NZ752214A - Arsenic compositions - Google Patents

Arsenic compositions

Info

Publication number
NZ752214A
NZ752214A NZ752214A NZ75221417A NZ752214A NZ 752214 A NZ752214 A NZ 752214A NZ 752214 A NZ752214 A NZ 752214A NZ 75221417 A NZ75221417 A NZ 75221417A NZ 752214 A NZ752214 A NZ 752214A
Authority
NZ
New Zealand
Prior art keywords
arsenic trioxide
arsenic
compositions
nahas2o4
realisation
Prior art date
Application number
NZ752214A
Inventor
Malvin Eutick
Original Assignee
Eupharma Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2016904945A external-priority patent/AU2016904945A0/en
Application filed by Eupharma Pty Ltd filed Critical Eupharma Pty Ltd
Publication of NZ752214A publication Critical patent/NZ752214A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/36—Arsenic; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Abstract

The present invention is predicated on the realisation that problems with the poor water solubility of arsenic trioxide and the extreme difficulty in dissolving arsenic trioxide in anything other than a very basic solution, could be overcome by forming a much more soluble diarsenic tetraoxide, including the compound NaHAs2O4, prior to its delivery to a patient. Pharmaceutical compositions with such compounds and their use in the treatment of cancers is disclosed.
NZ752214A 2016-12-01 2017-08-02 Arsenic compositions NZ752214A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2016904945A AU2016904945A0 (en) 2016-12-01 Arsenic compositions
PCT/AU2017/050807 WO2018098519A1 (en) 2016-12-01 2017-08-02 Arsenic compositions

Publications (1)

Publication Number Publication Date
NZ752214A true NZ752214A (en) 2022-11-25

Family

ID=62240940

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ752214A NZ752214A (en) 2016-12-01 2017-08-02 Arsenic compositions

Country Status (20)

Country Link
US (1) US11241453B2 (en)
EP (1) EP3548044B1 (en)
JP (2) JP7080230B2 (en)
KR (1) KR102487884B1 (en)
CN (1) CN109952105A (en)
AU (1) AU2017368444B9 (en)
BR (1) BR112019007498A2 (en)
CA (1) CA3041357A1 (en)
CL (1) CL2019001422A1 (en)
DK (1) DK3548044T3 (en)
ES (1) ES2964979T3 (en)
IL (1) IL265986B (en)
MX (1) MX2019006107A (en)
NZ (1) NZ752214A (en)
PE (1) PE20191544A1 (en)
PL (1) PL3548044T3 (en)
SG (1) SG11201903064SA (en)
TW (1) TWI808060B (en)
WO (1) WO2018098519A1 (en)
ZA (1) ZA201902156B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20190310A1 (en) 2016-08-01 2019-03-01 Veolia Water Solutions And Tech Support PROCESS TO REMOVE SILICA FROM PRODUCED WATER AND OTHER WASTEWATER STREAMS
IL265986B (en) * 2016-12-01 2022-09-01 Eupharma Pty Ltd Pharmaceutical composition comprising an alkali metal and/or an alkaline earth metal diarsenic (iii) tetraoxide and uses thereof
CA3211092A1 (en) * 2021-02-26 2022-09-01 Intas Pharmaceuticals Ltd. Oral pharmaceutical composition of arsenic trioxide
JP2022151442A (en) * 2021-03-26 2022-10-07 均 石井 Agents for treating leukemia

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2080004A (en) * 1933-05-17 1937-05-11 Frederick E Dearborn Double salt of copper arsenite and a copper salt of an unsaturated fatty acid and process of making the same
US3280046A (en) 1963-03-27 1966-10-18 Dow Chemical Co Polyol ether resins and utility
DE69840057D1 (en) 1997-10-15 2008-11-06 Polarx Biopharmaceuticals Inc Pharmaceutical compositions containing arsenic trioxide for the treatment of central nervous system cancer
ES2395515T3 (en) 1997-11-10 2013-02-13 Memorial Sloan Kettering Cancer Center Arsenic trioxide for use in the treatment of leukemia
CN1471925A (en) * 2002-08-02 2004-02-04 丛繁滋 Arsenic contained composition for directly hard tumour medoicine feed, preparation, preparing method thereof
US7521071B2 (en) 2002-10-09 2009-04-21 Versitech Limited Formulation of oral compositions comprising arsenic trioxide and methods of use thereof
EP1721615A1 (en) 2005-05-09 2006-11-15 Komipharm International Co., Ltd. Pharmaceutical compositions comprising sodium or potassium arsenite for the treatment of urogenital cancer and its metastasis
US20090246291A1 (en) 2008-03-27 2009-10-01 Angelika Burger Method and compositions for treatment of cancer
CN102060722B (en) * 2009-05-01 2014-06-11 常州高新技术产业开发区三维工业技术研究所有限公司 Arsenic compound and preparation method and use thereof
EP2359812A1 (en) 2010-01-18 2011-08-24 Cephalon France Oral lyophilised compositions
CN105435228B (en) * 2014-08-14 2020-08-07 中国科学院上海营养与健康研究所 New anti-tumor application of arsenic trioxide and anti-tumor preparation
ES2954081T3 (en) * 2015-01-29 2023-11-20 Eupharma Pty Ltd Compositions containing arsenic for use in treatment methods
ES2899226T3 (en) * 2015-02-01 2022-03-10 Syros Pharmaceuticals Inc Lyophilized compositions with a high specific surface area containing arsenic intended for oral administration in patients
IL265986B (en) 2016-12-01 2022-09-01 Eupharma Pty Ltd Pharmaceutical composition comprising an alkali metal and/or an alkaline earth metal diarsenic (iii) tetraoxide and uses thereof

Also Published As

Publication number Publication date
DK3548044T3 (en) 2023-12-11
IL265986B (en) 2022-09-01
CL2019001422A1 (en) 2019-08-02
WO2018098519A1 (en) 2018-06-07
ZA201902156B (en) 2021-01-27
IL265986A (en) 2019-06-30
JP2020500845A (en) 2020-01-16
PE20191544A1 (en) 2019-10-24
ES2964979T3 (en) 2024-04-10
BR112019007498A2 (en) 2019-07-02
JP2022069485A (en) 2022-05-11
EP3548044A4 (en) 2020-07-22
TW201821087A (en) 2018-06-16
JP7419415B2 (en) 2024-01-22
SG11201903064SA (en) 2019-05-30
US11241453B2 (en) 2022-02-08
KR20190089865A (en) 2019-07-31
CA3041357A1 (en) 2018-06-07
EP3548044B1 (en) 2023-09-20
EP3548044A1 (en) 2019-10-09
MX2019006107A (en) 2019-08-21
CN109952105A (en) 2019-06-28
JP7080230B2 (en) 2022-06-03
AU2017368444A1 (en) 2019-04-18
AU2017368444B2 (en) 2020-04-30
AU2017368444B9 (en) 2020-07-02
KR102487884B1 (en) 2023-01-11
US20200016196A1 (en) 2020-01-16
PL3548044T3 (en) 2024-03-04
TWI808060B (en) 2023-07-11

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Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 02 AUG 2024 BY SPRUSON + FERGUSON PTY LTD

Effective date: 20230703