NZ742678A - Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains - Google Patents
Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domainsInfo
- Publication number
- NZ742678A NZ742678A NZ742678A NZ74267812A NZ742678A NZ 742678 A NZ742678 A NZ 742678A NZ 742678 A NZ742678 A NZ 742678A NZ 74267812 A NZ74267812 A NZ 74267812A NZ 742678 A NZ742678 A NZ 742678A
- Authority
- NZ
- New Zealand
- Prior art keywords
- single variable
- immunoglobulin single
- predicting
- techniques
- detecting
- Prior art date
Links
Abstract
Disclosed are immunoglobulin single variable domain constructs such as ScFVs, VHHs and nanobodies comprising modifications to the C-terminal region that reduce protein interference, for example auto antibodies. In particular C-terminal extensions of the VTVSS sequence at the C-terminal end and point mutations at selected sites within the C-terminal region when the protein is folded.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ743369A NZ743369A (en) | 2011-06-23 | 2012-06-25 | Techniques for predicting, detecting and reducing a specific protein interference in assays involving immunoglobulin single variable domains |
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161500464P | 2011-06-23 | 2011-06-23 | |
US201161500360P | 2011-06-23 | 2011-06-23 | |
US201161541368P | 2011-09-30 | 2011-09-30 | |
PCT/EP2011/067132 WO2012042026A1 (en) | 2010-09-30 | 2011-09-30 | Biological materials related to c-met |
US13/435,567 US8703135B2 (en) | 2010-09-30 | 2012-03-30 | Biological materials related to c-Met |
PCT/EP2012/061304 WO2012175400A1 (en) | 2011-06-23 | 2012-06-14 | Serum albumin binding proteins |
NZ72891012 | 2012-06-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ742678A true NZ742678A (en) | 2023-02-24 |
Family
ID=85323566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ742678A NZ742678A (en) | 2011-06-23 | 2012-06-25 | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
Country Status (1)
Country | Link |
---|---|
NZ (1) | NZ742678A (en) |
-
2012
- 2012-06-25 NZ NZ742678A patent/NZ742678A/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PSEA | Patent sealed | ||
RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 9 YEARS UNTIL 25 JUN 2025 BY P.L.BERRY + ASSOCIATES LIMITED Effective date: 20230531 |