NZ221328A - A synergistic combination of t-pa and a prostaglandin, being pge, or a compound of formula i - Google Patents

A synergistic combination of t-pa and a prostaglandin, being pge, or a compound of formula i

Info

Publication number
NZ221328A
NZ221328A NZ221328A NZ22132887A NZ221328A NZ 221328 A NZ221328 A NZ 221328A NZ 221328 A NZ221328 A NZ 221328A NZ 22132887 A NZ22132887 A NZ 22132887A NZ 221328 A NZ221328 A NZ 221328A
Authority
NZ
New Zealand
Prior art keywords
pge
prostaglandin
compound
formula
synergistic combination
Prior art date
Application number
NZ221328A
Other languages
English (en)
Inventor
Brendan Joseph Richard Whittle
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10602253&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ221328(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of NZ221328A publication Critical patent/NZ221328A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ221328A 1986-08-05 1987-08-04 A synergistic combination of t-pa and a prostaglandin, being pge, or a compound of formula i NZ221328A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868619098A GB8619098D0 (en) 1986-08-05 1986-08-05 Combination

Publications (1)

Publication Number Publication Date
NZ221328A true NZ221328A (en) 1990-09-26

Family

ID=10602253

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ221328A NZ221328A (en) 1986-08-05 1987-08-04 A synergistic combination of t-pa and a prostaglandin, being pge, or a compound of formula i

Country Status (10)

Country Link
US (1) US4839169A (enExample)
EP (1) EP0257859B1 (enExample)
JP (1) JPS63115823A (enExample)
AU (1) AU589283B2 (enExample)
CA (1) CA1297010C (enExample)
DE (1) DE3773805D1 (enExample)
DK (1) DK163639C (enExample)
GB (1) GB8619098D0 (enExample)
NZ (1) NZ221328A (enExample)
ZA (1) ZA875755B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3544663A1 (de) * 1985-12-13 1987-06-19 Schering Ag Thrombosebehandlung mit fibrinolytika und prostacyclinen
EP0299376A3 (en) * 1987-07-13 1990-01-24 William Elson Shell Prostanoid compositions and methods for reducing blood vessel dysfunction
US5270198A (en) * 1988-05-20 1993-12-14 Genentech, Inc. DNA molecules encoding variants of tissue plasminogen activators, vectors, and host cells
US5342616A (en) * 1988-06-20 1994-08-30 The Wellcome Foundation Limited Method of administering tissue plasminogen activator
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
US5262170A (en) * 1988-09-02 1993-11-16 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
US5591446A (en) * 1989-04-04 1997-01-07 Beiersdorf, A.G. Methods and agents for the prophylaxis of atopy
WO1992011866A1 (en) * 1991-01-14 1992-07-23 Duke University LAMININ SEQUENCE AS tPA ACTIVATOR
JP3559559B2 (ja) * 1992-06-03 2004-09-02 ジェネンテク，インコーポレイテッド 向上した治療特性を有する組織プラスミノーゲン活性化因子グリコシル化変異体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4158667A (en) * 1976-02-04 1979-06-19 The Upjohn Company 6-Keto PGF analogs
US4539333A (en) * 1976-05-11 1985-09-03 Burroughs Wellcome Co. Prostacyclin, methods of using and method of making
FR2469411A1 (fr) * 1979-11-15 1981-05-22 Science Union & Cie Nouveaux derives de la piperidylbenzimidazolinone, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
EP0112122B1 (en) * 1982-12-14 1991-08-28 South African Inventions Development Corporation Plasminogen activator
US4661469A (en) * 1984-08-08 1987-04-28 Survival Technology, Inc. t-PA composition capable of being absorbed into the blood stream and method of administration
US4632919A (en) * 1984-09-27 1986-12-30 University Of Medicine & Dentistry Of N.J. Process for prolonging recalcification, prothrombin and thrombin times of plasma
EP0201153A3 (en) * 1985-02-09 1987-10-07 Beecham Group Plc Modified enzyme and process for its preparation
NL8601354A (nl) * 1985-05-28 1986-12-16 Wellcome Found Nieuwe samenstelling.
US4929444A (en) * 1985-05-28 1990-05-29 Burroughs Wellcome Co. Low pH pharmaceutical formulation containing t-PA
DE3544663A1 (de) * 1985-12-13 1987-06-19 Schering Ag Thrombosebehandlung mit fibrinolytika und prostacyclinen

Also Published As

Publication number Publication date
DE3773805D1 (de) 1991-11-21
JPS63115823A (ja) 1988-05-20
EP0257859A2 (en) 1988-03-02
ZA875755B (en) 1989-03-29
EP0257859B1 (en) 1991-10-16
DK163639B (da) 1992-03-23
DK405887D0 (da) 1987-08-04
CA1297010C (en) 1992-03-10
JPH0460586B2 (enExample) 1992-09-28
GB8619098D0 (en) 1986-09-17
AU589283B2 (en) 1989-10-05
US4839169A (en) 1989-06-13
EP0257859A3 (en) 1989-07-26
DK163639C (da) 1992-08-17
AU7657287A (en) 1988-02-11
DK405887A (da) 1988-02-06

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