NZ603739A - Combination therapy with peptide epoxyketones - Google Patents

Combination therapy with peptide epoxyketones

Info

Publication number
NZ603739A
NZ603739A NZ603739A NZ60373909A NZ603739A NZ 603739 A NZ603739 A NZ 603739A NZ 603739 A NZ603739 A NZ 603739A NZ 60373909 A NZ60373909 A NZ 60373909A NZ 603739 A NZ603739 A NZ 603739A
Authority
NZ
New Zealand
Prior art keywords
medicament
combination therapy
combination
dexamethasone
administering
Prior art date
Application number
NZ603739A
Inventor
Christopher J Kirk
Susan D Demo
Mark K Bennett
Original Assignee
Onyx Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Onyx Therapeutics Inc filed Critical Onyx Therapeutics Inc
Publication of NZ603739A publication Critical patent/NZ603739A/en

Links

Abstract

ABSTRACT - 603739 The disclosure relates to the use of (1) a peptide epoxyketone proteasome inhibitor represented by the structural formula shown herein, or a pharmaceutically acceptable salt thereof; and (2) dexamethasone, in combination, for the manufacture of a medicament for the treatment of multiple myeloma; wherein the medicament is formulated for administration of the peptide epoxyketone proteasome inhibitor and the dexamethasone within about 5 minutes to within about 48 hours of one another; and wherein the efficacy shown by administering (1) and (2) in combination is greater than the efficacy shown by administering either of (1) or (2) alone; and wherein the medicament may further comprises lenalidomide.
NZ603739A 2008-10-21 2009-10-21 Combination therapy with peptide epoxyketones NZ603739A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19694508P 2008-10-21 2008-10-21
NZ59273109 2009-10-21

Publications (1)

Publication Number Publication Date
NZ603739A true NZ603739A (en) 2014-02-28

Family

ID=50624311

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ603739A NZ603739A (en) 2008-10-21 2009-10-21 Combination therapy with peptide epoxyketones

Country Status (1)

Country Link
NZ (1) NZ603739A (en)

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