NZ223184A - Certain 3-aryloxy-2-hydroxycyclopentylamines - Google Patents

Certain 3-aryloxy-2-hydroxycyclopentylamines

Info

Publication number
NZ223184A
NZ223184A NZ223184A NZ22318484A NZ223184A NZ 223184 A NZ223184 A NZ 223184A NZ 223184 A NZ223184 A NZ 223184A NZ 22318484 A NZ22318484 A NZ 22318484A NZ 223184 A NZ223184 A NZ 223184A
Authority
NZ
New Zealand
Prior art keywords
hydroxycyclopentylamines
aryloxy
certain
Prior art date
Application number
NZ223184A
Other languages
English (en)
Inventor
J R Mccarthy
M E Letourneau
D L Trepanier
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NZ223184A publication Critical patent/NZ223184A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/75—Reactions with formaldehyde
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/683—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
NZ223184A 1983-05-25 1984-05-21 Certain 3-aryloxy-2-hydroxycyclopentylamines NZ223184A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49777583A 1983-05-25 1983-05-25
NZ208230A NZ208230A (en) 1983-05-25 1984-05-21 Aryloxycycloalkanolaminoalkylenearyl (heteroaryl) ketones and pharmaceutical compositions

Publications (1)

Publication Number Publication Date
NZ223184A true NZ223184A (en) 1989-07-27

Family

ID=23978256

Family Applications (3)

Application Number Title Priority Date Filing Date
NZ223184A NZ223184A (en) 1983-05-25 1984-05-21 Certain 3-aryloxy-2-hydroxycyclopentylamines
NZ223185A NZ223185A (en) 1983-05-25 1984-05-21 Alpha-methylenearyl (heteroaryl) ketones
NZ208230A NZ208230A (en) 1983-05-25 1984-05-21 Aryloxycycloalkanolaminoalkylenearyl (heteroaryl) ketones and pharmaceutical compositions

Family Applications After (2)

Application Number Title Priority Date Filing Date
NZ223185A NZ223185A (en) 1983-05-25 1984-05-21 Alpha-methylenearyl (heteroaryl) ketones
NZ208230A NZ208230A (en) 1983-05-25 1984-05-21 Aryloxycycloalkanolaminoalkylenearyl (heteroaryl) ketones and pharmaceutical compositions

Country Status (19)

Country Link
EP (1) EP0127143B1 (OSRAM)
JP (1) JPS59231047A (OSRAM)
KR (1) KR890000021B1 (OSRAM)
AR (1) AR241900A1 (OSRAM)
AT (1) ATE51148T1 (OSRAM)
AU (3) AU566534B2 (OSRAM)
CA (1) CA1263656A (OSRAM)
DE (1) DE3481683D1 (OSRAM)
DK (1) DK256484A (OSRAM)
ES (2) ES8507530A1 (OSRAM)
GR (1) GR82032B (OSRAM)
HU (1) HU200440B (OSRAM)
IE (1) IE57535B1 (OSRAM)
IL (3) IL71891A (OSRAM)
NO (1) NO169588C (OSRAM)
NZ (3) NZ223184A (OSRAM)
PH (3) PH24747A (OSRAM)
PT (1) PT78638A (OSRAM)
ZA (1) ZA843836B (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH24747A (en) * 1983-05-25 1990-10-01 Merrell Dow Pharma Novel aryloxycycloalkanolaminoalkylene aryl ketons and method of use thereof
US5214169A (en) * 1988-04-25 1993-05-25 Merrell Dow Pharmaceuticals Inc. N-(2,3-epoxycyclopentyl) carbamate derivatives
CA1338868C (en) * 1988-04-25 1997-01-21 Theophilus F. Leapheart Process for the production of cis-hydroxy trans-phenoxycyclopentylamines
DE3840802A1 (de) * 1988-11-29 1990-05-31 Schering Ag 2-hydroxymethylthiophen-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JP2004010601A (ja) * 2002-06-11 2004-01-15 Nippon Steel Chem Co Ltd インドール誘導体の製造方法及びそのための有用な中間体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB249261A (en) * 1925-01-22 1926-03-25 Gen Electric Co Ltd Improvements in or relating to overspeed and overwinding gears for winding engines
DE1913199C3 (de) * 1969-03-15 1975-11-27 Beiersdorf Ag, 2000 Hamburg Mannichbasen aus alpha-Tetralon bzw. dessen Derivaten und Arylalkylaminen und deren Salze
DE3151201A1 (de) * 1981-12-23 1983-07-28 Beiersdorf Ag, 2000 Hamburg Substituierte phenoxyalkanolamine und phenoxyalkanol-cycloalkylamine, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische zubereitungen und zwischenprodukte
PH24747A (en) * 1983-05-25 1990-10-01 Merrell Dow Pharma Novel aryloxycycloalkanolaminoalkylene aryl ketons and method of use thereof

Also Published As

Publication number Publication date
AU7761787A (en) 1987-12-03
PT78638A (en) 1984-06-01
AR241900A1 (es) 1993-01-29
AU7761687A (en) 1987-12-03
IL71891A (en) 1991-03-10
NO169588C (no) 1992-07-15
ES532777A0 (es) 1985-09-01
IE841297L (en) 1984-11-25
AU608768B2 (en) 1991-04-18
NZ223185A (en) 1989-07-27
IL84452A (en) 1991-03-10
DE3481683D1 (de) 1990-04-26
ES8601849A1 (es) 1985-11-01
ATE51148T1 (de) 1990-04-15
NZ208230A (en) 1989-07-27
HUT36091A (en) 1985-08-28
EP0127143B1 (en) 1990-03-21
AU593679B2 (en) 1990-02-15
EP0127143A2 (en) 1984-12-05
HU200440B (en) 1990-06-28
IE57535B1 (en) 1992-10-07
KR890000021B1 (ko) 1989-03-06
DK256484D0 (da) 1984-05-24
PH23191A (en) 1989-05-29
GR82032B (OSRAM) 1984-12-12
CA1263656C (en) 1989-12-05
CA1263656A (en) 1989-12-05
IL84452A0 (en) 1988-04-29
AU566534B2 (en) 1987-10-22
IL84454A (en) 1991-03-10
IL71891A0 (en) 1984-09-30
IL84454A0 (en) 1988-04-29
AU2851684A (en) 1984-11-29
NO842078L (no) 1984-11-26
KR840009094A (ko) 1984-12-24
EP0127143A3 (en) 1985-05-29
ES536397A0 (es) 1985-11-01
DK256484A (da) 1984-11-26
PH23216A (en) 1989-06-06
JPH0530824B2 (OSRAM) 1993-05-11
ES8507530A1 (es) 1985-09-01
JPS59231047A (ja) 1984-12-25
PH24747A (en) 1990-10-01
ZA843836B (en) 1984-12-24
NO169588B (no) 1992-04-06

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