimuron, difenoxuron, dimefuron, diuron, fenuron, fluometuron, fluothiuron, isoproturon, linuron, methiuron, methyldymron, metobenzuron, metobromuron, metoxuron, monolinuron, monuron, neburon, parafluron, phenobenzuron, siduron, tetrafluron and thidiazuron; pyrimidinylsulfonylurea herbicides, such as amidosulfuron, azimsulfuron, bensulfuron, chlorimuron, cyclosulfamuron, ethoxysulfuron, flazasulfuron, flucetosulfuron, flupyrsulfuron, foramsulfuron, halosulfuron, imazosulfuron, mesosulfuron, nicosulfuron, orthosulfamuron, oxasulfuron, primisulfuron, pyrazosulfuron, rimsulfuron, sulfometuron, sulfosulfuron and trifloxysulfuron; triazinylsulfonylurea herbicides, such as chlorsulfuron, cinosulfuron, ethametsulfuron, iodosulfuron, metsulfuron, prosulfuron, thifensulfuron, triasulfuron, tribenuron, triflusulfuron and tritosulfuron; thiadiazolylurea herbicides, such as buthiuron, ethidimuron, tebuthiuron, thiazafluron and thidiazuron; and unclassified herbicides such as acrolein, allyl alcohol, azafenidin, benazolin, bentazone,

-13benzobicyclon, buthidazole, calcium cyanamide, cambendichlor, chlorfenac, chlorfenprop, chlorflurazole, chlorflurenol, cinmethylin, clomazone, CPMF, cresol, ortho-dîchlorobenzene, dimepiperate, endothal, fluoromidine, fluridone, flurochloridone, flurtamone, fluthiacet, indanofan, methazole, methyl isothiocyanate, nipyraclofen, OCH, oxadiargyl, oxadiazon, oxaziclomefone, pentachlorophenol, pentoxazone, phenylmercury acetate, pinoxaden, prosulfalîn, pyribenzoxim, pyriftalid, quinoclamine, rhodethanil, sulglycapin, thîdiazimrn, tridiphane, trimeturon, tripropindan, and tritac.

Other compounds and materials may be added provided they do not substantially interfère with the attractant activity of the composition of the invention. Whether or not an additive substantially interfères with the attractant activity can be determined by standard test formats including those that involve direct comparisons of the efficacy of the formulations of the présent invention without at least one added compound and the composition of the présent invention with at least one additional compound.

EXPERIMENTS AND RESULTS

1. Préparation of Formulation A.

A pregel including about 1.5wt% of Rilanit Plus® was made before assembling the formulation. The pregel was formed by adding Rilanit Plus® powder to a clean vessel with the designed amount of solvent (See Table 1), heating it to about 70°C, and holding it at that température for about 5 minutes. The formulation was completed by adding solvent (i.e., Exxsol D-130, Soybean oil and Aromatic 200ND), pregel, surfactants, and sulfoxaflor into a clean vessel under constant mixing. The mixture was then placed into a medium mill and ground for about 5 minutes using 1 mm glass beads. After mîlling, the formulation was packaged into a glass container for further évaluation.

2. Préparation of Formulation B.

A pregel including about 1.5wt% of Rilanit Plus® was made before assembling the formulation. The pregel was formed by adding Rilanit Plus® powder to a clean vessel with the designed amount of solvent (See Table 1), heating it to about 70°C and holding it at that température for about 5 minutes. The formulation was completed by adding solvent (i.e., Exxsol D-130, Soybean oil and Aromatic 200ND), pregel, surfactants, and sulfoxaflor into a clean vessel under constant mixing. The mixture was then placed into a medium mill and ground for about 5 minutes using 1 mm glass beads. After milling, the formulation was packaged into a glass container for further évaluation.

3. Préparation of Formulation C.

A pregel including about 1.5 wt% of Rïlanit Plus® was made before assembling the formulation. The pregel was formed by adding Rïlanit Plus® powder to a clean vessel with the designed amount of solvent (See Table 1), heating it to about 70°C and holding it at that 5 température for about 5 minutes. The formulation was completed by adding solvent (i.e., Exxsol D-130, Soybean oil and Aromatic 200ND), pregel, surfactants and sulfoxaflor into a clean vessel under constant mixing. The mixture was then placed into a medium mill and ground for about five minutes using 1 mm glass beads, After milling, the formulation was packaged into a glass container for further évaluation.

Table 1. Composition of Various Formulations that include Sulfoxaflor as the active ingrédient.

	A.	B.	C.	D.
Ingrédients	g/100 ml	g/100 ml	g/100 ml	g/100 ml
Sulfoxaflor	24	24	24	24
Rilanit Plus pregel (1.5%)	46	25	50
Exxsol D-130	balance
Agnique BL 4110	9
Eumulgin O 5	1
Soybean oil		balance
Agnique BL 4130		10
Aromatic 200ND			balance
Tensiofix N9824HF			9	4
Atlox 4912			1
Aerosil R974				3.5
Water				3
Methylated soybean oil				balance
Tensiofix N9811HF				12

-15Table 2: Chemical Names and/or Descriptions ofthe Components Identified in Table 1 by Trade Name.

Trade Name	Description - Source
Sulfoxaflor	Sulfoxaflor from Dow AgroSciences LLC
Rilanit Plus	Modified organic amide from Cognis Group, headquartered in Monheim, Germany
Exxsol D-130	Hydrocarbon fluid from ExxonMobil Chemical Co., Baytown, TX
Agnique BL 4110	Proprietary emulsifier blend from Cognis Group, headquartered in Monheim, Germany
Eumulgin 0 5	Ethoxylated Oleyl-Cetyl Alcohol from Cognis Group, headquartered in Monheim, Germany
Soybean oil
Agnique BL 4130	Proprietary emulsifier blend from Cognis Group, headquartered in Monheim, Germany
Aromatic 200ND	Naphthalene depleted heavy aromatic fluid from ExxonMobil Chemical Co., Baytown, TX
Tensiofix N9824HF	Proprietary emulsifier blend from S.A. Ajinomoto OmniChem N.V, headquartered in Mont-St-Guibert, Belgium
Atlox 4912	Nonionic block copolymer from Croda Inc headquartered in Edison, NJ
Aerosil R974	Hydrophobically modified fumed silica from Evonik Degussa GmbH, headquartered in Essen, Germany
Water
Methylated soybean oil
Tensiofix N9811HF	Proprietary emulsifier blend from S.A. Ajinomoto OmniChem N.V, headquartered in Mont-St-Guibert, Belgium

4. Préparation of Formulation D,

The solvent methylated soybean oil was added into a clean vessel, next Aerosil R974 was added to vessel during a period of high shear mixing using a Silverson bench top batch homogenizer. After R974 was fully dispersed, the other ingrédients (listed in Table 1) were added to the mixture in no particular order. The resulting mixture was homogenized for about five minutes to furnish the final formulation.

5. Standard (Std.) Formulation.

The standard formulation used as comparison in this invention was an aqueous suspension concentrate of sulfoxaflor with an active ingrédient concentration of 240 g/L.

6. Treatment of Plants to Détermine the Efficacy of Various Formulations.

Cotton plants were infested with whitefly eggs and plants with uniform infestation were selected for trial. Experimental formulations were diluted to the appropriate concentration in water and spray application was made when eggs hatched to become crawlers using a track sprayer calibrated to deliver 200 Uha. Whitefly control from each treatment was determined by counting number of 4^th instar nymphs (red-eye) using a stéréoscope. Experiments were carried out at two rates of a. i. (800 ppm and 200 ppm) for each formulation treatments with four replicate plants tested for each concentration.

Referring now to Table 3, results from testing these formulation on cotton plants (Table 3) demonstrate improved whitefly control from OD formulations D and A) at both concentrations (800 ppm and 200 ppm) over Std. formulation. Moderato level of control was obtained with Std. at 800 ppm (46%), but excellent control (92%) was obtained with formulation D and very good control was obtained with formulation A (78%).

Table 3. Results of Treating with Various Formulations

#	Treatment Name	%ai	Desired PPm	% Control
1	Std.	22	800	46
2			200	30
3	D.	22	800	92
4			200	48

r. _ . . . * ·ιί^νΐΛ «

5	A	22	800	78
6			200	52
7	Untreated			0

The study was repeated. Referring now to Table 4 in the second study, as in the first study, better whitefiy control was obtained by the addition of blank Oil Dispersed (OD), to Std.

and from OD formulations (B, C, and A) than from treatment with only the Std. formulation. Whereas only 45% control was obtained with Std. at 800 ppm, enhanced whitefiy control was obtained from addition of blank OD to 800 ppm Std. (66-89%) and from OD formulations at 800 ppm (70-72% control). Only marginal whitefiy control was obtained from blank OD treatments. These results clearly indicate enhanced whitefiy control from sulfoxaflor when formulated as an 10 OD over an SC formulation.

Table 4. Results Obtained by Treatîng Plants with Various Formulations.

#	Treatment Name	Estimated PPM of a. i.	Percent Control
1	Std.	800	45
2	Std. plus B (Blank)	800	89
3		200	67
4	Std. plus C (Blank)	800	66
5		200	60
6	Std. plus A (Blank)	800	81
7		200	59
8	B	800	72
9		200	53
10	C	800	71
11		200	51
12	A	800	70
13		200	39

14	B (Blank)		33
15			24
16	C (Blank)		23
17			29
18	A (Blank)		37
19			19
20	Untreated		0

7. Field Trial of Plants Treated to Détermine the Efficacy of Various Formulations.

Using standard foliar application equipment, various formulations of a sulfoxaflor insecticide were applied to plots of broccoli plants that were infested with Thrips tabaci (Thrips). At various intervals after treatment, five leaves were randomly collected from plants in each plot and placed into a solution of alcohol. The alcohol treated leaves were brought into the laboratory and the number of Thrips on each leaf was counted under a dissecting microscope. Each experiment was repeated four times.

The data collected in this study was transformed using Log(X+1) and analyzed using analysis of variance and the Student-Newman-Keuls test to compare the various treatments applied to the plants. Eight days after treatment, plants that were treated with the Standard formulation (Std.) dtd not hâve significant fewer Thrips than plants that were untreated, while plants treated with the formulations showed statistically significant fewer Thrips than the untreated plants.

Referring now to Table 5. Formulation D provided significantly better control of thrips 3 days after its application than dîd the Std. formulation. Formulation D also provided numerically better control 8 and 17 days after its application than did the Std. formulation.

TABLE 5. Results of Treating Broccoli Plants with Different Formulation of sulfoximine Insecticides.

Formulation	Application rate (g/ha)	No. of thrips per 5 leaves at day after application*
Day 3	Day 8	Day 17
Std.	72	77 a	83 ab	95 a

D	72	8 b	23 a	43 a
A	72	50 ab	60 a	68 a
Untreated	—	638 c	357 b	91 a

*Mean followed by the same letter are not significantly different (P=0.05, S-N-K).

While the novel technology has been illustrated and described in detail in the foregoing description, the same is to be considered as illustrative and not restrictive in character, it being 5 understood that only the preferred embodiments hâve been shown and described and that ail changes and modifications that corne within the spirit of the novel technology are desired to be protected. As well, while the novel technology was illustrated using spécifie examples, theoretical arguments, accounts, and illustrations, these illustrations and the accompanying discussion should by no means be interpreted as limitîng the technology.

Claims (20)

1. An insecticidal formulation, comprising:

a sulfoximine insecticide; and a water-immiscible solvent wherein the sulfoximine is dispersed within said non-watermiscible solvent as particles, and the sulfoximine has insecticidal activity,

2. The formulation according to claim 1, wherein the sulfoximine is sulfoxaflor,

3. The formulation according to claim 1, wherein said water-immiscible solvent is selected from the group consisting of: methylated seed oils, light petroleum distillâtes, heavy petroleum distillâtes, seed oil, N-N-dimethyl alkyl amide, and minerai oils.

4. The formulation according to claim 1, wherein said water-immiscible solvent is methylated soybean oil.

5. The formulation according to claim 1, wherein said water-immiscible solvent is soybean oil.

6. The formulation according to claim 1, wherein said water-immiscible solvent is a hydrocarbon oil.

7. The formulation according to claim 1, wherein said water-immiscible solvent is a naphthalene depleted heavy aromatic solvent.

8. The formulation according to claim 3, further comprising an emulsifier.

9. The formulation according to claim 3, further comprising a second insecticide.

10. The formulation according to claim 3, further comprising at least one agriculturally active ingrédient selected from the group consisting of fungicides, miticides, and herbicides.

11. A method of controlling an infestation of insects, comprising the steps of: providing an oil dispersion, wherein said dispersion includes a sulfoximine insecticide particles dispersed within a water-immiscible solvent; and contacting a surface adjacent to an insect with said oil dispersion.

12. The method according to claim 11, wherein the sulfoximine insecticide is sulfoxaflor.

13. The method according to claim 11, wherein said non-water-miscible solvent is selected from the group consisting of: methylated seed oils, light petroleum distillâtes, heavy petroleum distillâtes and minerai oils.

14. The method according to claim 11, wherein said non-water-miscible solvent is methylated soybean oil.

15. The method according to claim 11, wherein said non-water-miscible solvent is soybean oil.

16. The method according to claim 11, wherein said non-water-miscible solvent is a naphthalene depleted heavy aromatic.

17. The method according to claim 11, wherein the non-water-miscible solvent is a lipophilie hydrocarbon.

18. The method according to claim 11, further including an emulsifier.

19. The method according to claim 11, further including at least one agriculturally active ingrédient selected from the group consisting of: a second insecticide, fongicides, miticides and herbicides.

20. An insecticidal formulation, comprising:

about 10% to about 50% by weight a sulfoximine insecticide;

soybean oil, wherein the sulfoximine insecticide is dispersa a modified organic amide. S 1