NZ722167A - Binding molecules targeting pathogens - Google Patents
Binding molecules targeting pathogensInfo
- Publication number
- NZ722167A NZ722167A NZ722167A NZ72216713A NZ722167A NZ 722167 A NZ722167 A NZ 722167A NZ 722167 A NZ722167 A NZ 722167A NZ 72216713 A NZ72216713 A NZ 72216713A NZ 722167 A NZ722167 A NZ 722167A
- Authority
- NZ
- New Zealand
- Prior art keywords
- binding domains
- mhc
- context
- infected cells
- chain
- Prior art date
Links
Landscapes
- Peptides Or Proteins (AREA)
Abstract
The present invention discloses that targeting infected cells for killing those infected cells can be achieved by providing a proteinaceous molecule comprising a single polypeptide chain comprising at least two specific binding domains separated by at least one linker further comprising an Fc monomer separated from said at least two specific binding domains by at least one linker, wherein said binding domains are Vh domains which specifically recognize a hepatitis C virus derived peptide in the context of MHC-1. More generally, the present invention relates to proteinaceous molecules comprising multiple recombinant antibody-fragments assembled at the DNA level into a single chain, which specifically bind hepatitis C virus derived peptide in the context of MHC-1. In addition, the invention relates to methods of diagnosing and treatment of infectious disease using these recombinant single-chain polypeptides.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261664475P | 2012-06-26 | 2012-06-26 | |
US201261667859P | 2012-07-03 | 2012-07-03 | |
NZ70331613 | 2013-06-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ722167A true NZ722167A (en) | 2019-12-20 |
Family
ID=68847887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ722167A NZ722167A (en) | 2012-06-26 | 2013-06-26 | Binding molecules targeting pathogens |
Country Status (1)
Country | Link |
---|---|
NZ (1) | NZ722167A (en) |
-
2013
- 2013-06-26 NZ NZ722167A patent/NZ722167A/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PSEA | Patent sealed | ||
RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 26 JUN 2021 BY IPAN GMBH Effective date: 20200608 |
|
LAPS | Patent lapsed |