NZ729725A - Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof - Google Patents

Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof

Info

Publication number
NZ729725A
NZ729725A NZ729725A NZ72972513A NZ729725A NZ 729725 A NZ729725 A NZ 729725A NZ 729725 A NZ729725 A NZ 729725A NZ 72972513 A NZ72972513 A NZ 72972513A NZ 729725 A NZ729725 A NZ 729725A
Authority
NZ
New Zealand
Prior art keywords
activatable antibodies
methods
growth factor
factor receptor
epidermal growth
Prior art date
Application number
NZ729725A
Inventor
Henry Bernard Lowman
Luc Roland Desnoyers
Shouchun Liu
James William West
Jason Gary Sagert
Olga Vasiljeva
Elizabeth-Edna Mary Menendez
Original Assignee
Cytomx Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytomx Therapeutics Inc filed Critical Cytomx Therapeutics Inc
Publication of NZ729725A publication Critical patent/NZ729725A/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these anti- EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
NZ729725A 2012-04-27 2013-04-26 Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof NZ729725A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261639796P 2012-04-27 2012-04-27
US201261662204P 2012-06-20 2012-06-20
US201361749220P 2013-01-04 2013-01-04
US201361749529P 2013-01-07 2013-01-07
US201361763237P 2013-02-11 2013-02-11
NZ70106213 2013-04-26

Publications (1)

Publication Number Publication Date
NZ729725A true NZ729725A (en) 2018-05-25

Family

ID=62200130

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ729725A NZ729725A (en) 2012-04-27 2013-04-26 Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof

Country Status (1)

Country Link
NZ (1) NZ729725A (en)

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Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 26 APR 2020 BY COMPUTER PACKAGES INC

Effective date: 20190402

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 26 APR 2021 BY COMPUTER PACKAGES INC

Effective date: 20200331

LAPS Patent lapsed