NZ621148B2 - Sterilant system - Google Patents

Abstract

multi-part sterilant system (12) which has a first part (4) with a first reagent in a carrier medium in a first container (6) and a second part (8) with a second reagent in a carrier medium in a second container (10). The first reagent and the second reagent will react to provide a sterilising composition when the first part (4) is mixed with the second part (8). The system has a pump head (2) with a peristaltic pump member (22). The first container (6) has a first-part dispensing tube (16) extending from its interior and disposed through the pump head (2). The second container (10) has a second-part dispensing tube (18) extending from its interior and disposed through the pump head (2). The peristaltic pump member (22) when actuated acts on both the first-part dispensing tube (16) and the second-part dispensing tube (18) so as simultaneously to pump substantially equal volumes of the first part (4) and the second part (8). position when the first part (4) is mixed with the second part (8). The system has a pump head (2) with a peristaltic pump member (22). The first container (6) has a first-part dispensing tube (16) extending from its interior and disposed through the pump head (2). The second container (10) has a second-part dispensing tube (18) extending from its interior and disposed through the pump head (2). The peristaltic pump member (22) when actuated acts on both the first-part dispensing tube (16) and the second-part dispensing tube (18) so as simultaneously to pump substantially equal volumes of the first part (4) and the second part (8).

Description

W0 2013/030597 _ 1 _ STERILANT SYSTEM OUND a. Field of the Invention The present invention relates to a sterilant system and method for sterilising surfaces. b. Related Art Two-part sterilising solutions are used in applications where the active sterilising ingredient is unstable over time. The solution is therefore prepared in situ shortly before it is to be used. A particularly important sterilising agent is chlorine dioxide (0'02), which may be formed from mixtures of s reagents including: chlorite and acid; chlorate, peroxide and acid; and chlorite, hypochlorite, and a suitable buffer. Chlorine dioxide has excellent sterilising and bactericidal properties, and oral ion in man and animals has been shown to be relatively safe. describes a two part sterilant system having two reagents, each of which is put up in an aqueous medium in its own container. The aqueous media contain a foam promoter, and actuation of a single trigger dispenses each part as a foam. Mixing of the foams allows the reagents to react together to form a ant such as CIOz in situ.

The effectiveness of two-part sterilant systems in conventional trigger sprayers can be reduced if the spray action does not result in the delivery of an identical volume of each reagent medium, resulting in an excess of one reagent in the mixture. Delivery of different s is particularly likely to result when the dispensed media are of ent ities.

SUMMARY OF THE INVENTION Aspects of the invention are specified in the independent . Preferred features are ied in the dependent claims. 2012/052154 The invention allows plural volumes of fluid to be evenly pumped as equal volumes from two or more sources irrespective of differences in viscosity. r advantage of the invention over conventional multi-component fluid pumps is that it ensures clean delivery of each fluid. Prior art sterilant apparatuses typically have pistons and require use of silicone oil or a similar lubricant. Such lubricants can contaminate the fluids being pumped. In the present invention, silicone and other lubricants are not required, and the fluids being pumped are isolated from contact with the pump member.

W0 30597 _ 3 _ BRIEF DESCRIPTION OF THE GS The invention will now be further described, by way of example only, with reference to the ing drawings, in which: Figure 1 is a cutaway view of a pump apparatus of the sterilant system of Figure 6; Figures 2 and 3 show, respectively, the trigger and the peristaltic pump member of the assembly of Figure 4; Figure 4 is a view of the assembled trigger and peristaltic pump member of the apparatus of Figure 1; Figures 5a-5c show partial side views of the apparatus of Figure 1; Figures 6 and 7 illustrate a multi-part sterilant system in accordance with an aspect of the invention; Figure 8 shows a multi-part sterilant system in accordance with another embodiment of the invention; Figure 9 shows a multi-part sterilant system in accordance with a further ment of the invention; Figures 10 and 11 show, respectively, a pump head and a container g of a multi-part sterilant system in accordance with a further embodiment of the invention; Figure 12 shows a refill comprising collapsible containers suitable for insertion into the container g of Figure 11; Figure 13 shows a collar portion of a refill, for securing collapsible W0 2013/030597 _ 4 _ containers together, according to a further embodiment of the invention; Figure 14 shows a collapsible container suitable for engaging with the collar portion of Figure 13; and Figures 15-17 rate other embodiments of the invention.

DETAILED DESCRIPTION Referring to Figure 1, a pump apparatus 2 includes a pump head 20, a peristaltic pump member 22, and a plurality of dispensing tubes 16,18 disposed through the pump head 20. In this embodiment, the peristaltic pump member 22 is a rotor which is rotatably housed within the pump head 20; however, it will be understood that other types of altic pump member 22 could be used, for example a translational pump member. In this example, two sing tubes 16,18 are provided side by side, for simultaneously dispensing two s or gels. Three or more dispensing tubes could be used in alternative embodiments, for simultaneously dispensing a ponding number of fluids.

When actuated, the altic pump member 22 acts simultaneously on each of the dispensing tubes 16,18, in this embodiment via one or more ers 14. Two impellers 14a,14b are illustrated. Rotation of the pump member 22 causes at least one of the impellers 14 to act on each of the dispensing tubes 16,18 so as simultaneously to pump a fluid through each dispensing tube.

Each dispensing tube 16,18 is squeezed by the impeller 14 against an inner surface of the pump head 20, and as the pump member 22 turns, the impeller 14 drives fluid ahead of it through the dispensing tubes. Because the volume squeezed out by the impeller 14 is independent of the viscosity of the fluid within a sing tube, a substantially equal volume of fluid is pumped through each dispensing tube 16,18 regardless of viscosity. The dispensing tubes 16,18 are elastomeric at least in the region where the impeller 14 acts upon them, to ensure that the tubes return to their original cross-sectional shape when not acted upon WO 30597 _ 5 _ by an impeller. In a preferred embodiment, each dispensing tube 16, 18 is elastomeric along its entire length. In this embodiment, each dispensing tube 16, 18 is of a unitary construction.

In the present example, the pump head 20 is provided with a nozzle housing 34.

The dispensing tubes 16,18 ate at a nozzle 36, secured in the nozzle housing 34 through which fluids from both tubes are dispensed. The fluids may mix substantially at the point of exit from the nozzle 36 or some distance . In other embodiments, each dispensing tube terminates in a separate nozzle outlet so that mixing of fluids does not occur until after the fluids have been dispensed by the pump apparatus.

The exemplified pump apparatus 2 includes a -operated trigger 24 which is pivotally mounted to the pump head 20 and provided with a return spring 32 which urges the trigger 24 to an extended position. A user pulls the trigger 24 to actuate the peristaltic pump member 22 as will be described below.

Referring now to Figure 2, the exemplified peristaltic pump member 22 comprises two opposed drive wheels 40 which are connected together by the impellers 14.

The outer face of each drive wheel 40 is provided with ratchet es 30 which are upstanding from nt transitional flat surfaces 42. Each transitional flat surface 42 slopes evenly between an outer edge of one ratchet surface and an inner edge of an adjacent ratchet surface. In this embodiment the r 24 (Figure 3) is generally symmetric about a vertical axis, having a front n 46 and a pair of opposed side arms 44. Each side arm 44 is provided with an inwardly-directed pawl 28 for engagement with a ratchet surface 30 of the pump member 22 when the pump member 22 is housed within the pump head 20 between the arms 44 of the trigger 24 (Figure 4).

Figures 5a-5c show stages of operation of the pump apparatus. Starting from a fully extended position, a user squeezes the trigger 24 which pivots about a pin 26.

Each pawl 28 moves over a sloping transitional surface 42 until it abuts a ratchet surface 30 (Figure 5a). r squeezing of the trigger causes each pawl 28 to W0 2013/030597 _ 6 _ push against a ratchet surface 30 and drive the pump member anticlockwise as viewed. This turning first brings one of the impellers 14a simultaneously into contact with both dispensing tubes 16,18, and then causes the impeller 14a to begin pumping substantially equal volumes of fluid from each dispensing tube (Figure 5b). After the r has been fully pulled and released by the user, the return spring 32 brings the trigger back to its fully extended position, causing each pawl 28 to disengage from a ratchet surface 30 and pass back over the sloping tional surface 42 (Figure So) until it drops over an adjacent ratchet surface . During the trigger’s return, the pump member 22 does not move and pumping stops. A further ion of the trigger repeats the pumping process. In this embodiment, each drive wheel 40 has five ratchet surfaces 30. In other embodiments, the number of ratchet surfaces may be selected to permit reliable pumping of smaller volumes of fluids; for example by allowing a user ally to pull the trigger only half way towards the pump housing before releasing it. In other embodiments the number of ratchet surfaces 30 may be ed to provide desired increments/doses or multiples of up to 20-30.

Referring now to Figures 6 and 7, a red ment of the ion provides a two-part ant system 12 which incorporates the previously- bed peristaltic pump apparatus. The sterilant system 12 comprises a first part 4 and a second part 8. The first part 4 is in a first container 6 and comprises a first reagent in a carrier medium. The second part 8 is in a second container 10 and comprises a second t in a carrier medium. The first reagent and the second reagent react when the first and second parts are mixed, to provide a sterilising composition. Those skilled in the art of sterilant formulations will understand that the first and second reagents may be selected from a variety of substances. In a preferred embodiment the reagents react to produce CIOz. The first part may, for example, comprise an aqueous solution of a chlorite such as sodium chlorite, and the second part may se an aqueous acid or mixture of acids.

The sterilant system 12 has a pump head 20 with a peristaltic pump member 22.

The first 6 and second 10 containers in this embodiment are housed in a container _ 7 _ housing 38 which is secured to the pump head 20 by means of a securing feature 48 on the pump head which engages with an internal surface of the container housing 38. In one embodiment, the securing feature is a locking it, and once the container housing is engaged, it is not removable; the ant system 12 is disposable and will be discarded once the contents have been discharged. In alternative embodiments, the container housing 38 and the ners 6, 10 can be exchanged to permit refilling of the contents.

The first ner 6 has a first-part dispensing tube 16 extending from its interior and disposed through the pump head 20. The second container 10 has a second- part dispensing tube 18 extending from its or and disposed through the pump head 20. When the peristaltic pump member 22 is actuated by a user operating the trigger 24, the pump member 22 acts simultaneously on both the first-part dispensing tube 16 and the second-part dispensing tube 18, as described with reference to Figures 1-5, so as simultaneously to pump substantially equal volumes of the first part 4 and the second part 8 as a spray 50 of liquid, gel or foam.

In this ment, the first-part dispensing tube 16 and the second-part dispensing tube 18 are ted together at their free ends to a nozzle 36 through which is pumped a mixture of the first part 4 and the second part 8 when the pump member 22 is actuated. In the embodiment of Figure 8, each dispensing tube 16,18 has its own nozzle 36a,36b so that the first part and the second part are pumped as separate sprays or jets of fluid which will be mixed in situ, for example by a user rubbing his hands together when the system is a hand sanitizer or hand cleaner, or with a cloth or wipe when the system is used to sterilize a surface, for example a surface in a hospital or other clinical environment.

It will be appreciated that, within practical limits, any number of dispensing tubes may be employed for aneously dispensing a plurality of fluids. The ion allows a y of different reagents and/or ingredients or additives to be combined at or shortly before the point of delivery. Thus, components which individually have desirable properties but which may be unstable when stored in solution together may be employed in the multi-part system. A practical limit of up to about 10 dispensing tubes and associated containers is envisaged; for example 4-6 tubes, or for particularly complex systems, 7-9 tubes.

Referring now to Figure 9, an embodiment of a multi-part sterilant system 12 is rated. This system is similar to the system of Figures 6-8, but includes a third part 52 in a third container 54, with a third dispensing tube 56. Equal volumes of each part 4,8,52 are simultaneously dispensed when the trigger 24 is squeezed, via respective nozzles 36a,b,c. The first part and the second part may include reagents which react when mixed to provide an oxidising sterilant composition, for example ClO2, and the third part may include additional components which may not be stable to long term exposure to either or both of the reagents. In this example, the third part comprises an alcohol, notably isopropanol, which provides additional antiseptic functionality. Other alcohols, or mixtures of alcohols, may be used.

To se the proportion of alcohol, or other desired component, in the dispensed mixture, it will be appreciated that additional sing tubes may be used. For example, a fourth dispensing tube may be used, and both the third and fourth dispensing tubes may be used to dispense l, providing up to 50% alcohol in the final mixture without alcohol being present in the first part or the second part. A fifth dispensing tube s up to 60% alcohol to be dispensed, and use of 10 tubes permits up to 80% alcohol to be dispensed. When a plurality of dispensing tubes are used to dispense the same component, for example l, this component may optionally be provided in fewer containers than the number of dispensing tubes for the component. For example, a single container may be used, in which two or more sing tubes are disposed. For efficiency, the volume of such a container is preferably increased in tion to the number of associated dispensing tubes so that each container is emptied after the same number of operations of the trigger.

Each container 6,10, 54 may be provided with a vent tube to connect the top of the container’s or to here to allow pressure equalisation within the W0 2013/030597 _ 9 _ container during the pumping process. The vent tubes may be provided with a non-return valve to ensure that air can enter but fluid cannot exit through the vent tubes. Alternatively, each container may be collapsible so that as fluid is pumped out, the internal volume of the ner contracts. The containers may be collapsible by being formed from a flexible material such as a thin plastics material, or by virtue of being provided with flexible joints or folds, for example s-fashion.

We have found that the size of the pump head needed may be reduced by using a plurality of first-part dispensing tubes 16 and second-part dispensing tubes 18. By using a plurality of dispensing tubes (for example, two or three) for each part, each tube may be of narrower al and external dimensions for delivery of the same volume as is achievable using a single tube of larger dimensions for each part.

The narrower tubes can conform to a smaller radius than wider tubes, which allows the radius of the peristaltic pump member 22 and pump head 20 to be correspondingly reduced, making it easier to hold and e. Each type of the plurality of dispensing tube may be housed in a single container; alternatively a ity of first containers 6 and/or second containers 10 may be provided. An ment which uses two first-part dispensing tubes 16a,16b and two second- part dispensing tubes 18a,18b is illustrated in Figure 15.

Figures 10 to 12 show an example of a multi-part sterilant system including sible containers. The pump head 20 is as bed previously and includes three dispensing tubes 16, 18, 56 extending from a base portion 58 of the pump head 20.

The container housing 38 is sized to receive a refill component 60 as described below and includes an opening 62 at a top of the housing 38. The container housing 38 is preferably made from a substantially rigid material, gh the container housing 38 may be at least partially deformable, at least to permit engagement of the housing 38 with the pump head 20.

Figure 12 shows an embodiment of a refill component 60 including a chassis or _ 10 _ collar portion 64 and three collapsible containers 66, 68, 70. The collapsible ners 66, 68, 70 perform substantially the same function as the containers 6, , 54 previously described and, in particular, each container 66, 68, 70 includes a reagent or part of the multi-part ant system. Each of the containers 66, 68, 70 is preferably made from a thin wall of a plastics material such as nyl chloride (PVC).

An opening (not shown) in an upper region of each of the ners 66, 68, 70 is in fluid communication with an aperture 72 in the collar portion 64. Preferably, the collar portion 64 includes the same number of apertures 72 as the number of containers 66, 68, 70. The apertures 72 are d such that when the openings in the containers 66, 68, 70 are aligned with the apertures 72, the containers 66, 68, 70 are held in a suitable arrangement beneath the collar 64. In this way, the collar portion 64 secures the containers in such a way that the dispensing tubes 16, 18, 56 may be inserted into the containers 66, 68, 70 through the apertures 72 in the collar 64, ting cross-contamination of the dispensing tubes 16, 18, 56 when replacing the refill 60.

The sterilant system is assembled by lowering the containers 66, 68, 70 into the container housing 38 and inserting the dispensing tubes 16, 18, 56 into the containers 66, 68, 70 h the apertures 72 in the collar 64. The collar portion 64 engages with one or both of the base portion 58 of the pump head 20 and the opening 62 of the ner housing 38, such that the containers 66, 68, 70 are substantially suspended within the housing 38.

As liquid is drawn from the containers 66, 68, 70, through actuation of the trigger 24 and pump member 22, the containers 66, 68, 70 collapse. This provides a system that minimises or prevents the evaporation of liquid and the release of odours from the containers 66, 68, 70, which is particular desirable in the case of more volatile reagents that may be used in the sterilant system.

It is envisaged that the pump head 20 and container housing 38 will be , and the refill component 60 ed as described above. It is, therefore, _ 11 _ able to supply the refill 60 with a seal 74 covering the apertures 72 in the collar 64. The seal 74 would then be removed during ly of the sterilant system. Preferably the refill component 60 is ed in a vely rigid box or container 76, such as a ard box, to prevent deformation of the collapsible containers 66, 68, 70.

Figures 13 and 14 show a collar portion 78 and collapsible container 80 according to a further embodiment of the invention.

The collar portion 78 (Figure 13) is sized to engage with one or both of the base portion 58 of the pump head 20 and the opening 62 of the container housing 38, and the collar 78 includes three slots 82, each slot 82 extending inwards from an edge of the collar 78. The slots 82 are sized to receive a neck portion 84 of a collapsible container 80. The collapsible container 80 (Figure 14) is substantially the same as the collapsible containers 66, 68, 70 previously described. The container 80 includes a neck portion 84 extending from an upper region of the container 80, the neck portion 84 having a lip 86 around a top edge furthest from a body 88 of the container.

The neck portion 84 and lip 86 of the container 80 are sized to be received within a slot 82 in the collar 78. When the neck portion 84 is fully engaged in the collar 78, the lip 86 rests against a surface of the collar 78, ng the container 80 to be suspended from the collar 78.

To seal the container 80 during transport and storage, a bung 88 may be inserted into the top of the neck portion 84. This bung 88 can then be removed during ly of the sterilant system to allow a dispensing tube 16 to be inserted into the container 80.

Referring now to Figure 16, a foot-operated embodiment of the invention is illustrated. This permits the weight of the pump mechanism, including reagents and containers 6,10 to be supported on the ground, ng a user to carry only the pump head 20. In this ment, the peristaltic pump member 22 is operated by the action of a user’s foot on a d 65 which is return-biased by a spring 67. A spring-loaded catch 69 on the end of the foot pad pushes the pump ratchet to turn the pump member. The containers 6,8 are removable and replaceable, and are connected to tubes in the peristaltic pump member 22 by a connector 71 on the containers and a corresponding connector 73 on the pump member. The pump head 20 receives pumped fluids via a supply hose 59. In this embodiment, the supply hose 59 is detachable from the footpad and connectable via a hose plug 61 and hose socket 63. The hose 59 may be detached for replacement or cleaning of the pump head 20.

In the embodiment of Figure 17, an alternative hand-operated trigger lever 75 is used to drive the peristaltic pump head 22.

The invention allows plural volumes of reagents to be evenly pumped as equal volumes from two or more s irrespective of differences in viscosity, to form a sterilising composition.

Another advantage of the invention over conventional component fluid pumps is that it ensures clean delivery of each reagent fluid. Prior art sterilant apparatuses typically have pistons and require use of silicone oil or a r lubricant. Such lubricants can contaminate the fluids being pumped. In the present invention, ne and other lubricants are not required, and the fluids being pumped are isolated from contact with the pump member.

Although the invention has been described with particular nce to a disposable sterilant system, it will be understood that it is not limited to this embodiment. Instead of a finger-operated trigger, the peristaltic pump member may be actuated by a motorised trigger. The trigger may be manually operated by a user, or may be operated automatically in response to a proximity sensor detecting when an object is brought sufficiently close to the nozzle or nozzles.

Such embodiments may include a counter-top dispenser, an tic unted dispenser, and a personal (body-mounted) dispenser. _ 13 _ It is iated that n features of the invention, which are, for clarity, described in the context of separate embodiments, may also be provided in combination in a single embodiment. Conversely, various features of the invention which are, for brevity, described in the context of a single embodiment, may also be provided separately, or in any suitable combination.

Claims (14)

1. A multi-part sterilant system comprising: a first part sing a first reagent in a carrier medium in a first container; 5 a second part sing a second reagent in a r medium in a second container; wherein the first reagent and the second reagent will react to provide a sterilising composition when the first part is mixed with the second part; a pump head having a peristaltic pump member; 10 the first container having a first-part dispensing tube extending from its or and disposed through the pump head; the second container having a second-part dispensing tube extending from its interior and disposed through the pump head; wherein the peristaltic pump member when actuated acts on both the first- 15 part dispensing tube and the second-part dispensing tube so as simultaneously to pump substantially equal volumes of the first part and the second part.

2. A system according to claim 1, further comprising a pawl and a ratchet member for driving the peristaltic pump member, the ratchet member provided 20 with a plurality of ratchet surfaces which are engageable by the pawl.

3. A system according to claim 2, wherein the peristaltic pump member is ed with 4-30 ratchet surfaces, preferably 4-20 ratchet surfaces. 25

4. A system according to any preceding claim, wherein the system is incorporated in one of a counter top ser, an automatic wall-mounted dispenser, a foot-operated ser, a hand-operated dispenser, and a personal, body-mounted, dispenser. 30

5. A system ing to any preceding claim, which has from two to 10 dispensing tubes.

6. A system according to any preceding claim, further comprising: a third part comprising a fluid in a third container; the third container having a third dispensing tube extending from its interior and disposed through the pump head; wherein the peristaltic pump member when actuated acts on the part 5 dispensing tube, the second-part dispensing tube and the third dispensing tube so as simultaneously to pump substantially equal volumes of the first part, the second part and the third part.

7. A system according to claim 6, wherein the first reagent and the second 10 reagent will react when mixed to produce an oxidising sterilant composition, and wherein the third part ses an alcohol or mixture of alcohols.

8. A system according to any preceding claim, wherein the first container and the second ner are collapsible.

9. A system according to any preceding claim, wherein at least two first-part dispensing tubes and at least two second-part dispensing tubes are provided for dispensing, respectively, the first part and the second part. 20

10. A system according to any ing claim, wherein the first reagent and the second reagent react to produce ne dioxide when the first part is mixed with the second part.

11. A system according to any preceding claim, wherein the first container and 25 the second container are permanently secured to the pump head so that they are not refillable.

12. A system according to any of claims 1-10, wherein each container is provided in a housing which is releasably secured to the pump head.

13. A system according to claim 12, wherein each container is sible and is d to a collar member, the collar member having, for each container, an opening which is d with an opening of the container to receive a corresponding dispensing tube when the pump head is attached to the housing.

14. A system according to claim 13, wherein the open end of each container has a neck portion and a lip, and wherein each g in the collar member is 5 dimensioned to support the lip of a container and has a slot portion which extends to an edge of the collar member for slidably receiving the neck portion of a container. $19. 1 0000000