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Priority claimed from US08/317,399external-prioritypatent/US5807884A/en
Application filed by Univ EmoryfiledCriticalUniv Emory
Publication of NZ511004ApublicationCriticalpatent/NZ511004A/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
A dithiocarbamate ester of formula ASC(S)B which prevents or minimizes the oxidation of a polyunsaturated fatty acid is used to treat cardiovascular disease or inflammatory disease wherein: A is a physiologically cleavable leading group other than a pharmaceutically acceptable cation; B is NR2R3; R2 and R3 are independently alkyl, (CHOH)n(CH2)nOH, -(CH2)n-CO2R4, hydroxyalkyl, alkenyl, alkyl-CO2H, alkenyl-CO2H, alkynyl-CO2H or aryl optionally substituted by NO2, CH3, t-butyl, CO2H, halo or p-OH or together R2 and R3 can form a bridge; n is 0 to 6 and R4 is alkyl, aryl, alkaryl, and aralkyl.
NZ511004A1994-05-101995-05-10Use of dithiocarbamate ester to treat cardiovascular or inflammatory diseases
NZ511004A
(en)
Process for producing 19-norsteroids comprising carbon chain substituted in 11beta position by amide or carbamagte group, as well as pharmaceutical compositions comprising such compounds as active ingredient
Derivatives of 3-quinuclidine esters, intermediates and process for their preparation, antimuscarinic pharmaceutical composition and method for treating chronic obstructive airways diseases or asthma