NZ801152B2 - Increased 2'-fl production by goats - Google Patents
Increased 2'-fl production by goatsInfo
- Publication number
- NZ801152B2 NZ801152B2 NZ801152A NZ80115221A NZ801152B2 NZ 801152 B2 NZ801152 B2 NZ 801152B2 NZ 801152 A NZ801152 A NZ 801152A NZ 80115221 A NZ80115221 A NZ 80115221A NZ 801152 B2 NZ801152 B2 NZ 801152B2
- Authority
- NZ
- New Zealand
- Prior art keywords
- milk
- goats
- goat
- producing
- determining whether
- Prior art date
Links
- 241000283707 Capra Species 0.000 title claims abstract 11
- SNFSYLYCDAVZGP-OLAZETNGSA-N 2'-fucosyllactose Chemical compound O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](O[C@@H]2[C@H](OC(O)[C@H](O)[C@H]2O)CO)O[C@H](CO)[C@H](O)[C@@H]1O SNFSYLYCDAVZGP-OLAZETNGSA-N 0.000 claims abstract 10
- SNFSYLYCDAVZGP-UHFFFAOYSA-N UNPD26986 Natural products OC1C(O)C(O)C(C)OC1OC1C(OC2C(OC(O)C(O)C2O)CO)OC(CO)C(O)C1O SNFSYLYCDAVZGP-UHFFFAOYSA-N 0.000 claims abstract 10
- 238000000034 method Methods 0.000 claims abstract 8
- 235000020251 goat milk Nutrition 0.000 claims abstract 5
- 229940062827 2'-fucosyllactose Drugs 0.000 claims abstract 2
- HWHQUWQCBPAQQH-UHFFFAOYSA-N 2-O-alpha-L-Fucosyl-lactose Natural products OC1C(O)C(O)C(C)OC1OC1C(O)C(O)C(CO)OC1OC(C(O)CO)C(O)C(O)C=O HWHQUWQCBPAQQH-UHFFFAOYSA-N 0.000 claims abstract 2
- 235000013336 milk Nutrition 0.000 claims 7
- 210000004080 milk Anatomy 0.000 claims 7
- 239000008267 milk Substances 0.000 claims 7
- 235000021277 colostrum Nutrition 0.000 claims 1
- 210000003022 colostrum Anatomy 0.000 claims 1
- 108700028369 Alleles Proteins 0.000 abstract 1
- 101150010169 FUT2 gene Proteins 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
Abstract
Disclosed is a method of producing goat milk having naturally present 2'-fucosyllactose (2'-FL). The method comprises determining whether a goat is producing 2'-FL, selecting a plurality of goats that produce 2'-FL; and milking the selected goats. Also disclosed is determining whether the goat producing 2'- FL possesses at least one copy of a favourable allele at a SNP and/or has a deletion in the region of the FUT2 gene.
Claims (6)
1. A method of producing goat milk having naturally present 2’ fucosyllactose (2’-FL), comprising: 5 a) determining whether a goat is producing 2’-FL; b) ing a plurality of goats that produce 2’-FL; and c) milking the selected goats separately from goats that do not have
2’-FL naturally t in the milk. 10 2. The method of claim 1 further comprising collecting the milk of the selected goats as bulk milk for further processing, optionally the bulk milk being at least 150L.
3. The method of claim 2 wherein the bulk milk is at least 1000L, at least 15 5000L, or at least 10,000L.
4. The method of claim 2 or 3 wherein the goat milk is mature milk.
5. The method of claim 2 or 3 wherein the goat milk is rum.
6. The method of claim 2 or 3 wherein the goat milk is a combination of mature milk and colostrum. 20052055_1 (GHMatters) P121990.NZ W0 23036 €Z_L# 8L_L# €L_Z# VL_L# €L_L# ZL_L# 6L_Z# 9L_L# ez‘z# SZ_L# VL_Z# ‘ 92_L# LL_Z# ~ os‘z# ‘ 9_L# oz‘z# 82_L# 2'-FL 9‘z# LZ_L# 1 LZ_Z# Goats gz‘z# €_L#
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20386055 | 2020-12-11 | ||
| EP21156671 | 2021-02-11 | ||
| PCT/EP2021/085253 WO2022123036A1 (en) | 2020-12-11 | 2021-12-10 | Increased 2'-fl production by goats |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NZ801152A NZ801152A (en) | 2024-01-26 |
| NZ801152B2 true NZ801152B2 (en) | 2024-04-30 |
Family
ID=
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4857467A (en) | Carbon and energy source markers for transformation of strains of the genes Pichia | |
| NZ801152B2 (en) | Increased 2'-fl production by goats | |
| Rahimpour et al. | Engineering the cellular protein secretory pathway for enhancement of recombinant tissue plasminogen activator expression in Chinese hamster ovary cells: effects of CERT and XBP1s genes | |
| Robinson et al. | Kinetics of recombinant immunoglobulin production by mammalian cells in continuous culture | |
| NZ801152A (en) | Increased 2’-fl production by goats | |
| Hoang et al. | Modulating endoplasmic reticulum-Golgi cargo receptors for improving secretion of carrier-fused heterologous proteins in the filamentous fungus Aspergillus oryzae | |
| Toussaint et al. | Connecting two unrelated DNA sequences with a Mu dimer | |
| JP2012044883A (en) | Method for producing cell with modified characteristic | |
| US6270988B1 (en) | Process for producing recombinant proteins using a gene for tRNA | |
| CN115941914A (en) | Video rendering system based on video frame analysis | |
| Dalgleish | Effect of milk concentration on the nature of curd formed during renneting–a theoretical discussion | |
| Boumaiza et al. | Getting value from the waste: recombinant production of a sweet protein by Lactococcus lactis grown on cheese whey | |
| Oran et al. | Significance of persistent cytogenetic abnormalities on myeloablative allogeneic stem cell transplantation in first complete remission | |
| Swift et al. | The effect of organic nitrogen sources on recombinant glucoamylase production by Aspergillus niger in chemostat culture | |
| Ramírez et al. | Genetic instability of heterozygous, hybrid, natural wine yeasts | |
| Al‐Hedaithy | The yeast species causing fungemia at a university hospital in Riyadh, Saudi Arabia, during a 10‐year period | |
| US10368558B2 (en) | Lactase solution and dairy product using same | |
| EP2638146B1 (en) | Nuclear dna content of cho cell lines as a selection criterion in screening of the best recombinant protein producers | |
| Tatarinova et al. | METHODOLOGY FOR ACCOUNTING EXPENSES OF DAIRY ENTER-PRISES | |
| Luo et al. | Effect of somatic cells composition on proteolysis and quality of Cheddar cheese | |
| CN109189823B (en) | Data mining method based on continuous casting billet defect analysis | |
| US2786762A (en) | Roquefort-type cheese and processes of preparing the same | |
| Punturiero et al. | Genomic approach to manage genetic variability in dairy farms | |
| Turoscy et al. | Location of the genes that control induction of the allantoin-degrading enzymes in Saccharomyces cerevisiae | |
| Mohan | Genetic Association of Casein Genes with Milk Protein and Their Comparative Expression in HF Crossbred Cattle |