NZ212868A - Phenylnonatetraenoic acid derivatives and pharmaceutical compositions and intermediates therefor - Google Patents

Phenylnonatetraenoic acid derivatives and pharmaceutical compositions and intermediates therefor

Info

Publication number
NZ212868A
NZ212868A NZ212868A NZ21286885A NZ212868A NZ 212868 A NZ212868 A NZ 212868A NZ 212868 A NZ212868 A NZ 212868A NZ 21286885 A NZ21286885 A NZ 21286885A NZ 212868 A NZ212868 A NZ 212868A
Authority
NZ
New Zealand
Prior art keywords
phenylnonatetraenoic
pharmaceutical compositions
acid derivatives
intermediates therefor
intermediates
Prior art date
Application number
NZ212868A
Inventor
E R Aig
J W Coffey
A J Lovey
M Rosenberger
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NZ212868A publication Critical patent/NZ212868A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/42Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/48Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5456Arylalkanephosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ212868A 1984-07-27 1985-07-25 Phenylnonatetraenoic acid derivatives and pharmaceutical compositions and intermediates therefor NZ212868A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63510084A 1984-07-27 1984-07-27

Publications (1)

Publication Number Publication Date
NZ212868A true NZ212868A (en) 1989-05-29

Family

ID=24546455

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ212868A NZ212868A (en) 1984-07-27 1985-07-25 Phenylnonatetraenoic acid derivatives and pharmaceutical compositions and intermediates therefor

Country Status (23)

Country Link
EP (1) EP0169571B1 (en)
JP (1) JPH06716B2 (en)
KR (1) KR930000112B1 (en)
AR (1) AR242023A1 (en)
AT (1) ATE32882T1 (en)
AU (2) AU589130B2 (en)
CA (1) CA1277332C (en)
CS (1) CS256392B2 (en)
DE (1) DE3561808D1 (en)
DK (1) DK173287B1 (en)
ES (2) ES8703825A1 (en)
FI (1) FI84345C (en)
GR (1) GR851841B (en)
HU (1) HU195480B (en)
IE (1) IE58735B1 (en)
IL (1) IL75913A (en)
MC (1) MC1692A1 (en)
NO (1) NO161064C (en)
NZ (1) NZ212868A (en)
PH (1) PH21556A (en)
PT (1) PT80876B (en)
ZA (1) ZA854828B (en)
ZW (1) ZW12185A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ232865A (en) * 1989-03-21 1992-07-28 Hoffmann La Roche A mixed-micelle solution comprising a micelle former and an immunomodulator
DE4036779A1 (en) * 1990-11-17 1992-05-21 Basf Ag USE OF ARYLPOLYCAN CARBONIC ACIDS AND THEIR DERIVATIVES AS LIGHT PROTECTION AGENTS IN COSMETIC PREPARATIONS
US7655699B1 (en) 1992-04-22 2010-02-02 Eisai Inc. Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
US5369126A (en) * 1993-01-06 1994-11-29 Hoffmann-La Roche Inc. Nonatetraenoic acid derivative for use in treating acne
CA2129773C (en) * 1993-09-02 2007-05-01 Michael Klaus Aromatic carboxylic acid derivatives
US7115728B1 (en) 1995-01-30 2006-10-03 Ligand Pharmaceutical Incorporated Human peroxisome proliferator activated receptor γ
WO1999005161A1 (en) 1997-07-25 1999-02-04 Ligand Pharmaceuticals Incorporated HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA (PPARη) GENE REGULATORY SEQUENCES AND USES THEREFOR
US7547790B2 (en) * 2004-10-28 2009-06-16 Sankyo Company, Limited Optically active 4,4-di-substituted oxazolidine derivative and method for producing same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3334125A (en) * 1964-02-26 1967-08-01 Velsicol Chemical Corp Esters of 3-6-dichloro-2-methoxy-benzyl alcohol
CH585166A5 (en) * 1973-03-30 1977-02-28 Hoffmann La Roche
CH605562A5 (en) * 1974-09-26 1978-09-29 Hoffmann La Roche
DE2933985A1 (en) * 1979-08-22 1981-04-09 Bayer Ag, 5090 Leverkusen NEW 4-FLUOR-3-PHENOXY-BENZYL ETHERS AND METHOD FOR THEIR PRODUCTION AND NEW INTERMEDIATE PRODUCTS FOR THIS AND METHOD FOR THEIR PRODUCTION

Also Published As

Publication number Publication date
AU589130B2 (en) 1989-10-05
PT80876A (en) 1986-07-17
ES545565A0 (en) 1987-03-01
HU195480B (en) 1988-05-30
AU4260889A (en) 1990-01-25
EP0169571B1 (en) 1988-03-09
DK173287B1 (en) 2000-06-13
ZW12185A1 (en) 1986-02-26
DK340485D0 (en) 1985-07-25
JPS6143135A (en) 1986-03-01
ATE32882T1 (en) 1988-03-15
AR242023A1 (en) 1993-02-26
FI84345C (en) 1991-11-25
KR860001044A (en) 1986-02-22
DE3561808D1 (en) 1988-04-14
ZA854828B (en) 1986-03-26
CS550285A2 (en) 1987-08-13
AU619901B2 (en) 1992-02-06
IE851881L (en) 1986-01-27
MC1692A1 (en) 1986-07-18
EP0169571A1 (en) 1986-01-29
IE58735B1 (en) 1993-11-03
IL75913A (en) 1989-06-30
FI84345B (en) 1991-08-15
AU4557585A (en) 1986-01-30
DK340485A (en) 1986-01-28
PT80876B (en) 1987-11-30
PH21556A (en) 1987-12-11
NO852980L (en) 1986-01-28
KR930000112B1 (en) 1993-01-09
ES8705355A1 (en) 1987-05-01
FI852899L (en) 1986-01-28
HUT38306A (en) 1986-05-28
CS256392B2 (en) 1988-04-15
ES552061A0 (en) 1987-05-01
FI852899A0 (en) 1985-07-25
JPH06716B2 (en) 1994-01-05
IL75913A0 (en) 1985-12-31
GR851841B (en) 1985-12-02
ES8703825A1 (en) 1987-03-01
NO161064B (en) 1989-03-20
NO161064C (en) 1989-06-28
CA1277332C (en) 1990-12-04

Similar Documents

Publication Publication Date Title
NZ212415A (en) 2-benzimidazolyl 2-pyridylmethylsulphide derivatives and pharmaceutical compositions
IL74882A0 (en) Naphthyridine-,quinoline-and benzoxazine-carboxylic acids and derivatives thereof,their manufacture and pharmaceutical compositions containing them
IL76133A (en) Mercaptomethyl-octahydro-oxo-pyridazino(1,2-a)(1,2)diazepine-,diazocine-and(1,2,5)triazepinecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them and certain intermediates therefor
NZ212099A (en) Substituted arylhydroxamates and pharmaceutical compositions
GB2174904B (en) Vasculoprotecting pharmaceutical compositions
NZ211031A (en) 6-substituted-4-dialkylaminotetrahindole derivatives and pharmaceutical compositions
NZ211822A (en) Phenethanolamine derivatives and pharmaceutical compositions
KR870700608A (en) Amino-salicylic acid derivatives and pharmaceutical compositions
IL74865A0 (en) 9a-aza-9a-homoerythromycin derivatives and pharmaceutical compositions containing them
NZ212499A (en) Substituted benzamide derivatives and pharmaceutical compositions
GB2171600B (en) Pharmaceutical compositions
NZ211659A (en) Cephalosporin derivatives; intermediates and pharmaceutical compositions
IL76188A (en) 3-aralkylidene-hydroxy-flavanone derivatives and pharmaceutical compositions containing them
NZ213798A (en) Guanine derivatives and pharmaceutical compositions
EP0197752A3 (en) Pharmaceutical compositions
NZ210818A (en) 8-alpha-acylaminoergoline derivatives and pharmaceutical compositions
NZ215587A (en) 3-oxoandrost-4-ene-17beta-carboxylic acid ester derivatives and pharmaceutical compositions
NZ225466A (en) 1-aminoalkyl-1h-indole derivatives and pharmaceutical compositions containing certain derivatives thereof
NZ212868A (en) Phenylnonatetraenoic acid derivatives and pharmaceutical compositions and intermediates therefor
GB2167414B (en) Flavolignan derivatives and pharmaceutical compositions containing them
EP0191735A3 (en) Novel oxaluric acid derivatives and pharmaceutical compositions containing them
NZ214284A (en) Benzamide derivatives and pharmaceutical compositions
IL74190A (en) 6-substituted methylenepenicillanic acids and derivatives thereof and pharmaceutical compositions containing them
AU578104B2 (en) Pharmaceutical composition of peroxydiphosphoric acid derivatives
NZ210817A (en) N-hydroxy-alkoxynaphthalinalkanamine derivatives and pharmaceutical compositions