NZ767752A - Targeted delivery of tertiary amine-containing drug substances - Google Patents

Targeted delivery of tertiary amine-containing drug substances

Info

Publication number
NZ767752A
NZ767752A NZ767752A NZ76775215A NZ767752A NZ 767752 A NZ767752 A NZ 767752A NZ 767752 A NZ767752 A NZ 767752A NZ 76775215 A NZ76775215 A NZ 76775215A NZ 767752 A NZ767752 A NZ 767752A
Authority
NZ
New Zealand
Prior art keywords
tertiary amine
containing drug
targeted delivery
drug substances
cancer
Prior art date
Application number
NZ767752A
Inventor
Scott Jeffrey
Patrick J Burke
Joseph Z Hamilton
Original Assignee
Seagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seagen Inc filed Critical Seagen Inc
Priority claimed from NZ730552A external-priority patent/NZ730552A/en
Publication of NZ767752A publication Critical patent/NZ767752A/en

Links

Abstract

Compounds and compositions are disclosed in which a quaternized drug unit is linked to a targeting ligand unit from which a tertiary amine-containing drug is released at the targeted site of action. Methods for treating diseases characterized by the targeted abnormal cells, such as cancer or an autoimmune disease using the compounds and compositions of the invention are also disclosed. The ligand drug conjugate (LDC) composition of formula 1 is used in the treatment of cancer or an autoimmune disease in humans or non-human mammals.
NZ767752A 2014-09-11 2015-09-10 Targeted delivery of tertiary amine-containing drug substances NZ767752A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462049206P 2014-09-11 2014-09-11
US201462087218P 2014-12-03 2014-12-03
US201462087755P 2014-12-04 2014-12-04
NZ730552A NZ730552A (en) 2014-09-11 2015-09-10 Targeted delivery of tertiary amine-containing drug substances

Publications (1)

Publication Number Publication Date
NZ767752A true NZ767752A (en) 2023-12-22

Family

ID=89473733

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ767751A NZ767751A (en) 2014-09-11 2015-09-10 Targeted delivery of tertiary amine-containing drug substances
NZ767752A NZ767752A (en) 2014-09-11 2015-09-10 Targeted delivery of tertiary amine-containing drug substances

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NZ767751A NZ767751A (en) 2014-09-11 2015-09-10 Targeted delivery of tertiary amine-containing drug substances

Country Status (1)

Country Link
NZ (2) NZ767751A (en)

Also Published As

Publication number Publication date
NZ767751A (en) 2023-12-22

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Legal Events

Date Code Title Description
ERR Error or correction

Free format text: THE TITLE HAS BEEN CORRECTED TO TITLE: TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES ; FILING DATE: 10 SEP 2020; STATUS: REJECTED; KIND CODE: A1 PUBLICATION DATE: 25 SEP 2020; TITLE: TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES ; FILING DATE: 21 AUG 2023; STATUS: REJECTED; KIND CODE: TITLE: TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES ; FILING DATE: 14 DEC 2023; STATUS: REJECTED; KIND CODE: TITLE: TARGETED DELIVERY OF TERTIARY AMINE-CONTAINING DRUG SUBSTANCES ; FILING DATE: 15 DEC 2023; STATUS: PROPOSED; KIND CODE:

Effective date: 20231215