NZ754366A - Novel t cell receptors and immune therapy using the same - Google Patents
Novel t cell receptors and immune therapy using the sameInfo
- Publication number
- NZ754366A NZ754366A NZ754366A NZ75436617A NZ754366A NZ 754366 A NZ754366 A NZ 754366A NZ 754366 A NZ754366 A NZ 754366A NZ 75436617 A NZ75436617 A NZ 75436617A NZ 754366 A NZ754366 A NZ 754366A
- Authority
- NZ
- New Zealand
- Prior art keywords
- taa
- antigen recognizing
- recognizing constructs
- novel
- tcr
- Prior art date
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to antigen recognizing constructs against a tumor associated antigen (TAA) derived from the target protein DDB1 and CUL4 associated factor 4-like 2(DCAF4L2). The invention in particular provides novel T cell receptor (TCR) based molecules which are selective and specific for the TAA of the invention. The TCR of the invention, and TAA binding fragments derived therefrom, are of use for the diagnosis, treatment and prevention of TAA expressing cancerous diseases. Further provided are nucleic acids encoding the antigen recognizing constructs of the invention, vectors comprising these nucleic acids, recombinant cells expressing the antigen recognizing constructs and pharmaceutical compositions comprising the compounds of the invention.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662431580P | 2016-12-08 | 2016-12-08 | |
| DE102016123859.7A DE102016123859B3 (en) | 2016-12-08 | 2016-12-08 | New T cell receptors and their use in immunotherapy |
| PCT/EP2017/081893 WO2018104478A1 (en) | 2016-12-08 | 2017-12-07 | Novel t cell receptors and immune therapy using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ754366A true NZ754366A (en) | 2022-02-25 |
Family
ID=67874111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ754366A NZ754366A (en) | 2016-12-08 | 2017-12-07 | Novel t cell receptors and immune therapy using the same |
Country Status (6)
| Country | Link |
|---|---|
| CL (1) | CL2019001537A1 (en) |
| CO (1) | CO2019006926A2 (en) |
| IL (1) | IL267131A (en) |
| MY (1) | MY196025A (en) |
| NZ (1) | NZ754366A (en) |
| PH (1) | PH12019501263A1 (en) |
-
2017
- 2017-12-07 MY MYPI2019003103A patent/MY196025A/en unknown
- 2017-12-07 NZ NZ754366A patent/NZ754366A/en not_active IP Right Cessation
-
2019
- 2019-06-05 CL CL2019001537A patent/CL2019001537A1/en unknown
- 2019-06-05 IL IL267131A patent/IL267131A/en unknown
- 2019-06-06 PH PH12019501263A patent/PH12019501263A1/en unknown
- 2019-06-27 CO CONC2019/0006926A patent/CO2019006926A2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH12019501263A1 (en) | 2020-01-20 |
| MY196025A (en) | 2023-03-07 |
| CL2019001537A1 (en) | 2019-10-11 |
| IL267131A (en) | 2019-08-29 |
| CO2019006926A2 (en) | 2019-09-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| LAPS | Patent lapsed |