NZ755117A - Compositions and methods for modulating hbv and ttr expression - Google Patents
Compositions and methods for modulating hbv and ttr expressionInfo
- Publication number
- NZ755117A NZ755117A NZ755117A NZ75511714A NZ755117A NZ 755117 A NZ755117 A NZ 755117A NZ 755117 A NZ755117 A NZ 755117A NZ 75511714 A NZ75511714 A NZ 75511714A NZ 755117 A NZ755117 A NZ 755117A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compositions
- methods
- ttr expression
- modulating hbv
- hbv
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002777 nucleoside Substances 0.000 abstract 1
- 125000003835 nucleoside group Chemical group 0.000 abstract 1
Abstract
Disclosed is a compound comprising a modified oligonucleotide and a conjugate group, wherein the modified oligonucleotide consists of 8 to 80 linked nucleosides and has a nucleobase sequence that is least 85% complementary to SEQ ID NO: 2.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361818442P | 2013-05-01 | 2013-05-01 | |
US201361823826P | 2013-05-15 | 2013-05-15 | |
US201361843887P | 2013-07-08 | 2013-07-08 | |
US201361871673P | 2013-08-29 | 2013-08-29 | |
US201361880790P | 2013-09-20 | 2013-09-20 | |
US201461976991P | 2014-04-08 | 2014-04-08 | |
US201461986867P | 2014-04-30 | 2014-04-30 | |
NZ74252514 | 2014-05-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ755117A true NZ755117A (en) | 2023-07-28 |
Family
ID=87654782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ755117A NZ755117A (en) | 2013-05-01 | 2014-05-01 | Compositions and methods for modulating hbv and ttr expression |
Country Status (1)
Country | Link |
---|---|
NZ (1) | NZ755117A (en) |
-
2014
- 2014-05-01 NZ NZ755117A patent/NZ755117A/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PSEA | Patent sealed | ||
RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 6 YEARS UNTIL 01 MAY 2024 BY PHILLIPS ORMONDE FITZPATRICK Effective date: 20240124 |