NZ501709A - Pharmaceutical compositions comprising a compound having affinity for FKB12, a neurotrophic factor and a pharmaceuticl carrier - Google Patents

Pharmaceutical compositions comprising a compound having affinity for FKB12, a neurotrophic factor and a pharmaceuticl carrier

Info

Publication number
NZ501709A
NZ501709A NZ501709A NZ50170996A NZ501709A NZ 501709 A NZ501709 A NZ 501709A NZ 501709 A NZ501709 A NZ 501709A NZ 50170996 A NZ50170996 A NZ 50170996A NZ 501709 A NZ501709 A NZ 501709A
Authority
NZ
New Zealand
Prior art keywords
compound
neurotrophic factor
compositions
pharmaceutical compositions
methods
Prior art date
Application number
NZ501709A
Inventor
David M Armistead
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Priority claimed from NZ310339A external-priority patent/NZ310339A/en
Publication of NZ501709A publication Critical patent/NZ501709A/en

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The application relates to methods and pharmaceutical compositions for stimulating the growth of neurites in nerve cells. The compositions comprise a neurotrophic amount of a compound of the formula below, where A is O, NH or Nalkyl; T is heteroaryl, aryl or substituted cyclohexyl, E is O, CH-U. J is H or alkyl, K is alkyl, benzyl or cyclohexylmethyl, or J and K together form a 7 membered heterocyclic ring and B, D and U are as defined in the specification. which binds to the FK-506 binding protein (FKBP) and a neurotrophic factor, such as nerve growth factor NGF. The methods comprise treating nerve cells with the above-described compositions or compositions comprising the FKBP binding compound without a neurotrophic factor. The methods can be used to promote repair of neuronal damage caused by disease or physical trauma.
NZ501709A 1995-06-08 1996-06-06 Pharmaceutical compositions comprising a compound having affinity for FKB12, a neurotrophic factor and a pharmaceuticl carrier NZ501709A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48600495A 1995-06-08 1995-06-08
NZ310339A NZ310339A (en) 1995-06-08 1996-06-06 Compositions for stimulating neurite growth comprising a neurotrophic amount of a compound with affinity for FKBP12 and a neurotrophic agent

Publications (1)

Publication Number Publication Date
NZ501709A true NZ501709A (en) 2000-10-27

Family

ID=26651728

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ501709A NZ501709A (en) 1995-06-08 1996-06-06 Pharmaceutical compositions comprising a compound having affinity for FKB12, a neurotrophic factor and a pharmaceuticl carrier

Country Status (1)

Country Link
NZ (1) NZ501709A (en)

Similar Documents

Publication Publication Date Title
NZ310339A (en) Compositions for stimulating neurite growth comprising a neurotrophic amount of a compound with affinity for FKBP12 and a neurotrophic agent
EA199900462A1 (en) METHODS AND COMPOSITIONS FOR STIMULATING GROWTH OF NONRITIS, USING CONNECTIONS WITH AFFINITY TO FKBP12 IN COMBINATION WITH NEUROTROPHIC FACTORS
EA199900464A1 (en) METHODS AND COMPOSITIONS FOR STIMULATING GROWTH OF NEURITES
MY124316A (en) Pyridazino quinoline compounds.
TR199902194T2 (en) Substituted nitrogen-containing heterocycles as +p38 protein kinase inhibitors.
NO923466L (en) Heterocyclic Compounds with 5 Sections, PROCEDURE PREPARATION, AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS
WO1997017329A1 (en) Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same
EP0058427A3 (en) Substituted phosphonamides, a process for preparing the same and a pharmaceutical composition which is useful in the treatment of hypertension
NO933248L (en) Cyclic urea derivatives, drugs containing these compounds, and process for their preparation
DE3760532D1 (en) Benzoûb¨thiophene and benzoûb¨furancarboxamide derivatives, processes for their preparation and therapeutical agents containing them
GEP20022678B (en) Bicyclic Heteroaromatic Compounds As Protein Tyrosine Kinase Inhibitors, their Pharmaceutical compositions and methods for Treatment
BG101110A (en) Substituted pyrimidine compounds and their application
BR0016150A (en) Compounds, compositions and methods for stimulating growth and neuronal elongation
MY101721A (en) 6-vinyl-furo-(3,4-c)-pyridine derivatives
NZ502820A (en) Heteroaryl or aryl substituted carboxylic acid or carboxamide derivatives optionally substituted with a sulphonamido group
NO922185D0 (en) 1-METHYL CARBAPENEME DERIVATIVES, PROCEDURES FOR PREPARING THEREOF, AND USE OF THE DERIVATIVES AS ANTIBIOTICS
ATE211474T1 (en) GALANTHAMIN DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE AS MEDICATIONS
PT83535B (en) METHOD FOR PREPARING PHARMACEUTICAL COMPOSITIONS CONTAINING AMINO ACID DERIVATIVES
PT78784B (en) ANTHRACYCLINE DERIVATIVES A MICROBIOLOGICAL PROCESS FOR THEIR PREPARATION AND THEIR USE AS CYTOSTATICS
CA2023089A1 (en) Method for the treatment of cardiac and of vascular hypertrophy and hyperplasia
DE19781038T1 (en) Keratinocyte growth factor 2 products
PL315052A1 (en) Condensed dihydropyridines, method of obtaining them, their application in producing pharmaceutic preparations and pharmaceutic preparations containing such compounds
NZ501709A (en) Pharmaceutical compositions comprising a compound having affinity for FKB12, a neurotrophic factor and a pharmaceuticl carrier
FR2760017B1 (en) NOVEL ERYTROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
DE69801811D1 (en) ALKYKENDIAMIN DI- OR TRI-ACETIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN COSMETIC COMPOSITIONS

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)