NZ523208A - Antibodies that bind to tumor gene sequences - Google Patents

Antibodies that bind to tumor gene sequences

Info

Publication number
NZ523208A
NZ523208A NZ523208A NZ52320800A NZ523208A NZ 523208 A NZ523208 A NZ 523208A NZ 523208 A NZ523208 A NZ 523208A NZ 52320800 A NZ52320800 A NZ 52320800A NZ 523208 A NZ523208 A NZ 523208A
Authority
NZ
New Zealand
Prior art keywords
antibodies
bind
gene sequences
tumor gene
tumor
Prior art date
Application number
NZ523208A
Inventor
Avi J Ashkenazi
Audrey Goddard
Paul Godowski
Austin L Gurney
Kenneth J Hillan
Scot A Marsters
James Pan
Robert M Pitti
Margaret Ann Roy
Victoria Smith
Donna M Stone
Colin K Watanabe
William I Wood
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of NZ523208A publication Critical patent/NZ523208A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

An isolated antibody which binds to a PRO5725 polypeptide useful for the diagnosis and treatment of neoplastic cell growth and proliferation in mammals. Also disclosed is a composition of matter which comprises such an antibody in admixture with a pharmaceutically acceptable carrier as well as a method of diagnosing a tumor in a mammal comprising detecting the level of expression of a gene encoding a PRO5725 polypeptide. (62) Divided out of 513426
NZ523208A 1999-06-22 2000-02-11 Antibodies that bind to tumor gene sequences NZ523208A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14065099P 1999-06-22 1999-06-22

Publications (1)

Publication Number Publication Date
NZ523208A true NZ523208A (en) 2004-12-24

Family

ID=33538663

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ523208A NZ523208A (en) 1999-06-22 2000-02-11 Antibodies that bind to tumor gene sequences

Country Status (2)

Country Link
KR (1) KR100526723B1 (en)
NZ (1) NZ523208A (en)

Also Published As

Publication number Publication date
KR20040103921A (en) 2004-12-09
KR100526723B1 (en) 2005-11-09

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