NZ588467A - Modified chaperonin 10 (CPN10) polypeptides and pattern recognition receptor (PRR) signalling - Google Patents
Modified chaperonin 10 (CPN10) polypeptides and pattern recognition receptor (PRR) signallingInfo
- Publication number
- NZ588467A NZ588467A NZ588467A NZ58846709A NZ588467A NZ 588467 A NZ588467 A NZ 588467A NZ 588467 A NZ588467 A NZ 588467A NZ 58846709 A NZ58846709 A NZ 58846709A NZ 588467 A NZ588467 A NZ 588467A
- Authority
- NZ
- New Zealand
- Prior art keywords
- polypeptides
- cpn10
- prr
- signalling
- pattern recognition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4715—Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
Abstract
Disclosed are isolated Cpn10 polypeptides possessing an increased affinity for a PRR ligand compared to Ala Cpn10 polypeptide. In a further embodiment, the present invention also relates to modified chaperonin 10 polypeptides, and to nucleic acids encoding the same and to compositions comprising such polypeptides and uses thereof.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/AU2008/000520 WO2009124333A1 (en) | 2008-04-11 | 2008-04-11 | Modified chaperonin 10 and prr signaling |
AU2009900613A AU2009900613A0 (en) | 2009-02-13 | Modified Cpn10 and PRR signalling | |
PCT/AU2009/000444 WO2009124353A1 (en) | 2008-04-11 | 2009-04-09 | Modified cpn10 and prr signalling |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ588467A true NZ588467A (en) | 2012-11-30 |
Family
ID=41161469
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ588467A NZ588467A (en) | 2008-04-11 | 2009-04-09 | Modified chaperonin 10 (CPN10) polypeptides and pattern recognition receptor (PRR) signalling |
Country Status (12)
Country | Link |
---|---|
US (1) | US9234019B2 (en) |
EP (1) | EP2265635A4 (en) |
JP (1) | JP2011519548A (en) |
KR (1) | KR20110005710A (en) |
CN (1) | CN102015757B (en) |
AU (1) | AU2009235953B2 (en) |
BR (1) | BRPI0911676A2 (en) |
CA (1) | CA2720617A1 (en) |
MX (1) | MX2010011169A (en) |
NZ (1) | NZ588467A (en) |
RU (1) | RU2010145972A (en) |
WO (1) | WO2009124353A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102711793A (en) * | 2009-10-09 | 2012-10-03 | 悉生物有限公司 | Chaperonin 10 variants |
MX347515B (en) * | 2010-04-01 | 2017-04-28 | Oncomed Pharmaceuticals Inc * | Frizzled-binding agents and uses thereof. |
EP2490021A1 (en) * | 2011-02-18 | 2012-08-22 | Biotempt B.V. | Modulators of PRR and GPCR signalling |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU684578B2 (en) | 1993-11-30 | 1997-12-18 | University Of Queensland, The | Antagonists to chaperonin 10 |
CN100406891C (en) * | 2001-06-27 | 2008-07-30 | 詹森药业有限公司 | EPF receptor assays, compounds and therapeutic compsns. |
AU2002952492A0 (en) * | 2002-11-06 | 2002-11-21 | Cbio Limited | Chaperonin 10 immunosuppression |
ATE548047T1 (en) * | 2004-01-16 | 2012-03-15 | Cbio Ltd | CHAPERONIN-10 MODULATION OF GREAT RECEPTOR-INDUCABLE CYTOKINE AND CHEMOKINE SECRETION |
MX2008000596A (en) * | 2005-07-11 | 2008-03-19 | Cbio Ltd | Chaperonin 10-induced immunomodulation. |
EP1937723B1 (en) * | 2005-08-31 | 2013-11-13 | Invion Limited | Modified chaperonin 10 |
EP1951282A4 (en) * | 2005-10-20 | 2009-09-02 | Cbio Ltd | Treatment of hypersensitivity |
-
2009
- 2009-04-09 CA CA2720617A patent/CA2720617A1/en not_active Abandoned
- 2009-04-09 MX MX2010011169A patent/MX2010011169A/en active IP Right Grant
- 2009-04-09 JP JP2011503310A patent/JP2011519548A/en active Pending
- 2009-04-09 NZ NZ588467A patent/NZ588467A/en not_active IP Right Cessation
- 2009-04-09 AU AU2009235953A patent/AU2009235953B2/en not_active Ceased
- 2009-04-09 EP EP20090730646 patent/EP2265635A4/en not_active Withdrawn
- 2009-04-09 US US12/934,980 patent/US9234019B2/en not_active Expired - Fee Related
- 2009-04-09 BR BRPI0911676A patent/BRPI0911676A2/en not_active IP Right Cessation
- 2009-04-09 CN CN200980112775.5A patent/CN102015757B/en not_active Expired - Fee Related
- 2009-04-09 RU RU2010145972/10A patent/RU2010145972A/en not_active Application Discontinuation
- 2009-04-09 WO PCT/AU2009/000444 patent/WO2009124353A1/en active Application Filing
- 2009-04-09 KR KR1020107025213A patent/KR20110005710A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2011519548A (en) | 2011-07-14 |
KR20110005710A (en) | 2011-01-18 |
WO2009124353A1 (en) | 2009-10-15 |
MX2010011169A (en) | 2011-03-01 |
BRPI0911676A2 (en) | 2016-11-29 |
RU2010145972A (en) | 2012-05-20 |
US9234019B2 (en) | 2016-01-12 |
EP2265635A1 (en) | 2010-12-29 |
WO2009124353A8 (en) | 2009-12-30 |
CA2720617A1 (en) | 2009-10-15 |
US20110082073A1 (en) | 2011-04-07 |
AU2009235953A1 (en) | 2009-10-15 |
CN102015757A (en) | 2011-04-13 |
EP2265635A4 (en) | 2013-02-20 |
AU2009235953B2 (en) | 2014-10-02 |
CN102015757B (en) | 2015-12-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PSEA | Patent sealed | ||
RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 09 APR 2016 BY CPA GLOBAL Effective date: 20130704 |
|
LAPS | Patent lapsed |