NZ713087B2 - Lutein composition suitable for infant food formulations - Google Patents
Lutein composition suitable for infant food formulations Download PDFInfo
- Publication number
- NZ713087B2 NZ713087B2 NZ713087A NZ71308714A NZ713087B2 NZ 713087 B2 NZ713087 B2 NZ 713087B2 NZ 713087 A NZ713087 A NZ 713087A NZ 71308714 A NZ71308714 A NZ 71308714A NZ 713087 B2 NZ713087 B2 NZ 713087B2
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- New Zealand
- Prior art keywords
- composition
- weight
- composition according
- lutein
- total weight
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 119
- 238000009472 formulation Methods 0.000 title claims abstract description 43
- 235000008452 baby food Nutrition 0.000 title claims abstract description 31
- 235000012680 lutein Nutrition 0.000 title claims abstract description 31
- 229960005375 lutein Drugs 0.000 title claims abstract description 31
- 239000001656 lutein Substances 0.000 title claims abstract description 31
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 title claims abstract description 31
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 title claims abstract description 31
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 title claims abstract description 31
- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 title claims abstract description 29
- 239000000416 hydrocolloid Substances 0.000 claims abstract description 19
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- 239000004615 ingredient Substances 0.000 claims description 14
- 239000012752 auxiliary agent Substances 0.000 claims description 13
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- 150000004676 glycans Chemical class 0.000 claims description 11
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- 239000005017 polysaccharide Substances 0.000 claims description 11
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 10
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- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 4
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- 125000002947 alkylene group Chemical group 0.000 claims description 4
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- 239000000975 dye Substances 0.000 claims description 2
- 235000019285 ethoxyquin Nutrition 0.000 claims description 2
- DECIPOUIJURFOJ-UHFFFAOYSA-N ethoxyquin Chemical compound N1C(C)(C)C=C(C)C2=CC(OCC)=CC=C21 DECIPOUIJURFOJ-UHFFFAOYSA-N 0.000 claims description 2
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- FUWLWBDNQPTINE-UHFFFAOYSA-N 3-tert-butyl-1h-quinolin-2-one Chemical compound C1=CC=C2NC(=O)C(C(C)(C)C)=CC2=C1 FUWLWBDNQPTINE-UHFFFAOYSA-N 0.000 claims 1
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- 239000000843 powder Substances 0.000 description 15
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 4
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 4
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- 210000004080 milk Anatomy 0.000 description 4
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- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
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- RBWSWDPRDBEWCR-RKJRWTFHSA-N sodium;(2r)-2-[(2r)-3,4-dihydroxy-5-oxo-2h-furan-2-yl]-2-hydroxyethanolate Chemical compound [Na+].[O-]C[C@@H](O)[C@H]1OC(=O)C(O)=C1O RBWSWDPRDBEWCR-RKJRWTFHSA-N 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000001334 starch sodium octenyl succinate Substances 0.000 description 1
- 235000013826 starch sodium octenyl succinate Nutrition 0.000 description 1
- RINCXYDBBGOEEQ-UHFFFAOYSA-N succinic anhydride Chemical class O=C1CCC(=O)O1 RINCXYDBBGOEEQ-UHFFFAOYSA-N 0.000 description 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/40—Shaping or working of foodstuffs characterised by the products free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
Abstract
The present invention is related to a powderous composition which comprises lutein and a hydrocolloid and which is used in infant food formulations or premixes for infant food formulations.
Description
LUTEIN COMPOSITION SUITABLE FOR INFANT FOOD FORMULATIONS
The present invention is related to a powderous composition which comprises lutein and
which is used in infant food formulations or premixes for infant food formulations.
Lutein which has the following formula
is obtained usually from plants or eggs.
It can also be synthesized chemically.
Due to the C-C double bonds lutein can have various stereochemical isomers (E/Z forms).
In the context of the present invention the different isomers do not have an essential
effect. The term “lutein” always covers all stereochemical isomers.
It was found that lutein plays a vital role in eye health. The hypothesis for the natural
concentration is that lutein helps keep the eyes safe from oxidative stress and the high-
energy photons of blue light. Various research studies have shown that a direct
relationship exists between lutein intake and pigmentation in the eye.
For that reason lutein is also an important ingredient in the diet for infants (Age 0 – 6).
Therefore, the goal of the present invention was to provide a composition which
comprises lutein and which has excellent properties as such as well as allows to produce
a (infant food) formulation comprising such a composition, which has also excellent
properties.
It was found that a powderous composition comprising particles having
(a) an inner phase, which comprises lutein, and
(b) a matrix, which comprises at least one hydrocolloid,
characterized in that
(i) the inner phase has an average size D [3,2] of less than 30μm, and
(ii) the particle has an average size D [3,2] of 10 – 150μm, and
wherein the inner phase is always smaller than the particle,
does show improved properties.
All the sizes of the inner phase D [3,2] as well as of the particles D [3,2] in the context of
the present patent application were determined by using a Mastersizer 2000. The particle
size of the inner phase was determined after redispersing the powderous composition in
water, whereas the powderous particles of the composition were determined as such.
The composition according to the present invention is used in infant food formulations or
in premixes (which are then used to produce infant food formulations).
The premix is usually in a dry form. The premix is usually produced by mixing the
composition according to the present invention with other suitable ingredients, which are
useful and/or essential in an infant formulation and/or premix (or which are useful and/or
essential for the production of an infant formulation and/or premix).
The infant formulation in the context of the present invention is usually a dry formulation,
which is then dissolved either in water or in milk.
Dry means that the water content is less than 5 weight-% (wt-%), based on the total
weight of the composition, premix or formulation.
The advantages of the composition according to the present invention are:
• the composition is storage stable
• no colored (red) spots in the infant food formulation
• no bleeding when the composition is blended to premix and/or an infant food
formulation
• no color formation, when the infant food formulation is dissolved in water (or milk).
Preferably the inner phase has an average size D [3,2] of 0.1μm to 30μm.
Preferably the inner phase has an average size D [3,2] of 0.2μm to 20μm.
Hydrocolloids are hydrophilic polymers, of vegetable, animal, microbial or synthetic origin,
that generally contain many hydroxyl groups and may be polyelectrolytes.
A hydrocolloid is defined as a colloid system wherein the colloid particles are hydrophilic
polymers dispersed in water. A hydrocolloid has colloid particles spread throughout water,
and depending on the quantity of water available that can take place in different states,
e.g., gel or sol (liquid). Hydrocolloids can be either irreversible (single-state) or reversible.
The hydrocolloids are preferably chosen from the group consisting of modified
polysaccharides, maltodextrin, glucose syrup and gums.
The term “modified polysaccharide” as used in the present specification and claims refers
to a polysaccharide which has been modified by known methods (chemically or
physically, including enzymatic or thermal reactions) to be a good protective hydrocolloid
for the stabilization of lipophilic surfaces in a fine dispersion in the aqueous medium.
Accordingly, the modified polysaccharide has been modified to have a chemical structure
which provides it with a hydrophilic (affinity to water) portion and a lipophilic (affinity to
dispersed phase) portion. This enables it to dissolve in the dispersed lipophilic phase and
in the continuous water phase. Preferably the modified polysaccharide has a long
hydrocarbon chain as part of its structure (preferably C ).
-18
Modified polysaccharides are well known materials which are available commercially, or
may be prepared by a skilled person using conventional methods. A preferred modified
polysaccharide is modified starch. Modified starches are made from starches substituted
by known chemical methods with hydrophobic moieties. For example starch may be
treated with cyclic dicarboxylic acid anhydrides such as succinic anhydrides, substituted
with a hydrocarbon chain (see Modified Starches: Properties and Uses, ed.
O.B.Wurzburg, CRC Press, Inc., Boca Raton, Florida (1991)). A particularly preferred
modified starch of this invention has the following structure (I)
wherein St is a starch, R is an alkylene group and R’ is a hydrophobic group.
Preferably the alkylene group is a lower alkylene group, such as dimethylene or
trimethylene. R’ may be an alkyl or alkenyl group, preferably C to C . A preferred
18
compound of Formula I is starch sodium octenyl succinate. It is available commercially
from, among other sources, Ingredion Inc., as Capsul® and Hicap®. Making this
compound, and compounds of Formula I in general, is known in the art (see Modified
Starches: Properties and Uses, ed. O.B.Wurzburg, CRC Press, Inc., Boca Raton, Florida
(1991)).
Glucose syrup is a food syrup, made from the hydrolysis of starch.
A preferred gum in the context of the present invention is gum Arabic (= gum acacia).
The powderous composition according to the present invention comprises
(a) 0.01 – 30 wt-%, based on the total weight of the composition, of lutein, and
(b) 70 – 99.99 wt-%, based on the total weight of the composition, of at least one
hydrocolloid, and
(c) optionally up to 25 wt-%, based on the total weight of the composition, of at least
one auxiliary agent.
It is clear that all the percentages always add up to 100.
A preferred powderous composition according to the present invention comprises
(a) 0.1 – 15 wt-% based on the total weight of the composition, of lutein and
(b) 70 – 90 wt-%, based on the total weight of the composition, of at least one
hydrocolloid and
(c) 15 – 25 wt-%, based on the total weight of the composition, of at least one
auxiliary agent.
A preferred powderous composition according to the present invention comprises
(a) 0.2 – 10 wt-% based on the total weight of the composition, of lutein and
(b) 75 – 90 wt-%, based on the total weight of the composition, of at least one
hydrocolloid and
(c) 15 – 25 wt-%, based on the total weight of the composition, of at least one
auxiliary agent.
These powderous compositions are dry but they could contain some water (less than 5
wt-%, based on the total weight of the composition, usually less than 3 wt-%).
The auxiliary agents can be any commonly known excipients, which are
• useful for the composition and/or the premix and/or the infant food formulation
and/or
• useful for the production of the composition and/or of the premix and/or of the
infant food formulation.
Such auxiliary agents are for example antioxidants (such as ascorbic acid or salts thereof,
tocopherols (synthetic or natural); butylated hydroxytoluene (BHT); butylat-ed
hydroxyanisole (BHA); propyl gallate; tert. butyl hydroxyquinoline and/or ascorbic acid
esters of a fatty acid); ethoxyquin, plasticisers, stabilisers, humectants (such as glycerol,
sorbitol, polyethylene glycol), dyes, fragrances, fillers and buffers.
Examples are i.e. sugar (saccharides), sodium ascorbate.
The hydrocolloids are preferably chosen from the group consisting of modified
polysaccharides, maltodextrin, glucose syrup and gums, and especially OSA-starch,
maltodextrin and glycose syrup.
The composition according to the present invention is produced by using methods known
from the prior art.
Usually the composition according to the present invention is produced by:
first preparing the water phase which comprises
a) the hydrocolloid or a mixture of hydrocolloids, and
b) optionally at least one auxiliary agent, such as sugar and/or sodium ascorbate,
c) water
by mixing the ingredients (in any sequence) into the water (usually under stirring) and at
ambient temperature.
Afterwards this phase is heated up (to a temperature of between 40 and 90°C).
Then the lutein is added (still at elevated temperature) under vigorous dispersing, which is
optionally followed by a homogenizing process.
Finally the suspension is dried by a method commonly used, such as spray drying.
The powderous compositions according to the present invention are used in infant food
formulations and/or in premixes for infant food formulations.
By the term infant food formulations in the context of the present invention, dry
formulations are meant (especially baby milk formulations), which are then dissolved in a
suitable solvent (usually water or milk, preferably water) and the dissolved form (warm or
cold) is then consumed by the infant.
The infant food formulation can be in any dry form, such powder, granules as well as
tablets.
A preferred infant food formulation is a dry baby milk formulation (powder, granule as or
tablets) wherein the powderous composition according the present invention is
incorporated (lutein fortified baby milk formulation).
Therefore the powderous composition according to the present invention can added as
such to all other ingredients to produce an infant food formulation; or the powderous
composition according to the present invention can be mixed with other ingredients for an
infant food formulation, which is called a premix. This premix is then used to produce an
infant food formulation.
Therefore a further embodiment of the present invention is a process of production of a
dry premix and/or a dry infant food formulation comprising at least one powderous
composition as described above.
The amount of the powderous composition according to the present invention in such a
premix and/or infant food formulation can vary.
The concentration of lutein is usually not more than 0.25 ppm in the liquid infant food
formulation (dry infant food formulation dissolved in milk or preferably in water).
Therefore a further embodiment of the present invention is a dry premix and/or a dry
infant food formulation comprising at least one powderous composition as described
above.
The following examples serve to illustrate the invention. The percentages are expressed
in weight percentages and the temperatures are degrees Celsius, if not otherwise defined.
Examples
Example 1
408.5 g Maltodextrin and 432.2. g HiCap IMF and 210.7g Glucidex 28 E were added to
600 g distilled water. The mixture was stirred and after a few minutes the mixture was
heated to about 60°C. After 20 minutes 10.8 g sodiu m ascorbate was added under
stirring. 10 minutes later 9.6 g lutein was added and the mixture was vigorously
dispersed.
Afterwards the suspension was spray dried.
The following table shows the amounts of the various ingredients after spray drying:
Ingredients Amount [wt-%]
Lutein 1.2
HiCap IMF 40.2
Maltodextrin 38.0
Glucidex 28 E 19.6
Na-Ascorbate 1.0
The average size of the inner phase D[3,2] was 3.19 μm and the average particles size
was 45.92 μm.
Example 2
The same process as in Example 1 was repeated but instead of Glucidex 28 E sugar was
used.
The following table shows the amounts of the various ingredients after spray drying:
Ingredients Amount [wt-%]
Lutein 1.2
HiCap IMF 40.2
Maltodextrin 38.0
Sugar 19.6
Na-Ascorbate 1.0
The average size of the inner phase D[3,2] was 3.02 μm and the average particles size
was 81.82 μm.
Both compositions did not bleed when added to a premix or a infant food formulation.
Furthermore, no color formation was observed when the infant food formulation (baby
milk powder) comprising one of these compositions were dissolved in water.
Example 3: Baby milk powder comprising composition of Example 1
The composition of Example 1 was used adding to a baby milk powder formulation. 0.83 g
of the powderous composition of Example 1 were incorporating (by mixing).
The following table shows the list of ingredients of the lutein fortified baby milk powder:
Ingredients unit Content per 100g Content per 100ml serving
powder
Protein g 9.20 1.4
Carbohydrates g 53.2 8.1
Fat g 23 3.5
Sodium g 0.13 0.02
Potassium mg 493 75
Calcium mg 348 53
Phosphorus mg 197 30
Chloride mg 276 42
Magnesium mg 32.2 4.9
Iron mg 4.60 0.7
Zinc μg 3.3 0.5
Copper μg 263 40
Iodine μg 65 9.9
Manganese μg 46 7
Selenium μg 9.85 1.5
Fluorid μg 38.8 5.9
Vitamin C mg 67.7 10.3
Vitamin A μg 460 70
Vitamin D μg 7.88 1.2
Vitamin E μg 4.6 0.7
Vitamin B1 μg 394 60
Vitamin B2 μg 834 127
Vitamin B6 μg 263 40
Vitamin B12 μg 1 0.15
Folic acid μg 67.7 10.3
Pantotenic acid μg 3258 496
Vitamin K μg 32.2 4.9
Biotin μg 10.51 1.6
Niacin μg 2621 399
Choline mg 99.2 15.1
Inositol mg 32.2 4.9
Lutein μg 1000 152
This lutein fortified baby milk powder showed excellent storage stability. No bleeding was
observed during and after the addition of the composition of Example 1. No colored (red)
spots have been seen in the fortified baby milk powder. Furthermore the baby milk
powder shows excellent dissolving properties in water (dissolves fast) and no color
change of the dissolved baby milk formulation.
Example 4: Baby milk powder comprising composition of Example 1
For this baby milk formulation a lower concentration of the composition of Example 1 was
added (all the other ingredients are the same in the same concentration)
Ingredients unit Content per 100g Content per 100ml serving
powder
Protein g 9.20 1.4
Carbohydrates g 53.2 8.1
Fat g 23 3.5
Sodium g 0.13 0.02
Potassium mg 493 75
Calcium mg 348 53
Phosphorus mg 197 30
Chloride mg 276 42
Magnesium mg 32.2 4.9
Iron mg 4.60 0.7
Zinc μg 3.3 0.5
Copper μg 263 40
Iodine μg 65 9.9
Manganese μg 46 7
Selenium μg 9.85 1.5
Fluorid μg 38.8 5.9
Vitamin C mg 67.7 10.3
Vitamin A μg 460 70
Vitamin D μg 7.88 1.2
Vitamin E μg 4.6 0.7
Vitamin B1 μg 394 60
Vitamin B2 μg 834 127
Vitamin B6 μg 263 40
Vitamin B12 μg 1 0.15
Folic acid μg 67.7 10.3
Pantotenic acid μg 3258 496
Vitamin K μg 32.2 4.9
Biotin μg 10.51 1.6
Niacin μg 2621 399
Choline mg 99.2 15.1
Inositol mg 32.2 4.9
Lutein μg 164 25
Also this lutein fortified baby milk powder showed excellent storage stability. No bleeding
was observed during and after the addition of the composition of Example 1. No colored
(red) spots have been seen in the fortified baby milk powder. Furthermore the baby milk
powder shows excellent dissolving properties in water (dissolves fast) and no color
change of the dissolved baby milk formulation.
Claims (13)
1. Powderous composition comprising particles having (a) an inner phase, which comprises 0.01 – 30 weight-%, based on the total 5 weight of the composition, of lutein, (b) a matrix, which comprises 70 – 99.99 weight-%, based on the total weight of the composition, of at least one hydrocolloid, and (c) optionally up to 25 weight-%, based on the total weight of the composition, of at least one auxiliary agent, 10 characterized in that (i) the inner phase has an average size D [3,2] of 0.1μm to 30μm, and (ii) the particle has an average size D [3,2] of 10 μm – 150 μm, and wherein the inner phase is always smaller than the particle. 15
2. Composition according to claim 1, wherein the inner phase has an average size D [3,2] of 0.2 μm to 20 μm.
3. Composition according to any one of the preceding claims, wherein the hydrocolloid is chosen from the group consisting of polysaccharides, modified polysaccharides, 20 maltodextrin, glucose syrup and gums.
4. Composition according to any one of the preceding claims, wherein the modified polysaccharide is a modified starch of structure (I) wherein St is a starch, R is an alkylene group and R’ is a hydrophobic group.
5. Composition according to any one of the preceding claims, wherein the gum is gum Arabic.
6. Composition according to any one of the preceding claims 1 – 5, comprising (a) 0.1 – 15 weight-% based on the total weight of the composition, of lutein and (b) 70 – 90 weight-%, based on the total weight of the composition, of at least one hydrocolloid and (c) 15 – 25 weight-%, based on the total weight of the composition, of at least one 5 auxiliary agent.
7. Composition according to any one of the preceding claims 1 – 5, comprising (a) 0.2 – 10 weight-% based on the total weight of the composition, of lutein and (b) 75 – 90 weight-%, based on the total weight of the composition, of at least one 10 hydrocolloid and (c) 15 – 24.8 weight-%, based on the total weight of the composition, of at least one auxiliary agent.
8. Composition according to claim 6 or claim 7, wherein the auxiliary agent is chosen 15 from the group consisting of antioxidants; ethoxyquin, plasticisers, stabilisers, humectants, dyes, fragrances, fillers and buffers.
9. Composition according to claim 8, wherein when the auxiliary agent is an antioxidant, said antioxidant is chosen from the group consisting of ascorbic acid or salts 20 thereof, natural and synthetic tocopherols, butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA), propyl gallate, tert-butyl hydroxyquinoline and ascorbic acid esters of a fatty acid.
10. Composition according to claim 8, wherein when the auxiliary agent is a humectant, 25 said humectant is chosen from the group consisting of glycerol, sorbitol and polyethylene glycol.
11. Process of production of a dry premix and/or a dry infant food formulation comprising a step of mixing at least one powderous composition according to any one of 30 claims 1 – 10 with other suitable ingredients.
12. A dry premix and/or a dry infant food formulation comprising at least one powderous composition according to any one of claims 1 – 10.
13. Process for production of a composition according to any one of claims 1 – 10, comprising the steps: preparing a water phase at ambient temperature which comprises: a) the at least one hydrocolloid, 5 b) water, and c) optionally the at least one auxiliary agent; heating the water phase to a temperature of between 40 and 90 ºC; adding lutein to the heated water phase with dispersing to form a suspension; optionally followed by a homogenizing process; and 10 drying the suspension.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13161534 | 2013-03-28 | ||
EP13161534.6 | 2013-03-28 | ||
PCT/EP2014/056126 WO2014154788A1 (en) | 2013-03-28 | 2014-03-27 | Lutein composition suitable for infant food formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
NZ713087A NZ713087A (en) | 2020-09-25 |
NZ713087B2 true NZ713087B2 (en) | 2021-01-06 |
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