NZ333030A - Compositions comprising solutes selected from raffinose, trehalose, trimethyl amine oxide and betaine, and use for the preservation of living tissues - Google Patents
Compositions comprising solutes selected from raffinose, trehalose, trimethyl amine oxide and betaine, and use for the preservation of living tissuesInfo
- Publication number
- NZ333030A NZ333030A NZ333030A NZ33303096A NZ333030A NZ 333030 A NZ333030 A NZ 333030A NZ 333030 A NZ333030 A NZ 333030A NZ 33303096 A NZ33303096 A NZ 33303096A NZ 333030 A NZ333030 A NZ 333030A
- Authority
- NZ
- New Zealand
- Prior art keywords
- preservation
- solutions
- biological material
- raffinose
- trehalose
- Prior art date
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Solutions and method for preserving biological material that enable organs, tissues and cells to be stored for extended periods of time with minimal loss of biological activity. The solutions may be either (i) substantially isotonic with the biological material to be preserved and are substantially free of univalent oxyanions and of iodide and/or (ii) comprise a first neutral solute having a molecular weight of at least about 335 and a solubility in water of at least about 0.3 M, and a second neutral solute having a molecular weight of less than about 200 and having both hydrophilic and hydrophobic moieties. The solutions preferably contain CaSO4, together with combinations of anions and cations from the protein-stabilizing ends of the Hofmeister series, such as K2SO4. The biological material may be pre-treated with sodium butyrate prior to the preservation solution.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/NZ1996/000057 WO1997047192A1 (en) | 1996-06-14 | 1996-06-14 | Compositions and methods for the preservation of living tissues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ333030A true NZ333030A (en) | 2000-05-26 |
Family
ID=19916330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ333030A NZ333030A (en) | 1996-06-14 | 1996-06-14 | Compositions comprising solutes selected from raffinose, trehalose, trimethyl amine oxide and betaine, and use for the preservation of living tissues |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JP2000512625A (en) |
| DE (1) | DE69625254T2 (en) |
| NZ (1) | NZ333030A (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY142987A (en) * | 2005-06-08 | 2011-02-14 | Hayashibara Biochem Lab | Solution for tissue adhesion prevention and method for tissue adhesion prevention |
| WO2007129618A1 (en) * | 2006-05-08 | 2007-11-15 | National University Corporation Kagawa University | Inhibitor of neutrophil activation/migration factor and use thereof |
| JP5753874B2 (en) * | 2010-11-09 | 2015-07-22 | 株式会社大塚製薬工場 | Cell viability decline inhibitor |
| WO2013161675A1 (en) * | 2012-04-27 | 2013-10-31 | 協和メデックス株式会社 | Method for stabilizing serum or plasma ascorbic acid |
| CN113795247B (en) * | 2018-12-14 | 2024-04-05 | 陈益祥 | Stable cardioplegia solution for cardiac surgery |
| CN112501024A (en) * | 2020-12-03 | 2021-03-16 | 英科新创（苏州）生物科技有限公司 | Universal quality control product preservation solution for in-vitro diagnosis kit |
-
1996
- 1996-06-14 JP JP09541244A patent/JP2000512625A/en not_active Abandoned
- 1996-06-14 NZ NZ333030A patent/NZ333030A/en unknown
- 1996-06-14 DE DE69625254T patent/DE69625254T2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69625254D1 (en) | 2003-01-16 |
| JP2000512625A (en) | 2000-09-26 |
| DE69625254T2 (en) | 2003-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RENW | Renewal (renewal fees accepted) |