NZ591989A - Prion-specific peptide reagents - Google Patents

Prion-specific peptide reagents

Info

Publication number
NZ591989A
NZ591989A NZ591989A NZ59198904A NZ591989A NZ 591989 A NZ591989 A NZ 591989A NZ 591989 A NZ591989 A NZ 591989A NZ 59198904 A NZ59198904 A NZ 59198904A NZ 591989 A NZ591989 A NZ 591989A
Authority
NZ
New Zealand
Prior art keywords
peptide
peptoid
sequence
prion
amino acid
Prior art date
Application number
NZ591989A
Inventor
Melissa D Michelitsch
Celine Hu
Ronald N Zuckermann
Michael D Connolly
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Priority claimed from PCT/US2004/026363 external-priority patent/WO2005016127A2/en
Publication of NZ591989A publication Critical patent/NZ591989A/en

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Provided is an isolated peptide reagent comprising a peptide or a peptoid or a multimer comprising a plurality of said peptide or peptoid, wherein said peptide reagent interacts preferentially with a pathogenic form of a conformational disease protein as compared to a non-pathogenic form of the conformational disease protein, and wherein said peptide or said peptoid consists of up to 100 amino acid residues in length comprising a sequence QWNKPSKPKTN or a variant of said sequence wherein one or two amino acids of said sequence selected from tryptophan, asparagine, lysine, proline, and threonine is/are substituted with another amino acid or N-substituted glycine residue. The peptide is useful in assays for binding specifically prion proteins.
NZ591989A 2003-08-13 2004-08-13 Prion-specific peptide reagents NZ591989A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49496203P 2003-08-13 2003-08-13
PCT/US2004/026363 WO2005016127A2 (en) 2003-08-13 2004-08-13 Prion-specific peptide reagents

Publications (1)

Publication Number Publication Date
NZ591989A true NZ591989A (en) 2012-12-21

Family

ID=38166674

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ591989A NZ591989A (en) 2003-08-13 2004-08-13 Prion-specific peptide reagents

Country Status (3)

Country Link
CN (1) CN1984669B (en)
NZ (1) NZ591989A (en)
ZA (1) ZA200601233B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023507828A (en) * 2019-12-20 2023-02-27 ステム バイオ カンパニー,リミテッド Pharmaceutical compositions containing prion protein-specific antibodies

Also Published As

Publication number Publication date
ZA200601233B (en) 2007-05-30
CN1984669A (en) 2007-06-20
CN1984669B (en) 2012-11-14

Similar Documents

Publication Publication Date Title
BRPI0616712B8 (en) method for amidating polypeptides with basic amino acid c-termini by specific endoproteases
ATE501169T1 (en) LACTOFERRIN PEPTIDES, SUITABLE AS CELL-PENETRATING PEPTIDES
EP2031063A3 (en) Modulators of odorant receptors
ATE485386T1 (en) CYSTEINE-CONTAINING PEPTIDE TAG FOR SITE-SPECIFIC CONJUGATION OF PROTEINS
ATE544780T1 (en) HYBRID POLYPEPTIDES WITH INSERTED SEQUENCE MOTIFS AND THEIR USES
EP2343318A3 (en) Antibodies binding to a C-terminal fragment of apolipoprotein E
DK2020604T3 (en) Ligand for the G protein-coupled receptor FPRL2
ATE368688T1 (en) PEPTIDES, THEIR PRODUCTION AND USE FOR BINDING IMMUNOGLOBULINS
WO2006076687A3 (en) Elisa assays using prion-specific peptide reagents
MX2009007070A (en) Transport molecules using reverse sequence hiv-tat polypeptides.
HK1093308A1 (en) Use of peptides derived from the b beta chain of human fibrinogen for the treatment of shock
DE60129239D1 (en) KIT AND PROCESS FOR DETERMINING PROTEIN ESM-1
DE60335726D1 (en) CHROMOPROTEIN AND FLUORO PROTEINS
ATE447612T1 (en) FLUORESCENT PROTEINS
DE602005025141D1 (en) Cell-penetrating peptides as carriers for molecules
DE60219645D1 (en) ANTIBODIES TO METASTIN AND ITS USE IN THE DIAGNOSIS OF PREGNANCY
WO2009086125A3 (en) Affinity tag nucleic acid and protein compositions, and processes for using same
DE60034888D1 (en) N-SUBSTITUTED L-AMINO ACIDS CONTAINING PEPTIDES FOR THE PREVENTION OF THE BETA-STRAND ASSOCIATION
NZ591989A (en) Prion-specific peptide reagents
ATE355302T1 (en) PEPTIDES CONTAINING N-SUBSTITUTED D-AMINO ACIDS FOR PREVENTING BETA STRAND ASSOCIATION
ATE294816T1 (en) NEW, PHYSIOLOGICALLY ACTIVE PEPTIDES AND THEIR USE.
MXPA05008535A (en) Identification and characterization of racemases, definition of protein signatures, and a test for detecting d-amino acid and for screening molecules capable of inhibiting the activity of racemase, especially proline racemase.
AR018045A1 (en) PLACENTARY PROTEIN 13 AND POLYPETIDE, DNA MOLECULA THAT CODIFIES THEM, ANTIBODIES ABLE TO LINK TO THEM, METHOD FOR DETECTION DECOMPLICATIONS RELATED TO PREGNANCY, RECOMBINANT METHOD FOR THE PRODUCTION OF DIAHA PROTECOEL AND A COMPLIANCE EQUIPMENT
ATE421698T1 (en) PORK INTRINSIC FACTOR
RU2007142850A (en) DED PEPTID AND ITS APPLICATION FOR IDENTIFICATION AND / OR CLEANING OF RECOMBINANT PROTEINS, VECTOR PDED

Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 6 YEARS UNTIL 13 AUG 2014 BY CPAGLOBAL

Effective date: 20130520

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 13 AUG 2017 BY AJ PARK

Effective date: 20150130

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 AUG 2018 BY AJ PARK

Effective date: 20170529

LAPS Patent lapsed