NO993662L - polymers - Google Patents

polymers

Info

Publication number
NO993662L
NO993662L NO993662A NO993662A NO993662L NO 993662 L NO993662 L NO 993662L NO 993662 A NO993662 A NO 993662A NO 993662 A NO993662 A NO 993662A NO 993662 L NO993662 L NO 993662L
Authority
NO
Norway
Prior art keywords
compounds
polymer backbone
polymers
therapeutic
branched
Prior art date
Application number
NO993662A
Other languages
Norwegian (no)
Other versions
NO993662D0 (en
Inventor
Louise Golding
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9701813.9A external-priority patent/GB9701813D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of NO993662D0 publication Critical patent/NO993662D0/en
Publication of NO993662L publication Critical patent/NO993662L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/124—Macromolecular compounds dendrimers, dendrons, hyperbranched compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0442—Polymeric X-ray contrast-enhancing agent comprising a halogenated group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyethers (AREA)

Abstract

Det beskrives forbindelser som omfatter et rettkjedet, forgrenet eller dendrimert polymerskjelett til hvilket det er koblet minst en reporterdel, hvor polymerskjelettet omfatter en pluralitet av aminholdige syrer. Slike forbindelser kan være tilkoblet til ett eller flere målsøkende midler og er egnet som terapeutiske og diagnostiske midler, særlig ved medisinske avbildningsteknikker.Compounds are disclosed which comprise a straight-chain, branched or dendrimeric polymer backbone to which at least one reporter moiety is attached, the polymer backbone comprising a plurality of amine-containing acids. Such compounds may be coupled to one or more targeting agents and are useful as therapeutic and diagnostic agents, especially by medical imaging techniques.

NO993662A 1997-01-29 1999-07-28 polymers NO993662L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9701813.9A GB9701813D0 (en) 1997-01-29 1997-01-29 Polymers
US5707497P 1997-08-27 1997-08-27
PCT/GB1998/000270 WO1998032469A2 (en) 1997-01-29 1998-01-29 Polymers

Publications (2)

Publication Number Publication Date
NO993662D0 NO993662D0 (en) 1999-07-28
NO993662L true NO993662L (en) 1999-09-28

Family

ID=26310882

Family Applications (1)

Application Number Title Priority Date Filing Date
NO993662A NO993662L (en) 1997-01-29 1999-07-28 polymers

Country Status (8)

Country Link
EP (1) EP1011736A2 (en)
JP (1) JP2001509796A (en)
KR (1) KR20000070544A (en)
CN (1) CN1246059A (en)
AU (1) AU5871798A (en)
CA (1) CA2278200A1 (en)
NO (1) NO993662L (en)
WO (1) WO1998032469A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6078399A (en) * 1998-09-29 2000-04-17 Arne Holm Ligand presenting assembly (lpa), method of preparation and uses thereof
WO2001002861A1 (en) * 1999-06-29 2001-01-11 Dako A/S Detection using dendrimers bearing labels and probes
ITFO990015A1 (en) * 1999-07-23 2001-01-23 Verdini Antonio "POLYPEPTIDE DENDRIMERS AS UNIMOLECULAR CARRIERS OF DRUGS AND BIOLOGICALLY ACTIVE SUBSTANCES".
KR100379720B1 (en) * 2000-10-14 2003-04-11 주식회사 마크로젠 Supporter containing drimer monolayer and manufacturing method of same
ATE494913T1 (en) * 2004-11-22 2011-01-15 Ge Healthcare As CONTRAST AGENTS FOR AN EXTRACELLULAR MATRIX
JP4870941B2 (en) * 2005-05-09 2012-02-08 公立大学法人大阪府立大学 High molecular compound
KR101334780B1 (en) * 2010-08-13 2013-12-02 한국생명공학연구원 Iodine-containing radial-shape macromolecular compounds, preparation method thereof and contrast medium compositions for CT comprising the same
WO2020142664A1 (en) * 2019-01-03 2020-07-09 Ionpath, Inc. Compositions and reagents for ion beam imaging
CN113307863B (en) * 2021-05-25 2022-12-16 华南农业大学 Preparation method and application of polyaspartic acid and salt antibody thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA839512B (en) * 1983-12-12 1984-08-29 Scripps Clinic Res Synthetic heat-stable enterotoxin polypeptide of escherichia coli and multimers thereof
DE3806795A1 (en) * 1988-02-29 1989-09-07 Schering Ag POLYMER-TIED COMPLEX IMAGERS, THEIR COMPLEXES AND CONJUGATES, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THEM
US5364613A (en) * 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
US5914095A (en) * 1989-04-07 1999-06-22 Salutar, Inc. Polychelants containg amide bonds
WO1993010824A1 (en) * 1991-12-04 1993-06-10 Guerbet S.A. Novel macromolecular polyamine iodine-containing compound, process for its preparation and its use as a contrast agent
JPH08501097A (en) * 1992-09-04 1996-02-06 ザ ゼネラル ホスピタル コーポレーション Biocompatible polymers including clinical diagnostic and therapeutic moieties
DE19521940A1 (en) * 1995-06-07 1996-12-12 Schering Ag Linear polyamines and polyamides containing iodine
US5756066A (en) * 1995-06-07 1998-05-26 Schering Aktiengesellschaft Iodine-containing peptides

Also Published As

Publication number Publication date
WO1998032469A3 (en) 1998-11-05
CA2278200A1 (en) 1998-07-30
WO1998032469A2 (en) 1998-07-30
NO993662D0 (en) 1999-07-28
KR20000070544A (en) 2000-11-25
EP1011736A2 (en) 2000-06-28
CN1246059A (en) 2000-03-01
JP2001509796A (en) 2001-07-24
AU5871798A (en) 1998-08-18

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application