NZ728027B2 - Reduction of infections in healthcare settings using photocatalytic compositions - Google Patents

Reduction of infections in healthcare settings using photocatalytic compositions

Info

Publication number
NZ728027B2
NZ728027B2 NZ728027A NZ72802715A NZ728027B2 NZ 728027 B2 NZ728027 B2 NZ 728027B2 NZ 728027 A NZ728027 A NZ 728027A NZ 72802715 A NZ72802715 A NZ 72802715A NZ 728027 B2 NZ728027 B2 NZ 728027B2
Authority
NZ
New Zealand
Prior art keywords
infection
inanimate
infections
facility
ppm
Prior art date
Application number
NZ728027A
Other versions
NZ728027A (en
Inventor
Devron R Averett
Stewart B Averett
Original Assignee
WELL Shield LLC
Filing date
Publication date
Application filed by WELL Shield LLC filed Critical WELL Shield LLC
Priority claimed from PCT/US2015/036877 external-priority patent/WO2015200161A1/en
Publication of NZ728027A publication Critical patent/NZ728027A/en
Publication of NZ728027B2 publication Critical patent/NZ728027B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/088Radiation using a photocatalyst or photosensitiser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20Targets to be treated
    • A61L2202/25Rooms in buildings, passenger compartments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00Disinfection, sterilisation or deodorisation of air
    • A61L9/16Disinfection, sterilisation or deodorisation of air using physical phenomena
    • A61L9/18Radiation
    • A61L9/20Ultraviolet radiation
    • A61L9/205Ultraviolet radiation using a photocatalyst or photosensitiser
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/06Silicon, titanium, zirconium or hafnium; Oxides or hydroxides thereof
    • B01J21/063Titanium; Oxides or hydroxides thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/06Silicon, titanium, zirconium or hafnium; Oxides or hydroxides thereof
    • B01J21/08Silica
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/06Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of zinc, cadmium or mercury
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J35/00Catalysts, in general, characterised by their form or physical properties
    • B01J35/20Catalysts, in general, characterised by their form or physical properties characterised by their non-solid state
    • B01J35/23Catalysts, in general, characterised by their form or physical properties characterised by their non-solid state in a colloidal state
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J35/00Catalysts, in general, characterised by their form or physical properties
    • B01J35/30Catalysts, in general, characterised by their form or physical properties characterised by their physical properties
    • B01J35/39Photocatalytic properties
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J35/00Catalysts, in general, characterised by their form or physical properties
    • B01J35/40Catalysts, in general, characterised by their form or physical properties characterised by dimensions, e.g. grain size
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05DPROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D1/00Processes for applying liquids or other fluent materials
    • B05D1/02Processes for applying liquids or other fluent materials performed by spraying
    • B05D1/04Processes for applying liquids or other fluent materials performed by spraying involving the use of an electrostatic field
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Methods of reducing the incidence of healthcare-associated infections in various healthcare settings are provided. Methods for preventing or reducing the number of infections in a human or animal population are also provided. Such methods involve the application of a photocatalytic composition comprising TiO2 doped with zinc and Si or SiO2 to a surface. The methods as provided herein reduce the presence of various infectious agents that are commonly acquired or transmitted and are present on both animate and inanimate surfaces, including those infectious agents commonly found in healthcare settings. By reducing the presence of such infectious agents, the incidence of various types of infection or disease is thereby reduced.

Claims (14)

Claims:
1. A method of reducing the incidence of healthcare-associated infections in a facility by ation to at least one inanimate surface of the facility structure, or at least one inanimate object therein, or a combination thereof, a atalytic composition which is applied at a rate of from about 46.5 m2 per liter to about 139.3 m2 per liter comprising: (a) 5000 to 10000 ppm of titanium dioxide (TiO2); (b) 50 to 150 ppm of zinc; and, (c) 300 to 1000 ppm of n dioxide (SiO2); wherein the care-associated infection is selected from the group consisting of bone infection, joint infection, bloodstream infection, central nervous system infection, cardiovascular system infection, pneumonia, reproductive tract infection, surgical site infection, gastrointestinal infection, lower respiratory infection, upper respiratory infection, skin or soft tissue ion, bloodstream infection, eye ion, ear infection, nose infection, throat infection, mouth infection, and urinary tract infection; wherein the incidence of healthcare-associated infections is d by at least 20% over a twelve month period after one treatment of the inanimate surfaces of the facility structure, at least one object therein, or a combination thereof.
2. The method of claim 1, wherein the photocatalytic composition is applied by spraying, atomizing, coating, immersion, or dipping.
3. The method of claim 1, wherein the nce of healthcare-associated infections is reduced by at least 30% over a twelve month period after one treatment of the inanimate surfaces of the structure, or at least one object therein, or a ation thereof.
4. The method of claim 1, wherein the step of treating inanimate surfaces of the structure, or at least one inanimate object therein, or a ation thereof, prevents and reduces the presence at least one infectious agent selected from the group consisting of species of Acinetobacter, adenovirus, Bacillus, Burkholderia, Bordetella, Brucella, caliciviruses, herpes including zoster (chickenpox), Clostridium, corona viruses ing SARS, MERS, and PEDV, Enterococcus, Escherichia, Hemophilus, hepatitis viruses A and B, influenza and parainfluenza viruses, Klebsiella, Listeria, ella, measles virus, mumps virus, Mycobacterium, Neisseria, norovirus, Pseudomonas, parvovirus, poliovirus, rhinovirus, respiratory syncyticia virus, rus, rubella, Salmonella, Streptococcus, Staphylococcus, Vibrio, MRSA (methicillin-resistant Staphylococcus aureus, VISA (vancomycin intermediate Staphylococcus aureus), MRE (multiply resistant enterococci), and VRE (vancomycin-resistant enterococci)).
5. The method of claim 1, wherein the at least one inanimate surface includes walls, fixtures, floors, and ceilings of hallways, offices, bathrooms, elevators, stairwells, kitchens/cafeterias, common areas, nurses’ stations, and doctors’ stations.
6. The method of claim 1, wherein the at least one inanimate object is selected from the group consisting of curtains, call buttons, computers, monitors, wall computer kiosks, blood pressure cuffs, hairs, lifts, carts, and beds.
7. The method of claim 1, wherein the zinc and/or silicon e ses the absorbance of light of the photocatalytic composition across the range of about 200 nm to about 500 nm.
8. The method of claim 1, wherein the absorbance of light of wavelengths longer than 450 nm is less than 50% the absorbance of light of ngths shorter than 350 nm.
9. The method of claim 1, wherein the titanium dioxide rticles have an average particle size of from about 2 nm to about 20 nm.
10. The method of claim 1, the photocatalytic composition having a ratio of titanium dioxide to silicon dioxide of from about 3 to about 20.
11. The method of claim 1, the photocatalytic composition having a ratio of titanium dioxide to zinc from about 5 to about 150 and a ratio of titanium dioxide to silicon dioxide from about 1 to about 500.
12. A method of preventing or reducing the number of infections in a human or animal population by application to at least one inanimate surface of a structure occupied by the population, or at least one inanimate object present therein, or a combination f, a atalytic composition comprising: (a) 5000 to 10000 ppm of titanium dioxide (TiO2); (b) 50 to 150 ppm of zinc; and, (c) 300 to 1000 ppm of silicon e (SiO2); wherein the ure occupied by the population is selected from the group consisting of an ltural facility, food-processing facility, catering facility, restaurants, hotel, motel, and childcare facility; wherein the incidence of infections is reduced by at least 20% over a twelve month period after one treatment of the inanimate surfaces of the structure, at least one object therein, or a combination f.
13. The method of claim 12, n the nce of infections is reduced by at least 30% over a twelve month period after one treatment of the ate surfaces of the structure, or at least one object therein, or a combination thereof.
14. The method of claim 12, wherein the step of treating inanimate surfaces of the structure, or at least one object therein, or a combination thereof, prevents and reduces the presence at least one ious agent selected from the group consisting of species of Acinetobacter, adenovirus, Bacillus, Burkholderia, Bordetella, Brucella, caliciviruses, herpes ing zoster (chickenpox), Clostridium, corona s including SARS, MERS, and PEDV, Enterococcus, Escherichia, Hemophilus, hepatitis viruses A and B, influenza and parainfluenza viruses, Klebsiella, Listeria, Legionella, measles virus, mumps virus, Mycobacterium, ria, rus, Pseudomonas, parvovirus, poliovirus, rhinovirus, respiratory syncyticia virus, rotavirus, rubella, Salmonella, Streptococcus, Staphylococcus, Vibrio, MRSA (methicillin-resistant Staphylococcus aureus, VISA (vancomycin intermediate Staphylococcus aureus), MRE (multiply resistant enterococci), and VRE (vancomycin-resistant enterococci)). Well Shield LLC By the Attorneys for the Applicant SPRUSON & FERGUSON "0-- lrradiance, W.m-2.nm-1 —Undoped TIOZ —'TIOZ, low Zn — 'TIOZ, low Zn, Si02 “' TIOZ, high Zn, Si02 Wavelength, nm ————-————— W —+— No nanocoating Absorbance — - -Ti02, low Zn “5‘ - ~ - Ti02, low Zn, FIG. 2
NZ728027A 2015-06-22 Reduction of infections in healthcare settings using photocatalytic compositions NZ728027B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462015596P 2014-06-23 2014-06-23
PCT/US2015/036877 WO2015200161A1 (en) 2014-06-23 2015-06-22 Reduction of infections in healthcare settings using photocatalytic compositions

Publications (2)

Publication Number Publication Date
NZ728027A NZ728027A (en) 2023-12-22
NZ728027B2 true NZ728027B2 (en) 2024-03-26

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