NZ217366A - 6-phenoxymethyl-4-hydroxytetrahydropyran-2-one derivatives and pharmaceutical compositions; intermediates in the synthesis of such compounds - Google Patents

6-phenoxymethyl-4-hydroxytetrahydropyran-2-one derivatives and pharmaceutical compositions; intermediates in the synthesis of such compounds

Info

Publication number
NZ217366A
NZ217366A NZ217366A NZ21736686A NZ217366A NZ 217366 A NZ217366 A NZ 217366A NZ 217366 A NZ217366 A NZ 217366A NZ 21736686 A NZ21736686 A NZ 21736686A NZ 217366 A NZ217366 A NZ 217366A
Authority
NZ
New Zealand
Prior art keywords
hydroxytetrahydropyran
phenoxymethyl
intermediates
synthesis
derivatives
Prior art date
Application number
NZ217366A
Inventor
G Wess
E Granzer
G Beck
H-H Lau
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19853530798 external-priority patent/DE3530798A1/en
Priority claimed from DE19853543336 external-priority patent/DE3543336A1/en
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NZ217366A publication Critical patent/NZ217366A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NZ217366A 1985-08-29 1986-08-27 6-phenoxymethyl-4-hydroxytetrahydropyran-2-one derivatives and pharmaceutical compositions; intermediates in the synthesis of such compounds NZ217366A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853530798 DE3530798A1 (en) 1985-08-29 1985-08-29 6-Phenoxymethyl-4-hydroxytetrahydropyran-2-ones, processes for their preparation, their use as medicaments, pharmaceutical preparations and intermediates
DE19853543336 DE3543336A1 (en) 1985-12-07 1985-12-07 6-Phenoxymethyl-4-hydroxytetrahydropyran-2-ones, processes for their preparation, their use as medicaments, and pharmaceutical preparations and intermediates

Publications (1)

Publication Number Publication Date
NZ217366A true NZ217366A (en) 1989-08-29

Family

ID=25835464

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ217366A NZ217366A (en) 1985-08-29 1986-08-27 6-phenoxymethyl-4-hydroxytetrahydropyran-2-one derivatives and pharmaceutical compositions; intermediates in the synthesis of such compounds

Country Status (14)

Country Link
EP (1) EP0216127B1 (en)
KR (1) KR870002115A (en)
AU (1) AU6202986A (en)
DE (1) DE3674521D1 (en)
DK (1) DK409786A (en)
ES (1) ES2001594A6 (en)
FI (1) FI863470A (en)
GR (1) GR862208B (en)
HU (1) HUT44770A (en)
IL (1) IL79854A0 (en)
NO (1) NO863460L (en)
NZ (1) NZ217366A (en)
PH (1) PH23860A (en)
PT (1) PT83270B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3722809A1 (en) * 1987-07-10 1989-01-19 Hoechst Ag 3-DESMETHYL-4-FLUOR-MEVALONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS, THEIR USE AND INTERMEDIATE PRODUCTS
IL90249A (en) * 1988-05-13 1994-01-25 Hoechst Ag Hydroxytethrahydropyran-2-ones, the corresponding dihydroxycarboxylic acid derivatives and salts, process of preparation and pharmaceutical compositions containing them
US5166171A (en) * 1988-05-13 1992-11-24 Hoechst Aktiengesellschaft 6-phenoxymethyl-4-hydroxytetrahydropyran-2-ones and 6-thiphenoxymethyl-4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, and in treating hypercholesterolemia
NZ230121A (en) * 1988-08-29 1993-08-26 Squibb & Sons Inc Pyridine and quinoline terminal groups for hmg-coenzyme a reductase inhibitors and pharmaceutical compositions for lowering blood serum cholesterol levels
US5506219A (en) * 1988-08-29 1996-04-09 E. R. Squibb & Sons, Inc. Pyridine anchors for HMG-CoA reductase inhibitors
DE3929913A1 (en) * 1989-09-08 1991-04-04 Hoechst Ag 4-HYDROXYTETRAHYDROPYRAN-2-ONE AND THE CORRESPONDING DIHYDROXYCARBONSAEUREDERIVATES, SALTS AND ESTERS, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT, PHARMACEUTICAL PREPARATES AND PREPARED PRODUCTS
FR2653119B1 (en) * 1989-10-18 1994-08-05 Lipha NOVEL ARYLOXY ALCOYL BENZENES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.
CA2110251A1 (en) * 1992-11-30 1994-05-31 Koichi Fujimoto Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory diseases and psychosis
WO2001007031A1 (en) * 1999-07-26 2001-02-01 Shionogi & Co., Ltd. Benzene derivatives and immunopotentiating compositions or drug-sensitivity restoring agents containing the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5559180A (en) 1978-10-30 1980-05-02 Sankyo Co Ltd 4-hydroxy-2-pyrone ring compound, its preparation, and remedy for hyperlipemia comprising it as active constituent

Also Published As

Publication number Publication date
FI863470A (en) 1987-03-01
DE3674521D1 (en) 1990-10-31
EP0216127A2 (en) 1987-04-01
ES2001594A6 (en) 1988-06-01
PT83270A (en) 1986-09-01
HUT44770A (en) 1988-04-28
PH23860A (en) 1989-11-23
EP0216127B1 (en) 1990-09-26
DK409786A (en) 1987-03-01
AU6202986A (en) 1987-03-05
DK409786D0 (en) 1986-08-28
IL79854A0 (en) 1986-11-30
EP0216127A3 (en) 1987-06-16
NO863460D0 (en) 1986-08-28
KR870002115A (en) 1987-03-30
NO863460L (en) 1987-03-02
FI863470A0 (en) 1986-08-27
GR862208B (en) 1986-12-23
PT83270B (en) 1988-10-03

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