OA09319A - New derivatives of azetidin-2-one, 1, 3, 4-trisubstituted, intermediates useful for the synthesis of beta-lactams, and their asymmetric synthesis process. - Google Patents
New derivatives of azetidin-2-one, 1, 3, 4-trisubstituted, intermediates useful for the synthesis of beta-lactams, and their asymmetric synthesis process.Info
- Publication number
- OA09319A OA09319A OA59874A OA59874A OA09319A OA 09319 A OA09319 A OA 09319A OA 59874 A OA59874 A OA 59874A OA 59874 A OA59874 A OA 59874A OA 09319 A OA09319 A OA 09319A
- Authority
- OA
- OAPI
- Prior art keywords
- radical
- denotes
- optionally substituted
- compounds
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Compounds of formula I, consisting of the combination of formulae IA and IB: <IMAGE> in which: R1 denotes a hydrogen atom, a halogen atom, an alkyl radical, a trifluoromethyl radical, an alkoxy radical, a phenyl or benzyl radical (which are optionally substituted), a benzyloxy radical, a cyano radical, an alkoxycarbonyl radical, a carboxyl radical or an alkylamino radical, R2, different from R1, denotes a hydrogen atom, a halogen atom, an alkyl radical, a trifluoromethyl radical, an alkoxy radical, a phenyl or benzyl radical (which are optionally substituted), a benzyloxy radical, a cyano radical, an alkoxycarbonyl radical, a carboxyl radical or an alkylamino radical, each R3 denotes an alkyl radical or the two R3s form together and with the atoms of the dithioacetal functional group to which they are attached a 5- to 7-membered ring, R4 denotes an optionally substituted phenyl radical, a naphthyl radical or a furyl radical, each of R5 and R6, which are identical or different, denotes a hydrogen atom, an alkyl radical or an aryl radical (optionally substituted), and each R7 denotes a methyl radical or the two R7s form together and with the carbon atom to which they are attached a cyclohexane nucleus or a cyclopentane nucleus. The compounds of formula IA and IB are intermediates which are useful for the preparation of compounds of formulae XA and XB: Original abstract incomplete.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8913969A FR2653429B1 (en) | 1989-10-25 | 1989-10-25 | NOVEL DERIVATIVES OF AZETIDIN-2-ONE, 1,3,4-TRISUBSTITUES, INTERMEDIATES USEFUL FOR THE SYNTHESIS OF BETA-LACTAMS, AND THEIR ASYMMETRIC SYNTHESIS PROCESS. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA09319A true OA09319A (en) | 1992-09-15 |
Family
ID=9386756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA59874A OA09319A (en) | 1989-10-25 | 1990-10-25 | New derivatives of azetidin-2-one, 1, 3, 4-trisubstituted, intermediates useful for the synthesis of beta-lactams, and their asymmetric synthesis process. |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0425378B1 (en) |
| JP (1) | JPH0725731B2 (en) |
| AT (1) | ATE113058T1 (en) |
| AU (1) | AU635975B2 (en) |
| CA (1) | CA2028458A1 (en) |
| DE (1) | DE69013461T2 (en) |
| DK (1) | DK0425378T3 (en) |
| ES (1) | ES2064692T3 (en) |
| FR (1) | FR2653429B1 (en) |
| IE (1) | IE903554A1 (en) |
| NZ (1) | NZ235529A (en) |
| OA (1) | OA09319A (en) |
| PT (1) | PT95671A (en) |
| ZA (1) | ZA908130B (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4384998A (en) * | 1981-03-30 | 1983-05-24 | Merck & Co., Inc. | Synthesis of thienamycin from D-glucose |
| US4777252A (en) * | 1987-08-13 | 1988-10-11 | E. R. Squibb & Sons, Inc. | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
| EP0308867B1 (en) * | 1987-09-22 | 1995-07-26 | Shionogi Seiyaku Kabushiki Kaisha | Alkenylsilylazetidinone intermediates for carbapenems |
-
1989
- 1989-10-25 FR FR8913969A patent/FR2653429B1/en not_active Expired - Lifetime
-
1990
- 1990-10-01 NZ NZ235529A patent/NZ235529A/en unknown
- 1990-10-04 IE IE355490A patent/IE903554A1/en unknown
- 1990-10-11 ZA ZA908130A patent/ZA908130B/en unknown
- 1990-10-24 PT PT95671A patent/PT95671A/en not_active Application Discontinuation
- 1990-10-24 JP JP2286939A patent/JPH0725731B2/en not_active Expired - Lifetime
- 1990-10-24 AU AU64967/90A patent/AU635975B2/en not_active Ceased
- 1990-10-24 CA CA002028458A patent/CA2028458A1/en not_active Abandoned
- 1990-10-25 OA OA59874A patent/OA09319A/en unknown
- 1990-10-25 ES ES90403003T patent/ES2064692T3/en not_active Expired - Lifetime
- 1990-10-25 DK DK90403003.8T patent/DK0425378T3/en active
- 1990-10-25 DE DE69013461T patent/DE69013461T2/en not_active Expired - Fee Related
- 1990-10-25 EP EP90403003A patent/EP0425378B1/en not_active Expired - Lifetime
- 1990-10-25 AT AT90403003T patent/ATE113058T1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH03151382A (en) | 1991-06-27 |
| CA2028458A1 (en) | 1991-04-26 |
| DE69013461D1 (en) | 1994-11-24 |
| FR2653429A1 (en) | 1991-04-26 |
| NZ235529A (en) | 1992-08-26 |
| DE69013461T2 (en) | 1995-05-18 |
| PT95671A (en) | 1991-09-13 |
| EP0425378A1 (en) | 1991-05-02 |
| AU6496790A (en) | 1991-05-02 |
| ATE113058T1 (en) | 1994-11-15 |
| FR2653429B1 (en) | 1991-12-20 |
| DK0425378T3 (en) | 1995-02-27 |
| AU635975B2 (en) | 1993-04-08 |
| JPH0725731B2 (en) | 1995-03-22 |
| ES2064692T3 (en) | 1995-02-01 |
| EP0425378B1 (en) | 1994-10-19 |
| ZA908130B (en) | 1991-07-31 |
| IE903554A1 (en) | 1991-05-08 |
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