NZ615437A - Compositions and methods for treating multi-drug resistant malaria - Google Patents
Compositions and methods for treating multi-drug resistant malariaInfo
- Publication number
- NZ615437A NZ615437A NZ615437A NZ61543711A NZ615437A NZ 615437 A NZ615437 A NZ 615437A NZ 615437 A NZ615437 A NZ 615437A NZ 61543711 A NZ61543711 A NZ 61543711A NZ 615437 A NZ615437 A NZ 615437A
- Authority
- NZ
- New Zealand
- Prior art keywords
- composition
- compositions
- methods
- luo han
- fruit extract
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- 239000003814 drug Substances 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title 1
- 201000004792 malaria Diseases 0.000 title 1
- 235000013399 edible fruits Nutrition 0.000 abstract 4
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 abstract 4
- 239000001512 FEMA 4601 Substances 0.000 abstract 3
- HELXLJCILKEWJH-SEAGSNCFSA-N Rebaudioside A Natural products O=C(O[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)[C@@]1(C)[C@@H]2[C@](C)([C@H]3[C@@]4(CC(=C)[C@@](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@H](O)[C@@H](CO)O5)(C4)CC3)CC2)CCC1 HELXLJCILKEWJH-SEAGSNCFSA-N 0.000 abstract 3
- HELXLJCILKEWJH-UHFFFAOYSA-N entered according to Sigma 01432 Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC(C1OC2C(C(O)C(O)C(CO)O2)O)OC(CO)C(O)C1OC1OC(CO)C(O)C(O)C1O HELXLJCILKEWJH-UHFFFAOYSA-N 0.000 abstract 3
- 235000019203 rebaudioside A Nutrition 0.000 abstract 3
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 241000544066 Stevia Species 0.000 abstract 1
- 230000000078 anti-malarial effect Effects 0.000 abstract 1
- 239000003430 antimalarial agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Disclosed is the use of a composition in the manufacture of a medicament for the treatment of a malarial infection in an individual, wherein the composition comprises a Luo Han fruit extract and an acceptable carrier. Also disclosed is the use of a composition in the manufacture of a medicament for the treatment of a malarial infection in an individual, wherein the composition comprises a Stevia leaf extract or rebaudioside A, a Luo Han fruit extract and an acceptable carrier. Disclosed is an antimalarial composition comprising a therapeutically effective amount of rebaudioside A, a therapeutically effective amount of a Luo Han fruit extract, and an acceptable carrier, wherein the rebaudioside A is present in a range between about 1% to 99% by weight of the total composition, and the Luo Han fruit extract is present in a range between about 1% to 99% by weight of the total composition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ711238A NZ711238A (en) | 2011-03-18 | 2011-09-10 | Compositions and methods for treating multi-drug resistant malaria |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161454246P | 2011-03-18 | 2011-03-18 | |
| PCT/IB2011/053962 WO2012127287A2 (en) | 2011-03-18 | 2011-09-10 | Compositions and methods for treating multi-drug resistant malaria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ615437A true NZ615437A (en) | 2015-08-28 |
Family
ID=46879820
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ615437A NZ615437A (en) | 2011-03-18 | 2011-09-10 | Compositions and methods for treating multi-drug resistant malaria |
| NZ711238A NZ711238A (en) | 2011-03-18 | 2011-09-10 | Compositions and methods for treating multi-drug resistant malaria |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ711238A NZ711238A (en) | 2011-03-18 | 2011-09-10 | Compositions and methods for treating multi-drug resistant malaria |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9943558B2 (en) |
| EP (1) | EP2685996B1 (en) |
| KR (2) | KR101803693B1 (en) |
| CN (2) | CN103930120B (en) |
| AP (2) | AP2013007155A0 (en) |
| AU (1) | AU2011363456B2 (en) |
| ES (1) | ES2596406T3 (en) |
| NZ (2) | NZ615437A (en) |
| WO (1) | WO2012127287A2 (en) |
| ZA (1) | ZA201307701B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016040555A1 (en) * | 2014-09-12 | 2016-03-17 | Malaria Global Initiative, Corp. | Malaria treatment kit and system |
| CN109762264A (en) * | 2017-11-09 | 2019-05-17 | 丹阳市日晟工业设备有限公司 | A kind of vehicle plastic part |
| CN109762224A (en) * | 2017-11-09 | 2019-05-17 | 丹阳市日晟工业设备有限公司 | A kind of automobile-used anti-static plastic part |
| CN109777029A (en) * | 2017-11-13 | 2019-05-21 | 丹阳市日晟工业设备有限公司 | A kind of console plastic fittings |
| ES2731554B2 (en) * | 2018-04-05 | 2020-10-20 | Univ Valladolid | INCLUSION COMPLEX OF NATURAL ORIGIN AND BIODAVAILABLE FOR THE TREATMENT OF DISEASES OF PARASITIC ORIGIN |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5104885A (en) * | 1990-03-13 | 1992-04-14 | Calspan Corporation | 5-(phenylalkoxy)primaquine and 5[(heterocycle)alkoxy] primaquine compounds and their use for treatment of malaria |
| JP3436317B2 (en) * | 1993-11-24 | 2003-08-11 | 大日本インキ化学工業株式会社 | Method for producing stevia sweetener |
| WO2001039749A2 (en) * | 1999-11-30 | 2001-06-07 | Panacea Biotec Limited | Fast dissolving composition with prolonged sweet taste |
| EP1255718A1 (en) * | 2000-02-01 | 2002-11-13 | Stevia APS | A substance for the use in a dietary supplementation or for the preparation of a medicament for the treatment of non-insulin dependent diabetes mellitus, hypertension and/or the metabolic syndrome |
| US20040009908A1 (en) | 2002-07-10 | 2004-01-15 | Stamler Jonathan S. | Methods for treating or preventing ischemic injury |
| CN100418524C (en) * | 2005-10-26 | 2008-09-17 | 重庆医药工业研究院有限责任公司 | Stable medicine composition of artemisinin or its derivative |
| US7776911B2 (en) * | 2005-11-07 | 2010-08-17 | Indian Institute Of Science | Antimalarial drug containing synergistic combination of curcumin and artemisinin |
| US8435588B2 (en) * | 2005-11-23 | 2013-05-07 | The Coca-Cola Company | High-potency sweetener composition with an anti-inflammatory agent and compositions sweetened therewith |
| US8709521B2 (en) * | 2007-05-22 | 2014-04-29 | The Coca-Cola Company | Sweetener compositions having enhanced sweetness and improved temporal and/or flavor profiles |
| CN101062077B (en) * | 2007-06-18 | 2011-04-06 | 石任兵 | Method for preparing stevia whole stevioside and stevia whole flavone at the same time |
| KR20090018876A (en) * | 2007-08-19 | 2009-02-24 | 전현철 | Sweet curcumin tea and sweet curcumin water |
| GB0718446D0 (en) * | 2007-09-21 | 2007-10-31 | Prendergast Patrick T | Compositions and methods for the treatment of infection |
| KR101531202B1 (en) | 2007-11-12 | 2015-06-24 | 산에이겐 에후.에후. 아이. 가부시키가이샤 | Method of improving sweetness qualities of stevia extract |
| AU2009234283B2 (en) * | 2008-04-11 | 2015-04-02 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Diterpene glycosides as natural solubilizers |
| US8124654B2 (en) | 2008-11-11 | 2012-02-28 | Immune Modulation, Inc. | Derivatives of hypoestoxide and related compounds |
-
2011
- 2011-09-10 NZ NZ615437A patent/NZ615437A/en not_active IP Right Cessation
- 2011-09-10 AP AP2013007155A patent/AP2013007155A0/en unknown
- 2011-09-10 CN CN201180070955.9A patent/CN103930120B/en not_active Expired - Fee Related
- 2011-09-10 KR KR1020177018008A patent/KR101803693B1/en active IP Right Grant
- 2011-09-10 WO PCT/IB2011/053962 patent/WO2012127287A2/en active Application Filing
- 2011-09-10 KR KR1020137026650A patent/KR101759767B1/en active IP Right Grant
- 2011-09-10 AU AU2011363456A patent/AU2011363456B2/en not_active Ceased
- 2011-09-10 EP EP11861334.8A patent/EP2685996B1/en active Active
- 2011-09-10 US US14/005,721 patent/US9943558B2/en not_active Expired - Fee Related
- 2011-09-10 CN CN201810036678.3A patent/CN108339001A/en active Pending
- 2011-09-10 NZ NZ711238A patent/NZ711238A/en not_active IP Right Cessation
- 2011-09-10 ES ES11861334.8T patent/ES2596406T3/en active Active
- 2011-09-10 AP AP2017009688A patent/AP2017009688A0/en unknown
-
2013
- 2013-10-16 ZA ZA2013/07701A patent/ZA201307701B/en unknown
-
2018
- 2018-03-16 US US15/923,646 patent/US20180207216A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20170081286A (en) | 2017-07-11 |
| KR101759767B1 (en) | 2017-07-19 |
| NZ711238A (en) | 2016-06-24 |
| AU2011363456B2 (en) | 2016-06-16 |
| ES2596406T3 (en) | 2017-01-09 |
| CN103930120B (en) | 2018-02-02 |
| EP2685996A4 (en) | 2014-12-17 |
| KR101803693B1 (en) | 2017-11-30 |
| EP2685996B1 (en) | 2016-07-20 |
| US20180207216A1 (en) | 2018-07-26 |
| AP2013007155A0 (en) | 2013-09-30 |
| US20140072663A1 (en) | 2014-03-13 |
| WO2012127287A2 (en) | 2012-09-27 |
| CN108339001A (en) | 2018-07-31 |
| WO2012127287A3 (en) | 2014-02-27 |
| US9943558B2 (en) | 2018-04-17 |
| CN103930120A (en) | 2014-07-16 |
| EP2685996A2 (en) | 2014-01-22 |
| KR20140013026A (en) | 2014-02-04 |
| AP2017009688A0 (en) | 2017-01-31 |
| ZA201307701B (en) | 2016-08-31 |
| AU2011363456A1 (en) | 2013-10-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 10 SEP 2018 BY PIPERS Effective date: 20160317 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 SEP 2019 BY PIPERS Effective date: 20180727 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 SEP 2020 BY PIPERS Effective date: 20190814 |
|
| LAPS | Patent lapsed |