NZ580975A - Drug combination of beta 2 agonist and a progestin for the treatment of muscle loss - Google Patents
Drug combination of beta 2 agonist and a progestin for the treatment of muscle lossInfo
- Publication number
- NZ580975A NZ580975A NZ580975A NZ58097508A NZ580975A NZ 580975 A NZ580975 A NZ 580975A NZ 580975 A NZ580975 A NZ 580975A NZ 58097508 A NZ58097508 A NZ 58097508A NZ 580975 A NZ580975 A NZ 580975A
- Authority
- NZ
- New Zealand
- Prior art keywords
- agonist
- beta
- progestin
- treatment
- muscle loss
- Prior art date
Links
- 210000003205 muscle Anatomy 0.000 title abstract 4
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 title abstract 2
- 229940124748 beta 2 agonist Drugs 0.000 title abstract 2
- 239000000583 progesterone congener Substances 0.000 title abstract 2
- 239000000890 drug combination Substances 0.000 title 1
- 208000030507 AIDS Diseases 0.000 abstract 1
- 206010006895 Cachexia Diseases 0.000 abstract 1
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 229940125388 beta agonist Drugs 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960002848 formoterol Drugs 0.000 abstract 1
- BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 abstract 1
- QZZUEBNBZAPZLX-QFIPXVFZSA-N indacaterol Chemical compound N1C(=O)C=CC2=C1C(O)=CC=C2[C@@H](O)CNC1CC(C=C(C(=C2)CC)CC)=C2C1 QZZUEBNBZAPZLX-QFIPXVFZSA-N 0.000 abstract 1
- 229960004078 indacaterol Drugs 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229960001634 ritodrine Drugs 0.000 abstract 1
- IOVGROKTTNBUGK-SJCJKPOMSA-N ritodrine Chemical compound N([C@@H](C)[C@H](O)C=1C=CC(O)=CC=1)CCC1=CC=C(O)C=C1 IOVGROKTTNBUGK-SJCJKPOMSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Virology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0707930A GB0707930D0 (en) | 2007-04-24 | 2007-04-24 | New therapeutic use |
| GB0707931A GB0707931D0 (en) | 2007-04-24 | 2007-04-24 | New Therapeutic use |
| GB0710101A GB0710101D0 (en) | 2007-05-25 | 2007-05-25 | New Therapeutic use |
| PCT/GB2008/001452 WO2008129308A2 (en) | 2007-04-24 | 2008-04-24 | Drug combination and its use in the treatment of muscle loss |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ580975A true NZ580975A (en) | 2012-10-26 |
Family
ID=39639100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ580975A NZ580975A (en) | 2007-04-24 | 2008-04-24 | Drug combination of beta 2 agonist and a progestin for the treatment of muscle loss |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8653052B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2155180B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5627452B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101546977B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN104306381A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008240379B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0810461A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2721739C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2155180T3 (cg-RX-API-DMAC7.html) |
| EA (1) | EA018918B1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2592289T3 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1202262A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL201426A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2009011294A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ580975A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008129308A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1121111B1 (en) | 1998-10-15 | 2010-02-10 | Imperial Innovations Limited | Compounds for the treatment of weight loss |
| ATE552032T1 (de) | 2005-07-14 | 2012-04-15 | Lithera Inc | Verbesserte lipolytikum-formulierung mit hinhaltender wirkstofffreigabe für die arealbehandlung von fettgewebe |
| GB0624282D0 (en) | 2006-12-05 | 2007-01-10 | Cavalla David | Treatment of cachexia |
| UA111822C2 (uk) | 2010-11-24 | 2016-06-24 | Общєство С Огранічєнной Отвєтствєнностью "Новамедіка" | Монотерапевтичий препарат селективного ліпофільного бета-агоніста тривалої дії і спосіб косметичного лікування ожиріння і контурного випинання |
| KR101980180B1 (ko) * | 2014-08-05 | 2019-05-20 | 라퀄리아 파마 인코포레이티드 | 그렐린 수용체 작용제로서의 세린 유도체 |
| EP4090326B1 (en) * | 2020-01-13 | 2025-09-17 | Astromedical Biotechnology, Ltd. | Use of ketamine in the treatment of cachexia |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0308157B1 (en) | 1987-09-15 | 1997-02-26 | The Rowett Research Institute | Therapeutic applications of beta-adrenergic agonists |
| US7101576B2 (en) * | 2002-04-12 | 2006-09-05 | Elan Pharma International Limited | Nanoparticulate megestrol formulations |
| WO2003086354A1 (en) * | 2002-04-12 | 2003-10-23 | Elan Pharma International Ltd. | Nanoparticulate megestrol formulations |
| ES2245612B1 (es) * | 2004-06-29 | 2007-08-16 | Universidad De Barcelona | Nuevo uso terapeutico del formoterol. |
| EP1991270A4 (en) * | 2005-12-22 | 2009-12-02 | Anaborex Inc | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CACHEXIA |
| US7947579B2 (en) * | 2006-02-13 | 2011-05-24 | Stc.Unm | Method of making dense, conformal, ultra-thin cap layers for nanoporous low-k ILD by plasma assisted atomic layer deposition |
-
2008
- 2008-04-24 ES ES08737103.5T patent/ES2592289T3/es active Active
- 2008-04-24 BR BRPI0810461-1A2A patent/BRPI0810461A2/pt not_active IP Right Cessation
- 2008-04-24 MX MX2009011294A patent/MX2009011294A/es active IP Right Grant
- 2008-04-24 WO PCT/GB2008/001452 patent/WO2008129308A2/en not_active Ceased
- 2008-04-24 EP EP08737103.5A patent/EP2155180B1/en not_active Not-in-force
- 2008-04-24 AU AU2008240379A patent/AU2008240379B2/en not_active Ceased
- 2008-04-24 US US12/594,985 patent/US8653052B2/en not_active Expired - Fee Related
- 2008-04-24 CN CN201410490740.8A patent/CN104306381A/zh active Pending
- 2008-04-24 DK DK08737103.5T patent/DK2155180T3/en active
- 2008-04-24 CN CN200880012990A patent/CN101730547A/zh active Pending
- 2008-04-24 CA CA2721739A patent/CA2721739C/en not_active Expired - Fee Related
- 2008-04-24 JP JP2010504834A patent/JP5627452B2/ja not_active Expired - Fee Related
- 2008-04-24 NZ NZ580975A patent/NZ580975A/xx not_active IP Right Cessation
- 2008-04-24 EA EA200970957A patent/EA018918B1/ru not_active IP Right Cessation
- 2008-04-24 KR KR1020097024247A patent/KR101546977B1/ko not_active Expired - Fee Related
-
2009
- 2009-10-11 IL IL201426A patent/IL201426A/en not_active IP Right Cessation
-
2015
- 2015-03-19 HK HK15102807.2A patent/HK1202262A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008129308A2 (en) | 2008-10-30 |
| IL201426A (en) | 2016-09-29 |
| KR101546977B1 (ko) | 2015-08-24 |
| EA018918B1 (ru) | 2013-11-29 |
| CN101730547A (zh) | 2010-06-09 |
| IL201426A0 (en) | 2010-05-31 |
| US20100130456A1 (en) | 2010-05-27 |
| US8653052B2 (en) | 2014-02-18 |
| KR20100017205A (ko) | 2010-02-16 |
| HK1202262A1 (en) | 2015-09-25 |
| EA200970957A1 (ru) | 2010-04-30 |
| AU2008240379A1 (en) | 2008-10-30 |
| EP2155180A2 (en) | 2010-02-24 |
| ES2592289T3 (es) | 2016-11-29 |
| MX2009011294A (es) | 2010-01-29 |
| AU2008240379B2 (en) | 2012-10-04 |
| CA2721739A1 (en) | 2008-10-30 |
| BRPI0810461A2 (pt) | 2014-10-14 |
| JP5627452B2 (ja) | 2014-11-19 |
| CA2721739C (en) | 2016-08-23 |
| JP2010525044A (ja) | 2010-07-22 |
| DK2155180T3 (en) | 2016-09-12 |
| CN104306381A (zh) | 2015-01-28 |
| WO2008129308A3 (en) | 2009-12-17 |
| EP2155180B1 (en) | 2016-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 24 APR 2015 BY CPA GLOBAL Effective date: 20130205 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 24 APR 2016 BY PAVIS EG Effective date: 20150414 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 24 APR 2017 BY DR. STEFFEN SCHWARZ IPRIS AG Effective date: 20160414 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 24 APR 2018 BY DR. STEFFEN SCHWARZ IPRIS AG Effective date: 20170420 |
|
| LAPS | Patent lapsed |