NZ711096A - Dcc mediated coupling for halofenate manufacture - Google Patents

Dcc mediated coupling for halofenate manufacture

Info

Publication number
NZ711096A
NZ711096A NZ711096A NZ71109613A NZ711096A NZ 711096 A NZ711096 A NZ 711096A NZ 711096 A NZ711096 A NZ 711096A NZ 71109613 A NZ71109613 A NZ 71109613A NZ 711096 A NZ711096 A NZ 711096A
Authority
NZ
New Zealand
Prior art keywords
halofenate
manufacture
mediated coupling
compound
formula
Prior art date
Application number
NZ711096A
Inventor
Jiangao Song
Original Assignee
Cymabay Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cymabay Therapeutics Inc filed Critical Cymabay Therapeutics Inc
Publication of NZ711096A publication Critical patent/NZ711096A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

The present application discloses a process for the preparation of a halofenate compound of the formula (III) or a salt thereof : wherein R, X and X’ are as defined herein, the process comprising contacting a compound of formula (la) with a compound of formula (lb) and Ν,Ν’-dicyclohexylcarbodiimide under conditions sufficient to form the compound of formula (III).
NZ711096A 2013-01-18 2013-01-18 Dcc mediated coupling for halofenate manufacture NZ711096A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2013/022213 WO2014113022A1 (en) 2013-01-18 2013-01-18 Dcc mediated coupling for halofenate manufacture

Publications (1)

Publication Number Publication Date
NZ711096A true NZ711096A (en) 2016-10-28

Family

ID=51209969

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ711096A NZ711096A (en) 2013-01-18 2013-01-18 Dcc mediated coupling for halofenate manufacture

Country Status (9)

Country Link
EP (1) EP2945926A4 (en)
CN (1) CN105143172B (en)
AU (1) AU2013374358B2 (en)
CA (1) CA2901353A1 (en)
EA (1) EA028385B1 (en)
HK (1) HK1211020A1 (en)
NZ (1) NZ711096A (en)
WO (1) WO2014113022A1 (en)
ZA (1) ZA201505919B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3517050A (en) * 1966-10-03 1970-06-23 Merck & Co Inc Ester and amide derivative of (3-trifluoromethylphenoxy) (4 - halophenyl)acetic acid
US7432394B2 (en) * 2005-09-23 2008-10-07 Metabolex, Inc. Resolution of α-(phenoxy) phenylacetic acid derivatives with naphthyl-alkylamines
WO2009121940A1 (en) * 2008-04-03 2009-10-08 Janssen Pharmaceutica Nv Process for the preparation of (-)-(4-chloro-phenyl)-(3-trifluoromethyl-phenoxy)-acetic acid 2-acetylamino-ethyl ester

Also Published As

Publication number Publication date
CN105143172A (en) 2015-12-09
AU2013374358A1 (en) 2015-09-03
EP2945926A4 (en) 2016-09-14
WO2014113022A1 (en) 2014-07-24
CN105143172B (en) 2016-12-14
AU2013374358B2 (en) 2017-06-08
ZA201505919B (en) 2017-05-31
HK1211020A1 (en) 2016-05-13
CA2901353A1 (en) 2014-07-24
EA201591348A1 (en) 2016-01-29
EA028385B1 (en) 2017-11-30
EP2945926A1 (en) 2015-11-25

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Legal Events

Date Code Title Description
PSEA Patent sealed
ASS Change of ownership

Owner name: CYMABAY THERAPEUTICS, INC., US

Effective date: 20170309

Owner name: DIATEX, INC., NZ

Effective date: 20170309

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 18 JAN 2019 BY CPA GLOBAL

Effective date: 20171207

LAPS Patent lapsed