NZ334649A - Iron regulated promoter derived from an aerobactin gene promoter - Google Patents

Iron regulated promoter derived from an aerobactin gene promoter

Info

Publication number
NZ334649A
NZ334649A NZ334649A NZ33464997A NZ334649A NZ 334649 A NZ334649 A NZ 334649A NZ 334649 A NZ334649 A NZ 334649A NZ 33464997 A NZ33464997 A NZ 33464997A NZ 334649 A NZ334649 A NZ 334649A
Authority
NZ
New Zealand
Prior art keywords
promoter
vector
dna sequence
derived
polypeptide
Prior art date
Application number
NZ334649A
Inventor
Himanshu N Brahmbhatt
David Emery
Adam Burn
Original Assignee
Australian Wool Res & Promotio
Commw Scient Ind Res Org
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPO2164A external-priority patent/AUPO216496A0/en
Priority claimed from AUPO2454A external-priority patent/AUPO245496A0/en
Priority claimed from AUPO7801A external-priority patent/AUPO780197A0/en
Application filed by Australian Wool Res & Promotio, Commw Scient Ind Res Org filed Critical Australian Wool Res & Promotio
Publication of NZ334649A publication Critical patent/NZ334649A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C07K14/4354—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The promoter comprises the DNA sequence (shown in the figure) or alternatively may comprise a fragment of this sequence including residues 284 to 409. In a vector, the promoter may be expressively linked to a further DNA sequence encoding a polypeptide such as B-cell or T-cell epitopes, CTL epitopes or the 37kD extracellular/secretory protein of Trichostrongylus colubriformis. Recombinant host cells containing this vector may be used in compositions for inducing an immune response in an animal. The hybrid iron-regulated promoter can be induced to hyper express the polypeptide encoding genes, providing an optimal dose to the host immune system.
NZ334649A 1996-09-06 1997-08-08 Iron regulated promoter derived from an aerobactin gene promoter NZ334649A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AUPO2164A AUPO216496A0 (en) 1996-09-06 1996-09-06 Inducible promoters
AUPO2454A AUPO245496A0 (en) 1996-09-19 1996-09-19 Site-specific chromosomal integration system
AUPO7801A AUPO780197A0 (en) 1997-07-09 1997-07-09 Site-specific chromosomal integration system incorporating inducible promoter
PCT/AU1997/000503 WO1998010064A1 (en) 1996-09-06 1997-08-08 Iron regulated promoter and uses thereof

Publications (1)

Publication Number Publication Date
NZ334649A true NZ334649A (en) 2000-08-25

Family

ID=27157946

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ334649A NZ334649A (en) 1996-09-06 1997-08-08 Iron regulated promoter derived from an aerobactin gene promoter

Country Status (7)

Country Link
EP (1) EP0964924A4 (en)
AR (1) AR008171A1 (en)
BR (1) BR9711692A (en)
CA (1) CA2265883A1 (en)
NZ (1) NZ334649A (en)
UY (1) UY24698A1 (en)
WO (1) WO1998010064A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0563311B1 (en) * 1990-12-18 2000-03-15 The General Hospital Corporation Improved vaccines
EP0692031B1 (en) * 1993-02-22 2007-04-11 The General Hospital Corporation Heterologous antigens in live cell vaccine strains

Also Published As

Publication number Publication date
CA2265883A1 (en) 1998-03-12
EP0964924A4 (en) 2001-04-18
EP0964924A1 (en) 1999-12-22
UY24698A1 (en) 1998-02-12
AR008171A1 (en) 1999-12-09
BR9711692A (en) 2000-10-24
WO1998010064A1 (en) 1998-03-12

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