NZ601363A - Biaryl pde4 inhibitors for treating inflammation - Google Patents

Biaryl pde4 inhibitors for treating inflammation

Info

Publication number
NZ601363A
NZ601363A NZ601363A NZ60136308A NZ601363A NZ 601363 A NZ601363 A NZ 601363A NZ 601363 A NZ601363 A NZ 601363A NZ 60136308 A NZ60136308 A NZ 60136308A NZ 601363 A NZ601363 A NZ 601363A
Authority
NZ
New Zealand
Prior art keywords
compounds
pde4 inhibitors
ylmethyl
biphenyl
fluoro
Prior art date
Application number
NZ601363A
Inventor
Jasbir Singh
Mark E Gurney
Alex Burgin
Vincent Sandanayaka
Alexander Kiselyov
Adalie Motta
Gary Shultz
Georgeta Hategan
Timothy Hagen
Original Assignee
Decode Genetics Ehf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Decode Genetics Ehf filed Critical Decode Genetics Ehf
Publication of NZ601363A publication Critical patent/NZ601363A/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

601363 Disclosed are biaryl compounds containing at least one further ring. The compounds are PDE4 inhibitors useful for the treatment and prevention of stroke, myocardial infarct and cardiovascular inflammatory diseases and disorders. The compounds have general formula (I). Examples of compounds of the invention are: 3-Amino-5-(3’-chloro-2-fluoro-6-methoxy-biphenyl-3-ylmethyl)-phenol; [4-(3’-Acetyl-2-fluoro-6-methoxy-biphenyl-3-ylmethyl)-phenyl]-methyl-amine hydrochloride and 4-(3’-Acetyl-2-fluoro-6-methoxy-biphenyl-3-ylmethyl)-benzenesulfinic acid amide.
NZ601363A 2007-11-21 2008-11-20 Biaryl pde4 inhibitors for treating inflammation NZ601363A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98955107P 2007-11-21 2007-11-21
NZ58628108 2008-11-20

Publications (1)

Publication Number Publication Date
NZ601363A true NZ601363A (en) 2014-03-28

Family

ID=50542734

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ601363A NZ601363A (en) 2007-11-21 2008-11-20 Biaryl pde4 inhibitors for treating inflammation

Country Status (1)

Country Link
NZ (1) NZ601363A (en)

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Legal Events

Date Code Title Description
S38C Proceedings under section 38 (amendment of specification with leave of commissioner): specification amended
PSEA Patent sealed
S38C Proceedings under section 38 (amendment of specification with leave of commissioner): specification amended
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 20 NOV 2015 BY CPA GLOBAL

Effective date: 20141031

LAPS Patent lapsed