NZ331264A - use of 1-aralkyl- 2-aryl substituted naphthyl derivatives in treating postmenopausal syndrome associated disorders, endometriosis or uterine fibroid disease
- Google Patents
use of 1-aralkyl- 2-aryl substituted naphthyl derivatives in treating postmenopausal syndrome associated disorders, endometriosis or uterine fibroid disease
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/309,525external-prioritypatent/US7501441B1/en
Application filed by Lilly Co ElifiledCriticalLilly Co Eli
Publication of NZ331264ApublicationCriticalpatent/NZ331264A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
The naphthyl derivatives of formula I or a pharmaceutically acceptable salt thereof are used in the manufacture of a medicament for treating the symptoms of postmenopausal syndrome in women or for inhibiting uterine fibroid disease, aortal smooth muscle cell proliferation, restenosis or endometriosis in women. In formula I: R1 and R2 are independently H, OH, -O-alkyl, -OCO-phenyl, -OCO-alkyl, or -OSO2-alkyl; n is 2 or 3; R3 is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholinyl, dimethylamino, diethylamino or 1-hexamethyleneimino.
NZ331264A1994-09-201995-09-18use of 1-aralkyl- 2-aryl substituted naphthyl derivatives in treating postmenopausal syndrome associated disorders, endometriosis or uterine fibroid disease
NZ331264A
(en)
use of 1-aralkyl- 2-aryl substituted naphthyl derivatives in treating postmenopausal syndrome associated disorders, endometriosis or uterine fibroid disease
Use of 3,4-diphenyl chroman derivatives in the manufacture of a medicament for lowering serum cholesterol levels and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease
use of 1-aralkyl- 2-aryl substituted naphthyl derivatives in treating postmenopausal syndrome associated disorders, endometriosis or uterine fibroid disease
Tetrahydroisoquinolinylcarbamates of 1,2,3,3A,8,8A-Hexahydro-1,3A,8-Trimethylpyrrolo[2,3-B]Indole or Their Isomers or Their Pharmaceutically Acceptable Acid-Additive Salts, Pharmaceutical Composition Containing Them and Method for Treatment