NZ501161A - Chimeric human trkA-IgG polypeptides which bind to human nerve growth factor. - Google Patents

Chimeric human trkA-IgG polypeptides which bind to human nerve growth factor.

Info

Publication number
NZ501161A
NZ501161A NZ501161A NZ50116195A NZ501161A NZ 501161 A NZ501161 A NZ 501161A NZ 501161 A NZ501161 A NZ 501161A NZ 50116195 A NZ50116195 A NZ 50116195A NZ 501161 A NZ501161 A NZ 501161A
Authority
NZ
New Zealand
Prior art keywords
human
bind
growth factor
nerve growth
trka
Prior art date
Application number
NZ501161A
Inventor
Leonard Presta
David L Shelton
Roman Urfer
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/286,846 external-priority patent/US5877016A/en
Priority claimed from US08/359,705 external-priority patent/US5844092A/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of NZ501161A publication Critical patent/NZ501161A/en

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The specification describes the use of a polypeptide comprising the second immunoglobulin-like domain of a human trkA sequence joined an immunoglobulin amino acid sequence to treat hyperalgesia.
NZ501161A 1994-03-18 1995-03-17 Chimeric human trkA-IgG polypeptides which bind to human nerve growth factor. NZ501161A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21513994A 1994-03-18 1994-03-18
US08/286,846 US5877016A (en) 1994-03-18 1994-08-05 Human trk receptors and neurotrophic factor inhibitors
US08/359,705 US5844092A (en) 1994-03-18 1994-12-20 Human TRK receptors and neurotrophic factor inhibitors
NZ33089795 1995-03-17

Publications (1)

Publication Number Publication Date
NZ501161A true NZ501161A (en) 2001-03-30

Family

ID=27484370

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ501161A NZ501161A (en) 1994-03-18 1995-03-17 Chimeric human trkA-IgG polypeptides which bind to human nerve growth factor.

Country Status (1)

Country Link
NZ (1) NZ501161A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10618974B2 (en) 2018-02-28 2020-04-14 Eli Lilly And Company Anti-TrkA antibody

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10618974B2 (en) 2018-02-28 2020-04-14 Eli Lilly And Company Anti-TrkA antibody

Similar Documents

Publication Publication Date Title
MX9603928A (en) HUMAN trk RECEPTORS AND NEUROTROPHIC FACTOR INHIBITORS.
PL336306A1 (en) Proteinous fusions of tgf-beta ii type receptor with a constant immunoglobulin area
AU4622297A (en) Monoclonal antibodies against the extracellular domain of human vegf-receptor protein (kdr)
WO1996037621A3 (en) Multimeric proteins
NZ330897A (en) Human trk receptors and neurotropic factor inhibitors
EP1200124A4 (en) Immunoglobulin fusion proteins
HK1017261A1 (en) Hybrid with interferon-alpha and an immunoglobulinfc linked through a non-immunogenic peptide.
ATE204300T1 (en) TARGET CELL-BINDING CHIMERIC PEPTIDES
EP0724456A4 (en) Antibodies to cd40
ZA915307B (en) Purification directed cloning of peptides
ATE223229T1 (en) COMPOSITIONS OF CONJUGATES OF THE STABLE, ACTIVE, HUMAN OB PROTEIN WITH THE FC CHAIN OF IMMUNOGLOBULINS AND RELATED METHODS
CA2312667A1 (en) Novel cytokine
WO1998055508A3 (en) HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS
AU4188789A (en) Urethane-protected amino acid-n-carboxyanhydrides
ZA932015B (en) Protein purification
AU1955388A (en) Method for potentiating and inhibiting insulin-like growth factor activity
NZ512083A (en) Methods of increasing lean tissue mass using OB protein compositions
HK1070669A1 (en) Growth hormone fusion protein
AU3125289A (en) Monoclonal antibodies directed against human tumor necrosis factor - receptor
CA2111645A1 (en) Fibrinogen fragment e peptides and antibodies thereto
DE59209129D1 (en) Use of antibody-containing preparations for immunosuppression
EP0619738A4 (en) Inhibitory immunoglobulin polypeptides to human pdgf beta receptor.
HK1030613A1 (en) Chimeric polypeptide comprising the fragment b of shiga toxin and peptides of therapeutic interest
EP0871661A4 (en) Novel protein domain which binds tyrosine phosphorylated proteins
NZ501161A (en) Chimeric human trkA-IgG polypeptides which bind to human nerve growth factor.

Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
EXPY Patent expired