NZ603751A - Composition for treating disease - Google Patents
Composition for treating diseaseInfo
- Publication number
- NZ603751A NZ603751A NZ603751A NZ60375109A NZ603751A NZ 603751 A NZ603751 A NZ 603751A NZ 603751 A NZ603751 A NZ 603751A NZ 60375109 A NZ60375109 A NZ 60375109A NZ 603751 A NZ603751 A NZ 603751A
- Authority
- NZ
- New Zealand
- Prior art keywords
- domain
- chain
- seq
- composition
- sequence identity
- Prior art date
Links
Abstract
603751 Disclosed is a kit comprising separately a humanized anti-CD4 antibody capable of activating CD4+CD25+ regulatory T cells and methotrexate, wherein the humanized anti-CD4 antibody comprises an H chain V domain, an L chain V domain and an IgG 1 constant domain, and wherein: (a) the H chain V domain compnses the sequences DCRMY, VISVKSENYGANYAESVRG and SYYRYDVGAWFAY, and the L chain V domain comprises the sequences RASKSVSTSGYSYIY, LASILES and QHSRELPWT; and/or (b) the H chain V domain has at least 80% sequence identity with SEQ ID No: 1 and the L chain V domain has at least 80% sequence identity with SEQ ID No: 2. Further disclosed is the therapeutic use of said combinations for treating rheumatic diseases such as rheumatoid arthritis.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0817809A GB0817809D0 (en) | 2008-09-29 | 2008-09-29 | Agent for treating disease |
GB0817810A GB0817810D0 (en) | 2008-09-29 | 2008-09-29 | Agent for treating disease |
GB0817811A GB0817811D0 (en) | 2008-09-29 | 2008-09-29 | Agent for treating disease |
PCT/EP2009/052810 WO2009112502A1 (en) | 2008-03-13 | 2009-03-10 | Agent for treating disease |
PCT/EP2009/052811 WO2009124815A1 (en) | 2008-03-13 | 2009-03-10 | Agent for treating disease |
PCT/EP2009/052809 WO2009121690A1 (en) | 2008-03-13 | 2009-03-10 | Agent for treating disease |
NZ59210209 | 2009-08-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ603751A true NZ603751A (en) | 2014-04-30 |
Family
ID=50624334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ603751A NZ603751A (en) | 2008-09-29 | 2009-08-31 | Composition for treating disease |
Country Status (1)
Country | Link |
---|---|
NZ (1) | NZ603751A (en) |
-
2009
- 2009-08-31 NZ NZ603751A patent/NZ603751A/en not_active IP Right Cessation
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