NZ239930A - Peptides related to a hirudin fragment but comprising synthetic amino acids, pseudopeptide bonds or non cysteine cyclisation - Google Patents

Peptides related to a hirudin fragment but comprising synthetic amino acids, pseudopeptide bonds or non cysteine cyclisation

Info

Publication number
NZ239930A
NZ239930A NZ239930A NZ23993091A NZ239930A NZ 239930 A NZ239930 A NZ 239930A NZ 239930 A NZ239930 A NZ 239930A NZ 23993091 A NZ23993091 A NZ 23993091A NZ 239930 A NZ239930 A NZ 239930A
Authority
NZ
New Zealand
Prior art keywords
cyclisation
amino acids
synthetic amino
peptides related
pseudopeptide bonds
Prior art date
Application number
NZ239930A
Inventor
Jean-Luc Fauchere
Christophe Thurieau
Isabelle Picard
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of NZ239930A publication Critical patent/NZ239930A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NZ239930A 1990-09-26 1991-09-25 Peptides related to a hirudin fragment but comprising synthetic amino acids, pseudopeptide bonds or non cysteine cyclisation NZ239930A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9011842A FR2667071A1 (en) 1990-09-26 1990-09-26 NOVEL THERAPEUTICALLY ACTIVE PEPTIDE AND PSEUDOPEPTIDE DERIVATIVES IN BLOOD COAGULATION CASCADE, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME.

Publications (1)

Publication Number Publication Date
NZ239930A true NZ239930A (en) 1993-01-27

Family

ID=9400651

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ239930A NZ239930A (en) 1990-09-26 1991-09-25 Peptides related to a hirudin fragment but comprising synthetic amino acids, pseudopeptide bonds or non cysteine cyclisation

Country Status (9)

Country Link
EP (1) EP0482966A3 (en)
JP (1) JPH04261197A (en)
AU (1) AU639827B2 (en)
CA (1) CA2052198A1 (en)
FR (1) FR2667071A1 (en)
IE (1) IE913361A1 (en)
NZ (1) NZ239930A (en)
PT (1) PT99054A (en)
ZA (1) ZA917700B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA907742B (en) * 1989-10-03 1991-07-31 Merrell Dow Pharma Anticoagulant peptides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340646C (en) * 1987-05-21 1999-07-13 John L. Krstenansky Cyclic anticoagulant peptides
HUT55799A (en) * 1988-09-29 1991-06-28 Biogen Inc Process for producing hirudine-like peptides
AU630132B2 (en) * 1988-12-07 1992-10-22 Merrell Dow Pharmaceuticals Inc. Anticoagulant peptides
AU640502B2 (en) * 1990-07-24 1993-08-26 Merrell Dow Pharmaceuticals Inc. Analogs of hirudin having antiplatelet activity

Also Published As

Publication number Publication date
EP0482966A2 (en) 1992-04-29
JPH04261197A (en) 1992-09-17
AU639827B2 (en) 1993-08-05
FR2667071A1 (en) 1992-03-27
EP0482966A3 (en) 1992-06-24
CA2052198A1 (en) 1992-03-27
PT99054A (en) 1992-08-31
AU8471091A (en) 1992-04-02
IE913361A1 (en) 1992-04-08
ZA917700B (en) 1992-06-24

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