NZ609888A - Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine - Google Patents

Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine

Info

Publication number
NZ609888A
NZ609888A NZ609888A NZ60988804A NZ609888A NZ 609888 A NZ609888 A NZ 609888A NZ 609888 A NZ609888 A NZ 609888A NZ 60988804 A NZ60988804 A NZ 60988804A NZ 609888 A NZ609888 A NZ 609888A
Authority
NZ
New Zealand
Prior art keywords
polysaccharide
protein
capsular
vaccine
capsular polysaccharide
Prior art date
Application number
NZ609888A
Inventor
Robert P Ryall
Original Assignee
Sanofi Pasteur Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Inc filed Critical Sanofi Pasteur Inc
Publication of NZ609888A publication Critical patent/NZ609888A/en

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Disclosed is the use of a multivalent meningococcal vaccine comprising a mixture of four distinct and separately made protein-capsular polysaccharide conjugates for the manufacture of a medicament for inducing a serum bactericidal antibody protective immune response against capsular polysaccharides of Neisseria meningitidis serogroups A, C, W-135 and Y in a human patient, wherein each of the conjugates comprises a purified capsular polysaccharide from a different serogroup of N. meningitidis conjugated to a carrier protein, further wherein said carrier protein is selected from the group consisting of diphtheria toxoid, CRM197 and tetanus toxoid, and wherein each capsular polysaccharide is selected from the group consisting of capsular polysaccharides from N. meningitidis serogroups A, C, W-135 and Y, further wherein each capsular polysaccharide is depolymerized to an average size of less than 100,000 daltons and each protein-polysaccharide conjugate has an average polysaccharide to protein ratio of 0.05 to 2.
NZ609888A 2003-05-07 2004-05-07 Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine NZ609888A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46858103P 2003-05-07 2003-05-07
NZ59606604 2004-05-07

Publications (1)

Publication Number Publication Date
NZ609888A true NZ609888A (en) 2014-11-28

Family

ID=52464933

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ609888A NZ609888A (en) 2003-05-07 2004-05-07 Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine

Country Status (1)

Country Link
NZ (1) NZ609888A (en)

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