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Application filed by Translate Bio IncfiledCriticalTranslate Bio Inc
Priority claimed from NZ719345Aexternal-prioritypatent/NZ719345A/en
Publication of NZ745686ApublicationCriticalpatent/NZ745686A/en
Disclosed is a composition comprising (a) at least one mRNA molecule at least a portion of which encodes a functional secreted polypeptide; and (b) a transfer vehicle comprising a lipid nanoparticle. Also disclosed is the use of the said composition for the treatment of a subject having a deficiency in a functional polypeptide.
NZ745686A2011-06-082012-06-08Lipid nanoparticle compositions and methods for mrna delivery
NZ745686A
(en)