NZ237271A - 4-(substituted amino)pyrid-3-yl sulphonyl urea derivatives; preparatory processes and pharmaceutical compositions - Google Patents

4-(substituted amino)pyrid-3-yl sulphonyl urea derivatives; preparatory processes and pharmaceutical compositions

Info

Publication number
NZ237271A
NZ237271A NZ237271A NZ23727191A NZ237271A NZ 237271 A NZ237271 A NZ 237271A NZ 237271 A NZ237271 A NZ 237271A NZ 23727191 A NZ23727191 A NZ 23727191A NZ 237271 A NZ237271 A NZ 237271A
Authority
NZ
New Zealand
Prior art keywords
pyrid
pharmaceutical compositions
substituted amino
urea derivatives
preparatory processes
Prior art date
Application number
NZ237271A
Inventor
Bernard Masereel
Bernard Pirotte
Marc Schynts
Jacques Delarge
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of NZ237271A publication Critical patent/NZ237271A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Derivatives of formula (I) <IMAGE> in which: - R denotes a cycloalkyl, bicycloalkyl or polycycloalkyl radical, - X denotes an oxygen or sulphur atom, - R1 denotes an alkyl, cycloalkyl, bicycloalkyl or polycycloalkyl radical. Medications.
NZ237271A 1990-03-02 1991-03-01 4-(substituted amino)pyrid-3-yl sulphonyl urea derivatives; preparatory processes and pharmaceutical compositions NZ237271A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9002659A FR2659080B1 (en) 1990-03-02 1990-03-02 NOVEL PYRIDYLSULFONYLUREA AND PYRIDYLSULFONYLTHIOURAE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Publications (1)

Publication Number Publication Date
NZ237271A true NZ237271A (en) 1993-04-28

Family

ID=9394324

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ237271A NZ237271A (en) 1990-03-02 1991-03-01 4-(substituted amino)pyrid-3-yl sulphonyl urea derivatives; preparatory processes and pharmaceutical compositions

Country Status (14)

Country Link
EP (1) EP0445039B1 (en)
JP (1) JPH07119216B2 (en)
AT (1) ATE106873T1 (en)
AU (1) AU632399B2 (en)
CA (1) CA2037189A1 (en)
DE (1) DE69102310T2 (en)
DK (1) DK0445039T3 (en)
ES (1) ES2057795T3 (en)
FR (1) FR2659080B1 (en)
IE (1) IE66021B1 (en)
NZ (1) NZ237271A (en)
OA (1) OA09485A (en)
PT (1) PT96926B (en)
ZA (1) ZA911524B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2685917A1 (en) * 1992-01-06 1993-07-09 Adir NOVEL PYRIDYLSULFONYLUREE DERIVATIVE OF PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
EP1276893A4 (en) 2000-04-14 2005-05-04 Univ Vanderbilt Purified and isolated potassium-chloride cotransporter nucleic acids and polypeptides and therapeutic and screening methods using same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1477664A (en) * 1974-04-17 1977-06-22 Christiaens Sa A Pyridine derivatives
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides

Also Published As

Publication number Publication date
CA2037189A1 (en) 1991-09-03
PT96926A (en) 1991-10-31
DK0445039T3 (en) 1994-10-31
FR2659080B1 (en) 1994-07-08
ATE106873T1 (en) 1994-06-15
JPH04211659A (en) 1992-08-03
AU7198191A (en) 1991-09-05
ZA911524B (en) 1991-12-24
IE910684A1 (en) 1991-09-11
ES2057795T3 (en) 1994-10-16
DE69102310D1 (en) 1994-07-14
DE69102310T2 (en) 1994-11-03
EP0445039A1 (en) 1991-09-04
IE66021B1 (en) 1995-11-29
EP0445039B1 (en) 1994-06-08
PT96926B (en) 1998-07-31
AU632399B2 (en) 1992-12-24
FR2659080A1 (en) 1991-09-06
JPH07119216B2 (en) 1995-12-20
OA09485A (en) 1992-11-15

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